

Mific Plus 100mg Injection
₹3,993.00 Original price was: ₹3,993.00.₹1,100.00Current price is: ₹1,100.00.
 Prescription Required
Salt : Minocycline
Manufacturer : Gufic Bioscience Ltd.
Packing : 1 vial
1. Product Introduction
Mific Plus 100mg Injection is a broad-spectrum antibiotic containing Minocycline, which belongs to the tetracycline class of antibiotics. It is administered intravenously and is commonly used in the hospital setting to treat a variety of moderate to severe bacterial infections. Minocycline works by inhibiting bacterial protein synthesis, thereby stopping the growth and multiplication of harmful bacteria.
This injection is especially useful when oral therapy is not feasible or in cases where rapid therapeutic action is required. Mific Plus 100mg Injection is known for its high potency, excellent tissue penetration, and effectiveness against a wide range of bacterial pathogens, including some antibiotic-resistant strains. The medicine is usually prescribed under medical supervision and is administered by a healthcare professional.
2. Uses of Mific Plus 100mg Injection
Mific Plus 100mg Injection is indicated for the treatment of various infections caused by susceptible strains of bacteria, such as:
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Respiratory tract infections (e.g., pneumonia, bronchitis)
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Skin and soft tissue infections
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Urinary tract infections (UTIs)
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Acne-related bacterial infections
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Sexually transmitted infections (like chlamydia)
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Infections caused by Rickettsia (e.g., Rocky Mountain spotted fever)
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Meningococcal carriers (as a preventive treatment)
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Anthrax (including inhalational exposure)
Minocycline may also be used in combination with other drugs to treat multidrug-resistant infections, particularly those caused by Methicillin-resistant Staphylococcus aureus (MRSA) and Acinetobacter baumannii.
3. Benefits of Mific Plus 100mg Injection
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Broad-Spectrum Activity:
Minocycline is effective against both gram-positive and gram-negative bacteria, including strains that are resistant to other antibiotics. -
Rapid Therapeutic Action:
As an injectable form, Mific Plus acts quickly, making it ideal for emergency or severe infections. -
Excellent Tissue Penetration:
Minocycline has superior ability to penetrate tissues, including cerebrospinal fluid, making it effective in central nervous system infections. -
Useful in Drug-Resistant Cases:
It is one of the few tetracyclines still effective against resistant strains like MRSA and multidrug-resistant Acinetobacter. -
Alternative for Penicillin-Allergic Patients:
Mific Plus is a reliable option for individuals allergic to penicillin or cephalosporins, offering effective treatment without cross-reactivity. -
Reduced Risk of Superinfections:
Compared to other broad-spectrum antibiotics, minocycline has a slightly lower risk of causing superinfections due to selective targeting.
4. Side Effects
As with any medication, Mific Plus 100mg Injection may cause side effects. While many patients tolerate it well, some may experience mild to moderate symptoms. Serious side effects are rare but can occur.
Common Side Effects:
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Dizziness or light-headedness
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Nausea and vomiting
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Diarrhea
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Headache
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Skin rash
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Injection site pain or swelling
Serious Side Effects (Seek immediate medical help):
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Hypersensitivity reactions (e.g., rash, swelling, itching, difficulty breathing)
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Hepatotoxicity (liver damage)
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Renal dysfunction
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Increased intracranial pressure (pseudotumor cerebri)
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Changes in skin pigmentation
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Autoimmune reactions (e.g., drug-induced lupus)
Regular monitoring of liver and kidney function may be recommended during prolonged therapy. Always inform your doctor if you experience unusual symptoms or if existing symptoms worsen.
5. Frequently Asked Questions (FAQs)
Q1: What is Mific Plus 100mg Injection used for?
A: Mific Plus is used to treat a variety of bacterial infections such as respiratory infections, skin infections, urinary tract infections, and more. It is especially useful in cases of drug-resistant infections or where oral therapy is not possible.
Q2: How is Mific Plus 100mg administered?
A: This medication is given as an intravenous injection by a qualified healthcare professional in a hospital or clinical setting.
Q3: Can Mific Plus 100mg Injection be used in children?
A: Minocycline is generally not recommended for children under the age of 8 years due to the risk of permanent tooth discoloration and effects on bone growth. It should be used in pediatric patients only when clearly needed and prescribed by a specialist.
Q4: Are there any dietary restrictions while using Mific Plus?
A: While the injectable form bypasses the digestive system, patients may still be advised to avoid supplements containing calcium, magnesium, aluminum, or iron, which may interfere with the drug’s effectiveness when switching to oral therapy.
Q5: Is it safe during pregnancy or breastfeeding?
A: No, Mific Plus is not recommended during pregnancy or breastfeeding. Minocycline may harm fetal development and can pass into breast milk. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
References
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Chambers HF, Deck DH. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidiones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 798.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 922, 1339-142.
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Minocycline [Product Information]. Triax Pharmaceuticals, LLC; 2010. [Accessed 20 Feb. 2024] (online) Available from:Â
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