Bonmax PTH 750mcg Solution for Injection

1. Product Introduction

Bonmax PTH 750mcg Solution for Injection is a prescription medication used primarily for the treatment of osteoporosis. It contains Teriparatide, a synthetic form of the human parathyroid hormone (PTH 1-34), which plays a vital role in bone metabolism. Teriparatide works by stimulating new bone formation, thereby improving bone strength and reducing the risk of fractures.

Bonmax PTH is available as a pre-filled pen injector or vial for subcutaneous injection and is intended for once-daily administration. It is typically prescribed when other treatments for osteoporosis have failed or are not well tolerated. This medicine is particularly effective in patients with severe osteoporosis, postmenopausal women, men with primary or hypogonadal osteoporosis, and those with osteoporosis induced by long-term steroid use.

It is important that Bonmax PTH be used under the supervision of a healthcare provider, along with proper diet, calcium, and vitamin D supplementation as advised.

2. Uses of This Medicine

Bonmax PTH is used in the management and treatment of conditions involving bone loss or fragility:

✅ Osteoporosis in Postmenopausal Women:

• Reduces the risk of vertebral and non-vertebral fractures in women with severe osteoporosis or multiple risk factors.

✅ Osteoporosis in Men:

• Used in men with primary or hypogonadal osteoporosis to increase bone mass and reduce fracture risk.

✅ Glucocorticoid-Induced Osteoporosis:

• Helps patients on chronic corticosteroid therapy, which often leads to bone loss, by stimulating new bone growth.

✅ High Fracture Risk Patients:

• Ideal for patients who are at high risk for fractures or have experienced prior fractures related to bone weakness.

Bonmax PTH is not intended for use in growing children, patients with bone cancer, or those with unexplained elevated levels of alkaline phosphatase.

3. Benefits of This Medicine

Bonmax PTH 750mcg offers significant therapeutic advantages in managing osteoporosis, especially in high-risk individuals.

🌟 Stimulates New Bone Formation:

Unlike anti-resorptive agents that only slow bone breakdown, Teriparatide actively stimulates new bone growth, restoring bone structure.

🌟 Reduces Fracture Risk:

Regular use significantly reduces the risk of spinal and hip fractures, improving mobility and quality of life.

🌟 Improves Bone Mineral Density (BMD):

Leads to substantial increases in BMD at the spine and hip, which are critical sites for osteoporotic fractures.

🌟 Well-Tolerated and Easy to Use:

Delivered as a once-daily subcutaneous injection, making it simple for home administration with proper training.

🌟 Fast-Acting Therapy:

Starts showing improvements in bone formation markers within a few months of treatment.

🌟 Safe for Long-Term Steroid Users:

Beneficial for those on long-term corticosteroids who are at high risk of secondary osteoporosis.

4. Side Effects

While Bonmax PTH is generally well tolerated, some patients may experience side effects. Most side effects are mild to moderate in nature and tend to diminish over time.

Common Side Effects:

• Nausea

• Headache

• Dizziness

• Muscle cramps

• Joint pain

• Injection site reactions (pain, redness, or swelling)

Less Common but Serious Side Effects:

• Hypercalcemia (elevated calcium levels)

• Kidney stones

• Hypotension (low blood pressure)

• Allergic reactions (rash, itching, swelling)

Rarely, long-term animal studies have shown an increased risk of osteosarcoma (bone cancer) with Teriparatide use. However, this has not been conclusively seen in humans. As a precaution, treatment is typically limited to 24 months over a patient’s lifetime.

5. Frequently Asked Questions (FAQ)

Q1. What is Bonmax PTH 750mcg used for?

A: It is used to treat osteoporosis in postmenopausal women, men with osteoporosis, and individuals with steroid-induced bone loss to reduce the risk of fractures.

Q2. How does Teriparatide work?

A: Teriparatide mimics the action of natural parathyroid hormone, stimulating bone-forming cells (osteoblasts) and increasing bone mineral density by promoting new bone growth.

Q3. How should I take Bonmax PTH?

A: It is administered as a once-daily injection under the skin (subcutaneous), usually in the thigh or abdomen. Follow your healthcare provider’s instructions on proper technique.

Q4. Can I self-administer the injection at home?

A: Yes, with proper training from a healthcare provider or nurse, you can safely self-administer Bonmax PTH at home using the pre-filled injection pen or vial.

Q5. How long can I take Bonmax PTH?

A: Treatment is usually limited to 24 months (2 years) in a lifetime due to the theoretical risk of osteosarcoma with prolonged use.