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Bdpazo 400mg Tablet

Original price was: ₹3,510.00.Current price is: ₹2,600.00.

  Prescription Required

  Cold chain

Salt : Pazopanib

Manufacturer : Bdr Pharmaceuticals Internationals Pvt

Packing : 30 Tablets In A Bottle

Prepaid Only, Non-Returnab

Description

1. Product Introduction

Bdpazo 400mg Tablet is an oral anticancer medication that contains Pazopanib as its active ingredient. Pazopanib belongs to a class of drugs known as tyrosine kinase inhibitors (TKIs). It works by blocking certain proteins (receptors) that are involved in the growth of blood vessels that supply tumors. By doing so, it helps to prevent cancer cells from growing and spreading.

Bdpazo is mainly prescribed for patients with kidney cancer and soft tissue sarcoma. It is used when the cancer is advanced, metastatic (has spread to other parts of the body), or not responding to previous treatments. The tablet is typically taken once daily on an empty stomach and should only be used under the supervision of an oncologist or cancer specialist.

This medication plays a crucial role in modern cancer therapy by targeting specific molecular pathways, thereby offering a more precise and potentially less toxic alternative to traditional chemotherapy.


2. Uses of Bdpazo 400mg Tablet

Bdpazo 400mg Tablet is used in the treatment of:

  • Advanced Renal Cell Carcinoma (RCC): This is the most common type of kidney cancer in adults. Bdpazo helps in slowing down or stopping tumor growth in patients who are not candidates for surgery or have recurrent disease.

  • Advanced Soft Tissue Sarcoma (STS): Pazopanib is indicated in cases where other chemotherapeutic options have failed. It is effective in treating various subtypes of STS in adult patients.

  • Other Off-Label Uses (under specialist guidance): Occasionally, oncologists may prescribe Pazopanib for other cancers with similar molecular targets, based on clinical judgment and emerging research.


3. Benefits of Bdpazo 400mg Tablet

  • Targeted Cancer Therapy: Bdpazo targets the VEGFR, PDGFR, and other tyrosine kinases involved in angiogenesis (formation of new blood vessels), effectively starving the tumor of its blood supply.

  • Improves Progression-Free Survival: Clinical trials have shown that patients on Pazopanib experience a longer period before the disease progresses, compared to placebo.

  • Oral Administration: Being available as a tablet, it offers the convenience of home-based treatment without the need for hospital visits for infusions.

  • Effective in Resistant Cases: It is especially beneficial in patients whose cancers are not responding to first-line treatments.

  • Well-Studied: Pazopanib has undergone extensive clinical evaluation, making it a reliable and evidence-backed treatment for advanced cancers.


4. Side Effects

As with any cancer treatment, Bdpazo 400mg Tablet can cause side effects. However, not everyone experiences them, and they may vary in severity.

Common Side Effects:

  • Diarrhea

  • High blood pressure

  • Fatigue

  • Loss of appetite

  • Nausea or vomiting

  • Changes in hair color

  • Weight loss

  • Abnormal liver function tests

Serious Side Effects (seek immediate medical attention):

  • Liver toxicity (jaundice, dark urine, yellowing of eyes)

  • Heart issues (chest pain, irregular heartbeat)

  • Bleeding problems

  • Blood clots

  • Reversible Posterior Leukoencephalopathy Syndrome (a rare brain disorder)

  • Delayed wound healing

Monitoring:
Regular monitoring of liver function, blood pressure, heart function, and other parameters is essential during treatment with Pazopanib to ensure early detection of any adverse effects.


5. Frequently Asked Questions (FAQ)

Q1. How should Bdpazo 400mg Tablet be taken?
A: It should be taken orally once a day on an empty stomach, at least one hour before or two hours after a meal. It must be taken at the same time every day for consistent drug levels in the body.

Q2. Can I stop the medicine if I feel better?
A: No. Cancer medications must be taken as prescribed. Stopping the drug without medical advice can lead to cancer progression or relapse.

Q3. What should I do if I miss a dose?
A: If it is less than 12 hours since the missed dose, take it as soon as you remember. If more than 12 hours have passed, skip the missed dose and take the next one at the usual time. Do not double the dose.

Q4. Is Bdpazo safe during pregnancy?
A: No. Pazopanib can harm an unborn baby and is not recommended during pregnancy or breastfeeding. Effective contraception is advised for both men and women during treatment and for a period after stopping it.

Q5. Can Bdpazo be used in children?
A: Bdpazo is not approved for use in children or adolescents under 18 years of age, as safety and efficacy have not been established in this age group.


References

  1. Highlights Of Prescribing Information – Pazopanib. [Revised on 2021] [cited 2023 Mar 24]. Available from: https://www.novartis.com/us-en/sites/novartis_us/files/votrient.pdf
  2. Summary Of Product Characteristics – Pazopanib. [revised on 2021] [cited 2023 Mar 24]. Available from: https://www.ema.europa.eu/en/documents/product-information/votrient-epar-product-information_en.pdf
  3. Votrient 400 mg film coated tablets – Summary of Product Characteristics (SmPC) – (emc). www.medicines.org.uk. 2021 [cited 2023 Mar 24]. Available from: https://www.medicines.org.uk/emc/product/572/smpc
  4. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.Disclaimer

    Disclaimer

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We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

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