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Abiratas 250mg Tablet

Original price was: ₹30,193.00.Current price is: ₹14,000.00.

  Prescription Required

Salt : Abiraterone Acetate

Manufacturer : Intas Pharmaceuticals Ltd

Packing : 120 tablets in 1 bottle

Description

1. Product Introduction

Abiratas 250mg Tablet is a prescription medication containing Abiraterone Acetate, a potent hormonal therapy used in the treatment of prostate cancer. It belongs to a class of drugs known as androgen biosynthesis inhibitors. This medicine works by blocking the production of androgens (male hormones such as testosterone), which fuel the growth of prostate cancer cells.

Abiratas is primarily prescribed for metastatic castration-resistant prostate cancer (mCRPC) and metastatic high-risk castration-sensitive prostate cancer (mCSPC). It is often administered along with corticosteroids like prednisone to help balance hormone levels and minimize side effects.

Prostate cancer is one of the most common cancers affecting men globally. When it spreads or stops responding to standard hormone therapies, advanced treatment like Abiratas becomes necessary. Taken orally under medical supervision, Abiratas offers an effective and non-invasive treatment option to slow the progression of the disease and improve the patient’s quality of life.


2. Uses of This Medicine

  • Treatment of metastatic castration-resistant prostate cancer (mCRPC)

  • Treatment of metastatic high-risk castration-sensitive prostate cancer (mCSPC)

  • Used in combination with corticosteroids to reduce side effects of hormonal changes

  • Helps in reducing tumor size and slowing cancer spread

  • Enhances survival and delays cancer-related complications


3. Benefits of This Medicine

âś” Effective Hormonal Suppression:
Abiratas blocks the activity of an enzyme called CYP17, which is responsible for androgen production in the adrenal glands, testes, and prostate tumor tissue. By doing so, it deprives prostate cancer cells of the hormones they need to grow.

âś” Proven Results in Advanced Prostate Cancer:
Clinical studies show that Abiraterone-based treatments like Abiratas significantly improve overall survival in men with advanced prostate cancer, especially when combined with corticosteroids.

âś” Improved Symptom Control:
Abiratas helps manage painful symptoms associated with prostate cancer such as bone pain, urinary problems, and fatigue. It can also reduce the need for opiates and other pain-relieving drugs.

âś” Oral Administration:
Unlike many cancer treatments that require hospital visits and injections, Abiratas is taken orally, offering convenience and ease of use for patients undergoing long-term therapy.

âś” Delays Disease Progression:
By controlling androgen levels effectively, Abiratas slows down the progression of the disease, delays the onset of complications, and improves patient well-being.


4. Side Effects

While Abiratas 250mg Tablet is well-tolerated by many patients, it may cause some side effects. These effects are often manageable and should be monitored closely during treatment.

Common Side Effects:

  • High blood pressure (Hypertension)

  • Low blood potassium levels (Hypokalemia)

  • Fluid retention (Swelling in legs or ankles)

  • Elevated liver enzymes

  • Joint pain

  • Hot flushes

  • Fatigue

  • Indigestion

Serious Side Effects (Require Immediate Medical Attention):

  • Liver toxicity (Signs include yellowing of eyes/skin, dark urine)

  • Irregular heartbeat

  • Muscle weakness or cramps due to low potassium

  • Adrenal insufficiency (Symptoms include dizziness, nausea, low blood pressure)

Note:
Regular monitoring of blood pressure, potassium levels, and liver function tests is essential while using this medication. Always report any unusual or persistent symptoms to your doctor immediately.


5. Frequently Asked Questions (FAQ)

Q1. What is Abiratas 250mg Tablet used for?
A: Abiratas is used to treat prostate cancer that has spread to other parts of the body and is no longer responding to traditional hormonal treatments. It is typically used in advanced or high-risk metastatic prostate cancer.

Q2. How does Abiratas work in prostate cancer treatment?
A: Abiratas works by blocking androgen (male hormone) production in the body. Since prostate cancer cells depend on these hormones to grow, reducing hormone levels slows cancer progression.

Q3. Can I take Abiratas with food?
A: No, Abiratas should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal, as food can increase the absorption of the drug and raise the risk of side effects.

Q4. Can I stop taking Abiratas if I feel better?
A: No, you should continue taking Abiratas exactly as prescribed. Stopping it without your doctor’s guidance can lead to a rapid return of cancer symptoms.

Q5. Are there any lifestyle precautions while on Abiratas?
A: Yes, it’s important to maintain a healthy diet, stay hydrated, avoid high-sodium foods, and monitor your blood pressure regularly. Also, avoid grapefruit or grapefruit juice as it may interfere with the drug’s effectiveness.


References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
  2. Abiraterone acetate. High Wycombe, Buckinghamshire: Janssen-Cilag Ltd.; 2017. [Accessed 26 Mar. 2019] (online) Available from:External Link
  3. Abiraterone Acetate. Patheon Inc.: Mississauga, Canada; 2011 [revised May 2016]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
  5. Abiraterone acetate [Prescribing Information]. Toronto, Canada: Patheon Inc.; 2011. [Accessed 20 Feb. 2024] (online) Available from: External Link
  6. CiplaMed. Abiraterone Acetate [Prescribing Information]. [Accessed 25 Jul. 2024] (online) Available from: External Link


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We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

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