

Abione 250mg Tablet
₹30,193.00 Original price was: ₹30,193.00.₹17,000.00Current price is: ₹17,000.00.
 Prescription Required
Salt : Abiraterone Acetate
Manufacturer : INTAS PHARMACEUTICALS LTD
Packing : 120 TABLET(s) IN A BOTTLE
1. Product Introduction
Abione 250mg Tablet is a prescription medication used in the treatment of advanced prostate cancer. It contains Abiraterone Acetate, a type of hormonal therapy that plays a crucial role in managing prostate cancer, particularly when the disease is no longer responding to standard hormone treatments.
Abiraterone Acetate belongs to a class of drugs known as androgen biosynthesis inhibitors. It works by reducing the production of androgens (male hormones like testosterone) in the body. These hormones can stimulate the growth of prostate cancer cells. By lowering androgen levels, Abione slows down or stops the progression of prostate cancer.
This medicine is typically prescribed in combination with a corticosteroid, such as prednisone or prednisolone, to minimize the side effects associated with hormonal changes and to enhance its effectiveness.
Abione is administered orally, offering a non-invasive treatment approach that is convenient for patients managing long-term therapy. Regular medical supervision and routine blood tests are important to monitor your response to this medication.
2. Uses of This Medicine
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Treatment of metastatic castration-resistant prostate cancer (mCRPC)
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Treatment of metastatic high-risk castration-sensitive prostate cancer (mCSPC)
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Used alongside corticosteroids to prevent treatment-related side effects
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Helps in lowering androgen levels in the body
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Delays disease progression and improves overall survival rates
3. Benefits of This Medicine
âś” Controls Cancer Progression
Abione effectively lowers the levels of testosterone and other androgens, which are responsible for the growth and spread of prostate cancer cells. This helps in slowing disease progression and managing symptoms.
âś” Improves Survival and Quality of Life
Studies have shown that Abiraterone-based treatments improve overall survival in patients with metastatic prostate cancer. Patients also experience a better quality of life by managing symptoms such as pain, fatigue, and urinary discomfort.
âś” Convenient Oral Therapy
Unlike intravenous chemotherapy or hormone injections, Abione is taken orally, making it a more comfortable and manageable option for long-term use, especially for elderly patients.
âś” Delays Need for Chemotherapy
In many cases, Abione can delay the need for chemotherapy, which is often associated with more severe side effects. This makes it a valuable option in early advanced stages of prostate cancer.
âś” Reduces Cancer-Related Symptoms
By controlling hormonal imbalances, Abione helps in relieving symptoms like bone pain, weight loss, urinary obstruction, and fatigue—common in advanced prostate cancer patients.
4. Side Effects
Like all medications, Abione 250mg Tablet may cause side effects. Most side effects are manageable and go away with time, but it is important to be aware of them and consult a doctor if they persist or worsen.
Common Side Effects:
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High blood pressure (Hypertension)
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Low potassium levels (Hypokalemia)
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Swelling in legs or feet (Fluid retention)
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Increased liver enzymes
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Joint pain
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Muscle discomfort
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Fatigue or weakness
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Hot flushes
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Indigestion
Serious Side Effects (Seek immediate medical help):
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Liver problems (yellowing of eyes or skin, dark urine)
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Irregular heartbeat
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Adrenal insufficiency (extreme tiredness, low blood pressure, dizziness)
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Severe allergic reactions (rash, itching, swelling)
Note:
Regular monitoring of blood pressure, liver function, and potassium levels is essential while taking Abione. Always follow your doctor’s guidance closely.
5. Frequently Asked Questions (FAQ)
Q1. What is Abione 250mg Tablet used for?
A: Abione is used for treating advanced prostate cancer in men, especially when the disease is resistant to other hormonal therapies or has spread to other parts of the body.
Q2. How does Abione work?
A: It works by inhibiting the enzyme CYP17, which plays a key role in the production of androgens. Reducing these hormones slows the growth of prostate cancer cells.
Q3. Can I take Abione with food?
A: No. Abione should be taken on an empty stomach, at least one hour before or two hours after meals, as food increases its absorption and may lead to side effects.
Q4. Why is Abione taken with prednisone?
A: Abione reduces corticosteroid levels in the body. Prednisone is taken alongside to balance these levels, reduce inflammation, and minimize side effects like high blood pressure or low potassium.
Q5. What happens if I miss a dose?
A: If you miss a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one. Do not double the dose to make up for the missed one. Always follow your doctor’s schedule.
Q6. Is Abione a form of chemotherapy?
A: No. Abione is a hormonal therapy, not chemotherapy. It works by interfering with hormone production rather than directly killing cancer cells.
Q7. Can women or children use Abione?
A: No. Abione is intended only for adult men. Women, especially those who are pregnant or breastfeeding, should avoid handling crushed or broken tablets.
Q8. How long should I take Abione?
A: The duration depends on your response to treatment and your doctor’s recommendation. Some patients take it for several months or even years under medical supervision.
Q9. Are there any lifestyle changes recommended while taking Abione?
A: Yes. Follow a low-sodium, balanced diet, stay hydrated, limit alcohol, avoid grapefruit juice, and monitor your blood pressure regularly.
References
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
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CiplaMed. Abiraterone Acetate [Prescribing Information]. [Accessed 25 Jul. 2024] (online) Available from:Â
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