Imatib 100mg Tablet

1. Product Introduction

Imatib 100mg Tablet is an oral anti-cancer medication containing Imatinib Mesylate (100mg), a targeted therapy drug used to treat specific types of cancers. It belongs to a class of medicines known as tyrosine kinase inhibitors (TKIs). Imatinib works by inhibiting the activity of abnormal proteins (tyrosine kinases) that promote the growth of cancer cells.

Imatib is a well-established treatment and was one of the first targeted therapies approved for cancer treatment. It is most notably used in the management of Chronic Myeloid Leukemia (CML) and Gastrointestinal Stromal Tumors (GIST). Imatib 100mg is prescribed by oncologists and hematologists, and long-term use under medical supervision can significantly control disease progression and improve patient survival.

2. Uses of Imatib 100mg Tablet

Imatib 100mg Tablet is used for treating various types of cancers and conditions where abnormal tyrosine kinase activity is present. The key indications include:

• Chronic Myeloid Leukemia (CML):
  Effective in treating all phases of CML – chronic, accelerated, and blast crisis phases.

• Acute Lymphoblastic Leukemia (ALL):
  Used in Philadelphia chromosome-positive (Ph+) ALL, a specific subtype.

• Gastrointestinal Stromal Tumors (GIST):
  Used for GISTs that are unresectable or have metastasized, especially those with KIT mutations.

• Myelodysplastic/Myeloproliferative Diseases (MDS/MPD):
  Especially those associated with PDGFR gene rearrangements.

• Systemic Mastocytosis:
  Used in aggressive forms that are associated with certain gene mutations.

• Hypereosinophilic Syndrome and Chronic Eosinophilic Leukemia (HES/CEL)

• Dermatofibrosarcoma Protuberans (DFSP):
  A rare skin cancer responsive to Imatinib treatment.

It is usually taken once or twice daily, depending on the condition being treated, and under close medical supervision.

3. Benefits of Imatib 100mg Tablet

• Targeted Cancer Therapy:
  Unlike traditional chemotherapy, Imatib targets specific cancer-causing proteins, reducing harm to normal cells.

• High Efficacy in CML:
  Helps patients achieve remission and live longer with chronic myeloid leukemia. Many patients have long-term disease control with Imatinib.

• Reduced Risk of Relapse:
  Continuous therapy lowers the chance of disease recurrence and progression.

• Well-Tolerated Over Time:
  It is generally well-tolerated with proper dose adjustments and regular monitoring, even with long-term use.

• Oral Administration:
  Offers the convenience of being taken orally at home, reducing the need for frequent hospital visits.

• Improves Quality of Life:
  Especially in CML and GIST patients, it significantly improves symptoms, blood counts, and overall well-being.

4. Side Effects of Imatib 100mg Tablet

While Imatib is a powerful medicine, it can cause side effects, some of which may require medical attention or dose adjustment.

Common Side Effects:

• Nausea and vomiting

• Muscle cramps or joint pain

• Fatigue or tiredness

• Abdominal pain

• Rash or skin irritation

• Diarrhea

• Headache

• Fluid retention (swelling in hands, feet, or around eyes)

Less Common or Serious Side Effects:

• Liver function abnormalities

• Low blood cell counts (anemia, leukopenia, thrombocytopenia)

• Heart problems (rare cases of congestive heart failure)

• Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis)

• Kidney dysfunction

• Gastrointestinal bleeding (especially in GIST patients)

Precautions and Monitoring:

• Regular blood tests are required to monitor blood counts, liver and kidney function.

• Dose adjustments may be needed based on tolerability.

• Not recommended during pregnancy or breastfeeding unless absolutely necessary.

• Caution in patients with liver, kidney, or heart disease.

5. Frequently Asked Questions (FAQ)

Q1. What is Imatib 100mg Tablet used for?
A1. Imatib is used to treat various cancers, especially Chronic Myeloid Leukemia (CML), Gastrointestinal Stromal Tumors (GIST), and some rare forms of leukemia and skin cancer.

Q2. How does Imatib work?
A2. Imatib works by blocking specific proteins (tyrosine kinases) that cause cancer cells to grow and multiply. This helps in stopping or slowing down the growth of cancer.

Q3. How should I take Imatib 100mg Tablet?
A3. It should be taken orally with a glass of water, preferably after food to avoid stomach upset. Your doctor will prescribe the correct dose based on your condition.

Q4. Can Imatib be taken long-term?
A4. Yes. In many patients, especially those with CML, Imatib is taken for years. Regular monitoring ensures safety and effectiveness over the long term.

Q5. What should I do if I miss a dose?
A5. If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed one. Do not double the dose.