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Carfilnat Injection

Original price was: ₹9,990.00.Current price is: ₹7,000.00.

 Prescription Required

 Cold chain

Salt : Bortezomib (2.5mg)

Manufacturer : Natco Pharma Ltd

Packing : 1 Injection in 1 vial

Prepaid Only, Non-Returnable

Description

Product Introduction

Carfilnat Injection contains Bortezomib (2.5mg) as its active ingredient and is used primarily in the treatment of multiple myeloma and mantle cell lymphoma. Bortezomib is a proteasome inhibitor, which means it blocks certain protein breakdown processes in cancer cells, ultimately leading to their death. This medicine is used under the strict supervision of a healthcare provider and is given as an intravenous (IV) or subcutaneous injection.

Carfilnat Injection is an advanced treatment option designed to slow the progression of cancer by interfering with cancerous cell growth and preventing tumor expansion. It is typically administered in cycles, often in combination with other chemotherapy drugs, to enhance its effectiveness.

This medication has shown promising results in patients with relapsed or refractory multiple myeloma (a type of blood cancer affecting plasma cells). Its targeted approach reduces the survival of malignant cells while sparing healthy tissues to some extent, making it a critical component in cancer therapy.

Uses of Carfilnat Injection (Bortezomib 2.5mg)

Carfilnat Injection is used in the treatment of:

  1. Multiple Myeloma – A type of blood cancer that affects plasma cells in the bone marrow. It is used as a first-line therapy or for patients whose disease has relapsed after prior treatments.
  2. Mantle Cell Lymphoma (MCL) – A rare and aggressive type of non-Hodgkin’s lymphoma. Bortezomib is used either alone or in combination with other chemotherapy drugs to manage the disease.
  3. Combination Therapy – Often used alongside Dexamethasone, Lenalidomide, or other anti-cancer medications to enhance effectiveness.
  4. Off-label Uses – In some cases, it may be used in research trials or under specialist recommendations for other conditions.

Benefits of Carfilnat Injection (Bortezomib 2.5mg)

Carfilnat Injection offers several benefits in the treatment of multiple myeloma and mantle cell lymphoma, making it a preferred choice among oncologists. Some of the key benefits include:

  1. Effective Cancer Treatment – Bortezomib targets cancerous cells, slowing disease progression and, in many cases, shrinking tumors.
  2. Improves Survival Rates – Clinical trials have shown that using Bortezomib can significantly improve progression-free survival and overall survival in multiple myeloma patients.
  3. Works When Other Treatments Fail – It is particularly useful in patients who have relapsed or not responded to other cancer treatments.
  4. Combination Therapy Compatibility – Can be combined with other anti-cancer drugs for improved efficacy.
  5. Less Damage to Healthy Cells – Compared to traditional chemotherapy, Bortezomib selectively targets proteasomes in cancer cells, reducing widespread harm to healthy cells.
  6. Can Be Given Subcutaneously – Unlike many chemotherapy drugs that require IV administration, Bortezomib can be given subcutaneously (under the skin), reducing the risk of infusion-related side effects.
  7. Reduces Bone Damage – Multiple myeloma weakens bones, but Bortezomib has been shown to help maintain bone integrity in patients by affecting osteoclast activity.

Side Effects of Carfilnat Injection (Bortezomib 2.5mg)

Like all cancer treatments, Carfilnat Injection can cause side effects. While not everyone experiences severe side effects, it is essential to be aware of potential adverse reactions.

Common Side Effects

  • Fatigue or weakness
  • Nausea and vomiting
  • Diarrhea or constipation
  • Loss of appetite
  • Fever or chills
  • Low blood platelet count (thrombocytopenia)
  • Peripheral neuropathy (tingling or numbness in hands and feet)

Serious Side Effects (Seek Immediate Medical Attention)

  • Severe nerve pain or muscle weakness
  • Breathing difficulties
  • Severe skin reactions (rash, redness, blistering)
  • Chest pain or irregular heartbeat
  • Low white blood cell count (increased risk of infections)
  • Liver dysfunction or increased liver enzymes

Managing Side Effects

Doctors may recommend medications, dietary changes, or supportive care to help manage these side effects. Patients should inform their healthcare provider if any symptoms persist or worsen.


Frequently Asked Questions (FAQ)

Q1: How does Carfilnat Injection work?

A: Carfilnat Injection contains Bortezomib, which inhibits proteasomes (enzymes that break down proteins in cancer cells). By blocking this process, it causes cancer cells to die, preventing tumor growth.

Q2: How is Carfilnat Injection administered?

A: It is given either as an intravenous (IV) infusion or subcutaneous (under the skin) injection under medical supervision. The dosage and frequency depend on the type of cancer being treated.

Q3: Can Carfilnat Injection be used alone, or does it require combination therapy?

A: It can be used alone but is often more effective when combined with other chemotherapy drugs like Dexamethasone, Lenalidomide, or Cyclophosphamide for better results.

Q4: What precautions should I take while receiving Carfilnat Injection?

A: Patients should:

  • Stay hydrated and maintain a healthy diet.
  • Avoid close contact with sick individuals (due to a weakened immune system).
  • Report any symptoms of nerve pain, bleeding, infections, or allergic reactions immediately.
  • Follow the doctor’s recommendations regarding dose scheduling.

Q5: Can I take Carfilnat Injection during pregnancy or breastfeeding?

A: No, this medication is not recommended during pregnancy as it can cause fetal harm. Women of childbearing age should use effective contraception. Breastfeeding is also not advised while receiving treatment.

Q6: How long does it take for Carfilnat Injection to show results?

A: The response time varies depending on the patient’s condition. Some patients may notice improvements within a few cycles, while others may require a longer duration. Regular monitoring via blood tests and scans helps assess progress.

Q7: Are there any dietary restrictions while taking this medicine?

A: While there are no strict dietary restrictions, it is recommended to:

  • Eat a balanced, protein-rich diet to support recovery.
  • Avoid alcohol and tobacco, as they may worsen side effects.
  • Stay well-hydrated and consume foods that are easy to digest.

Q8: What should I do if I miss a dose?

A: If you miss a dose, inform your doctor immediately. They will decide whether to adjust your treatment schedule. Do not double the dose to make up for a missed injection.

Q9: Is Carfilnat Injection safe for elderly patients?

A: Yes, but elderly patients may be more susceptible to side effects like neuropathy and low blood counts. Dose adjustments may be necessary based on their overall health condition.

Q10: Where can I buy Carfilnat Injection?

A: Carfilnat Injection (Bortezomib 2.5mg) is available at authorized pharmacies and online medical stores like onlinemedicos.co.in. Ensure you purchase from a trusted source to get genuine medication.


References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 209.
  2. Carfilzomib. Netherlands: Amgen Europe B.V.; 2015 [revised Sep. 2018]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  3. Carfilzomib. South San Francisco, California: Onyx Pharmaceuticals; 2012. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Disclaimer

Online Medicos primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on  Online Medicos Our mission is to support, not replace, the doctor-patient relationship

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Shipping & Delivery

Shipping Policy

We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

Delivery

The delivery times are subject to location, distance, and our logistics partners. We are not liable for any delays in delivery by the courier company/postal authorities but will help you track down a package through our partner courier services.

Your purchases may reach you from various locations in more than one package. But rest assured, you will be charged one delivery fee for the entire order. As soon as your package ships, we will email you your package tracking information.

We are bound in coverage by their reach even though we use some of India’s largest logistics companies for shipping. In case your address is in a location not served by them we would contact you to find an alternative solution to make your products reach you.