Alkeprost 500mg Tablet

1. Product Introduction

Alkeprost 500mg Tablet is a prescription medication that contains Abiraterone Acetate, a powerful anti-cancer agent classified as an androgen biosynthesis inhibitor. It is widely used in the treatment of advanced or metastatic prostate cancer in adult men. By inhibiting the production of androgens (male hormones), which fuel the growth of prostate cancer cells, Alkeprost helps to slow down the progression of the disease.

This high-dose formulation (500mg) allows for greater convenience by reducing the number of tablets a patient needs to take daily. It is commonly prescribed alongside a corticosteroid like prednisone to reduce certain side effects and to enhance therapeutic effectiveness. Alkeprost should be taken on an empty stomach, either one hour before or two hours after eating.

2. Uses of This Medicine

Alkeprost 500mg Tablet is used for the treatment of:

• Metastatic Castration-Resistant Prostate Cancer (mCRPC):
  For patients whose prostate cancer continues to progress despite hormone therapy or surgical castration.

• Metastatic High-Risk Castration-Sensitive Prostate Cancer (mCSPC):
  Newly diagnosed patients with cancer that has spread outside the prostate and is still responsive to hormone therapy.

• Post-chemotherapy or Hormone Therapy Failure:
  In men who have not responded to other standard treatments, Alkeprost is an effective next step to control the disease.

It is a long-term treatment and must be taken consistently as directed by a qualified healthcare professional.

3. Benefits of This Medicine

• Effectively Reduces Tumor Progression:
  Alkeprost inhibits the enzyme CYP17, a key player in androgen production. Reducing androgen levels helps to slow or stop the growth of cancer cells in the prostate.

• Improves Survival Rate:
  Clinical studies have shown that Abiraterone-based treatment significantly improves the overall survival and progression-free survival of prostate cancer patients.

• Fewer Tablets, More Convenience:
  The 500mg strength allows for a reduced pill burden, making it easier for patients to adhere to treatment.

• Non-Chemotherapy Option:
  As a hormonal therapy, it offers a less aggressive treatment route for patients not eligible or willing to undergo chemotherapy.

• Symptom Relief and Better Quality of Life:
  Alkeprost helps alleviate cancer-related symptoms, such as bone pain, fatigue, and urinary obstruction, improving daily functioning and well-being.

4. Side Effects

Although Alkeprost 500mg Tablet is generally well-tolerated, like all cancer medications, it may cause side effects. These are usually monitored and managed by the treating oncologist.

Common Side Effects:

• High blood pressure (hypertension)

• Low potassium levels (hypokalemia)

• Fluid retention or swelling (edema)

• Liver function abnormalities (increased liver enzymes)

• Fatigue and general weakness

• Joint and muscle pain

Serious Side Effects (Less Common):

• Irregular heartbeat

• Liver toxicity

• Adrenal insufficiency

• Bone thinning (osteoporosis)

• Increased risk of infections

Patients on Alkeprost require regular monitoring of blood pressure, liver enzymes, potassium levels, and other vital signs to ensure safe and effective treatment.

5. Frequently Asked Questions (FAQ)

Q1. What is Alkeprost 500mg used for?
A: Alkeprost is used to treat advanced stages of prostate cancer, especially when the cancer continues to grow despite hormone therapy.

Q2. How does Abiraterone in Alkeprost work?
A: It works by blocking CYP17, an enzyme needed for androgen production. This reduces male hormone levels, slowing the growth of prostate cancer cells.

Q3. How should I take this medication?
A: Take Alkeprost once daily on an empty stomach (1 hour before or 2 hours after a meal), with water. It is typically taken with a corticosteroid like prednisone to prevent side effects.

Q4. Can women or children take Alkeprost?
A: No. Alkeprost is strictly for use in adult men. It should not be used by women, especially pregnant women, or children.

Q5. Why is prednisone given with Alkeprost?
A: Alkeprost can increase the production of certain steroids in the body. Prednisone helps balance this effect and prevents side effects like fluid retention and low potassium.

Reference:

For more information on Abiraterone Acetate, you can consult the following references:

1. Clinical Study on Abiraterone Acetate in Prostate Cancer:

   • FDA Drug Approval: Abiraterone Acetate is approved by the U.S. FDA for the treatment of prostate cancer. It has been extensively studied in clinical trials that show its effectiveness in slowing the progression of metastatic prostate cancer.

2. National Cancer Institute (NCI):

   • The NCI provides detailed information on Abiraterone and its uses in cancer treatment, including its application in castration-resistant prostate cancer.

   • National Cancer Institute – Abiraterone

3. Journal of Clinical Oncology:

   • Various research papers and clinical trials published in the Journal of Clinical Oncology provide data on the efficacy and safety of Abiraterone in prostate cancer patients.

   • Journal of Clinical Oncology – Abiraterone Studies

Disclaimer

Online Medicos primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on  Online Medicos Our mission is to support, not replace, the doctor-patient relationship.