Alkeprost 250mg Tablet

1. Product Introduction

Alkeprost 250mg Tablet is a prescription oral medication containing Abiraterone Acetate, a potent androgen biosynthesis inhibitor. It is primarily prescribed to treat prostate cancer in men, particularly metastatic castration-resistant prostate cancer (mCRPC) and metastatic high-risk castration-sensitive prostate cancer (mCSPC). This medicine is part of a newer class of hormonal therapies aimed at reducing the production of androgens (male hormones) which fuel the growth of prostate cancer cells.

Manufactured for high therapeutic value, Alkeprost is usually given alongside a corticosteroid (like prednisone) to minimize certain side effects and enhance efficacy. It is taken orally on an empty stomach, ideally at the same time each day. This medicine should always be used under the supervision of a qualified healthcare provider or oncologist.

2. Uses of This Medicine

Alkeprost 250mg Tablet is used in the treatment of:

• Metastatic Castration-Resistant Prostate Cancer (mCRPC):
  This type of prostate cancer continues to progress even after surgical or medical castration (removal of testosterone effects). Alkeprost helps to further suppress the production of androgens to slow cancer progression.

• Metastatic High-Risk Castration-Sensitive Prostate Cancer (mCSPC):
  In newly diagnosed patients whose cancer has already spread, Alkeprost is used in combination with androgen deprivation therapy (ADT) and corticosteroids.

• After Failure of Initial Hormonal Therapies:
  It is commonly prescribed when initial hormone treatments no longer control the cancer, offering patients another treatment option before or after chemotherapy.

3. Benefits of This Medicine

• Inhibits Cancer Progression:
  Alkeprost effectively slows down the progression of advanced prostate cancer by inhibiting the enzyme CYP17, crucial for androgen production.

• Prolongs Survival:
  Clinical studies have shown that Abiraterone-based treatments like Alkeprost significantly improve overall survival in prostate cancer patients.

• Oral Dosage Convenience:
  Alkeprost is administered orally, allowing patients to take it at home, thus improving treatment comfort and compliance.

• Non-Chemotherapy Option:
  It serves as a targeted hormonal therapy, offering an alternative for patients who may not be suitable candidates for chemotherapy.

• Improves Quality of Life:
  By managing disease progression and reducing symptoms like pain, fatigue, and urinary difficulties, Alkeprost improves patients’ daily functioning and quality of life.

4. Side Effects

Like all powerful cancer treatments, Alkeprost 250mg may cause side effects. Most are manageable and monitored by healthcare providers during treatment.

Common Side Effects:

• High blood pressure (hypertension)

• Low potassium levels (hypokalemia)

• Fluid retention or swelling (edema)

• Increased liver enzymes

• Joint pain or muscle aches

• Fatigue and weakness

Less Common but Serious Side Effects:

• Irregular heartbeat

• Liver dysfunction (hepatotoxicity)

• Adrenal insufficiency

• Bone thinning or fractures

• Urinary infections

Important Note:
Patients taking Alkeprost are often monitored regularly for blood pressure, liver function, and potassium levels. It is strongly advised not to discontinue or alter the dosage without medical consultation.

5. Frequently Asked Questions (FAQ)

Q1. What is Alkeprost 250mg Tablet used for?
A: Alkeprost is used to treat advanced or metastatic prostate cancer, particularly in patients who have failed traditional hormone therapies.

Q2. How does Alkeprost work in the body?
A: Alkeprost contains Abiraterone Acetate, which blocks CYP17, an enzyme involved in androgen (male hormone) production. By reducing androgens, it helps slow or stop the growth of prostate cancer cells.

Q3. Should I take Alkeprost with food?
A: No. Alkeprost should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal to avoid enhanced absorption and side effects.

Q4. Why is prednisone used with Alkeprost?
A: Prednisone helps reduce side effects caused by excess mineralocorticoid production due to Abiraterone, such as fluid retention, high blood pressure, and low potassium levels.

Q5. Can women or children use Alkeprost?
A: No. Alkeprost is only indicated for use in adult males. It is not recommended for women or pediatric patients.