Adbiron 250mg Tablet

1. Product Introduction

Adbiron 250mg Tablet is an anti-cancer medication that contains Abiraterone Acetate (250mg) as its active ingredient. It is primarily used in the treatment of prostate cancer that has spread to other parts of the body (metastatic prostate cancer). Prostate cancer cells require testosterone to grow, and Abiraterone works by blocking the production of testosterone, thereby slowing the progression of cancer.

This medicine is often prescribed in combination with prednisone or prednisolone to reduce certain side effects and improve the effectiveness of the treatment. Adbiron is taken orally and is usually recommended to be taken on an empty stomach as food can increase its absorption and potentially lead to side effects.

Abiraterone is a trusted and widely used hormonal therapy that has been proven to significantly improve survival rates and quality of life for patients with advanced prostate cancer. It is not recommended for use in women or children and should be taken strictly under the supervision of a qualified oncologist.

2. Uses of Adbiron 250mg Tablet

Adbiron 250mg Tablet is primarily used in the treatment of:

• Metastatic Castration-Resistant Prostate Cancer (mCRPC): Prostate cancer that continues to grow despite low testosterone levels (often seen in advanced stages).

• Metastatic High-Risk Castration-Sensitive Prostate Cancer (mCSPC): Cancer that has spread and still responds to hormonal therapy.

It is prescribed as part of a hormonal therapy regimen and may be combined with corticosteroids and other cancer medications depending on the patient’s condition.

3. Benefits of Adbiron 250mg Tablet

Adbiron offers several key benefits in the treatment of advanced prostate cancer:

• Blocks Testosterone Production at the Source: Unlike some other treatments, Abiraterone targets the enzyme CYP17, which is involved in testosterone production not only in the testes but also in the adrenal glands and cancer cells.

• Improves Survival Rates: Clinical studies have shown that patients taking Abiraterone live significantly longer compared to those receiving only standard hormone therapy.

• Reduces Cancer-Related Symptoms: By lowering testosterone levels, it helps shrink the tumor and provides relief from cancer symptoms such as bone pain and urinary discomfort.

• Oral Convenience: Being a tablet-based therapy, it eliminates the need for injections, making it easier for patients to take it at home.

• Delays the Need for Chemotherapy: Abiraterone can delay disease progression, potentially postponing the need for more aggressive treatments like chemotherapy.

• Well-Tolerated: With proper monitoring and supportive medication like prednisone, it is generally well-tolerated with manageable side effects.

4. Side Effects of Adbiron 250mg Tablet

Like all medications, Adbiron 250mg Tablet may cause side effects. It’s important to monitor for these and consult a doctor if they persist or worsen.

Common Side Effects:

• High blood pressure (Hypertension)

• Low potassium levels (Hypokalemia)

• Swelling in legs and feet (Fluid retention)

• Liver function abnormalities

• Fatigue or weakness

• Joint pain

• Hot flashes

Less Common or Serious Side Effects:

• Increased cholesterol or blood sugar levels

• Heart-related issues (irregular heartbeat)

• Adrenal gland suppression

• Allergic reactions (rash, itching, swelling)

• Shortness of breath

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  References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
  2. Abiraterone acetate. High Wycombe, Buckinghamshire: Janssen-Cilag Ltd.; 2017. [Accessed 26 Mar. 2019] (online) Available from:
  3. Abiraterone Acetate. Patheon Inc.: Mississauga, Canada; 2011 [revised May 2016]. [Accessed 26 Mar. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
  5. Abiraterone acetate [Prescribing Information]. Toronto, Canada: Patheon Inc.; 2011. [Accessed 20 Feb. 2024] (online) Available from: 

  6. CiplaMed. Abiraterone Acetate [Prescribing Information]. [Accessed 25 Jul. 2024] (online) Available from: 

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