Samtica 250mg Tablet

1. Product Introduction

Samtica 250mg Tablet is a prescription medication that contains Abiraterone Acetate, a powerful anti-cancer drug used in the treatment of advanced prostate cancer. It belongs to a class of medicines called androgen biosynthesis inhibitors, which work by lowering the production of male hormones (androgens), particularly testosterone. Since prostate cancer cells use androgens to grow, reducing these hormone levels helps to stop or slow the cancer’s progression.

Abiraterone Acetate in Samtica 250mg inhibits a key enzyme known as CYP17, which is responsible for the synthesis of testosterone in the adrenal glands, testes, and prostate tumor tissue. By blocking this enzyme, the drug significantly reduces testosterone levels in the body — often to undetectable levels — thus preventing further cancer cell growth.

This medication is typically prescribed in combination with prednisone or prednisolone, a corticosteroid, to enhance treatment outcomes and reduce the risk of certain side effects. Samtica is administered orally and should be taken under the guidance and supervision of a healthcare provider.

2. Uses of Samtica 250mg Tablet

• Metastatic Castration-Resistant Prostate Cancer (mCRPC):
  Samtica is used in patients whose prostate cancer has spread to other parts of the body and is no longer responding to treatments that lower testosterone.

• Metastatic Castration-Sensitive Prostate Cancer (mCSPC):
  It is also prescribed for patients with newly diagnosed, high-risk prostate cancer that has spread but still responds to hormonal therapy.

• Post-Chemotherapy Prostate Cancer:
  Suitable for men who have undergone chemotherapy and need additional treatment to manage disease progression.

3. Benefits of Samtica 250mg Tablet

• Slows Cancer Progression:
  Samtica effectively suppresses testosterone levels, depriving cancer cells of the hormone they need to grow and divide.

• Improves Overall Survival:
  Clinical trials have shown that Abiraterone, the active salt in Samtica, significantly extends survival time in patients with advanced prostate cancer.

• Non-Invasive Treatment:
  Offers an oral, non-surgical alternative to traditional hormone deprivation therapies or surgical castration.

• Better Symptom Control:
  Helps in relieving symptoms such as bone pain, fatigue, and urinary difficulties, improving the patient’s quality of life.

• Convenient Dosage Form:
  The oral tablet form allows for easy administration at home, reducing hospital visits and improving treatment adherence.

• Can Be Combined with Other Therapies:
  Works well alongside corticosteroids, chemotherapy, or other hormonal therapies for maximum benefit.

4. Side Effects

As with all medications, Samtica 250mg Tablet may cause side effects, though not everyone experiences them. Most side effects are manageable and diminish as your body adjusts to the treatment.

Common Side Effects:

• High blood pressure (hypertension)

• Fluid retention or swelling in legs and ankles

• Low potassium levels (hypokalemia)

• Elevated liver enzymes

• Joint or muscle pain

• Tiredness and weakness

Serious Side Effects:

• Liver dysfunction (jaundice, dark urine, upper abdominal pain)

• Adrenal insufficiency

• Irregular heartbeat or chest pain

• Severe allergic reactions (rash, itching, shortness of breath)

Important Precautions:

• Samtica should be taken on an empty stomach — at least 1 hour before or 2 hours after eating.

• Regular monitoring of liver function, blood pressure, and potassium levels is essential.

• Must be taken in combination with prednisone or an equivalent steroid to prevent adrenal complications.

5. Frequently Asked Questions (FAQ)

Q1. What is Samtica 250mg used for?
A: Samtica is primarily used to treat advanced prostate cancer, especially when the cancer is resistant to other hormone treatments or has metastasized.

Q2. How does Samtica work?
A: It blocks the production of androgens (male hormones) by inhibiting the CYP17 enzyme, which helps slow or stop the growth of prostate cancer cells.

Q3. Can women or children take Samtica?
A: No. Samtica is only approved for use in adult men. It is not suitable for women or children, especially pregnant or breastfeeding women.

Q4. Should I take Samtica with food?
A: No. Samtica should always be taken on an empty stomach to avoid increased drug absorption, which can cause side effects.

Q5. Why do I need to take prednisone with Samtica?
A: Prednisone helps manage side effects like fluid retention and adrenal insufficiency caused by low cortisol levels during Abiraterone treatment.