

Borviz 2mg Injection
₹3,892.00 Original price was: ₹3,892.00.₹1,800.00Current price is: ₹1,800.00.
 Prescription Required
Salt : Bortezomib (2mg)
Manufacturer : Intas Pharmaceuticals Ltd
Packing : 1Â Injection in 1 vial
1. Product Introduction
Borviz 2mg Injection is a chemotherapy medication that contains Bortezomib (2mg) as its active ingredient. It belongs to a class of medicines known as proteasome inhibitors and is primarily used in the treatment of certain types of blood cancers such as multiple myeloma and mantle cell lymphoma. Borviz is administered intravenously (IV) or subcutaneously (under the skin) by a healthcare professional in a clinical setting.
Bortezomib works by interfering with the growth and survival of cancer cells. It blocks a protein complex called the proteasome, which plays a crucial role in regulating cell function and survival. By disrupting this system, Borviz promotes cancer cell death, thereby slowing the progression of the disease.
Borviz 2mg Injection is a potent drug and must be used under strict medical supervision. It is often used in combination with other anti-cancer drugs like dexamethasone or thalidomide to enhance its effectiveness.
2. Uses of This Medicine
Borviz 2mg Injection is indicated for the treatment of:
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Multiple Myeloma: A cancer of plasma cells in the bone marrow. Borviz is effective in newly diagnosed as well as relapsed or refractory multiple myeloma cases.
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Mantle Cell Lymphoma: A type of aggressive non-Hodgkin lymphoma that affects the lymphatic system.
Doctors may also consider its off-label use for other cancers under specific circumstances, but the primary approval remains for the two types of blood cancers mentioned above.
3. Benefits of This Medicine
The key benefits of Borviz 2mg Injection include:
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Effective Cancer Control: Bortezomib targets cancer cells specifically, disrupting their internal machinery and preventing their multiplication.
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Improved Survival Rates: Clinical trials have shown that patients treated with Borviz often experience longer progression-free survival and better overall outcomes, especially when used in combination therapy.
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Rapid Onset of Action: The medicine starts acting soon after administration, often leading to quick reduction in symptoms like bone pain, fatigue, or weakness caused by multiple myeloma.
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Enhanced Treatment Response: When used as part of a combination regimen, Borviz improves response rates, meaning more cancer cells are destroyed or reduced in activity.
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Manageable Side Effect Profile: Compared to many traditional chemotherapies, Borviz has a manageable side effect profile, particularly when patients are monitored and dosages are adjusted carefully.
4. Side Effects
Like all anti-cancer medications, Borviz 2mg Injection can cause side effects. However, not everyone experiences them, and many are manageable with proper medical care. Common and serious side effects include:
Common Side Effects:
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Fatigue and weakness
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Nausea and vomiting
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Diarrhea or constipation
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Loss of appetite
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Low platelet or white blood cell counts (increased risk of infection or bleeding)
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Peripheral neuropathy (tingling, numbness, or pain in the hands and feet)
Serious Side Effects:
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Severe infections (due to suppressed immune function)
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Hypotension (low blood pressure)
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Liver enzyme elevation
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Congestive heart failure in rare cases
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Severe gastrointestinal issues such as bleeding or obstruction
If any of these side effects are experienced, especially the severe ones, it is critical to contact a healthcare provider immediately.
5. Frequently Asked Questions (FAQs)
Q1. What is Borviz 2mg Injection used for?
A: Borviz 2mg Injection is used to treat multiple myeloma and mantle cell lymphoma. These are cancers that affect the bone marrow and lymphatic system, respectively.
Q2. How is Borviz administered?
A: Borviz is given either as an intravenous (IV) injection or subcutaneously (under the skin), usually in a hospital or clinic by a trained healthcare provider.
Q3. Can Borviz be used alone?
A: While Borviz can be used as a monotherapy, it is most effective when used in combination with other chemotherapy agents such as dexamethasone or thalidomide.
Q4. How long is the treatment duration with Borviz?
A: The treatment duration depends on the type and stage of cancer, how well the patient responds, and the overall treatment plan. Typically, it is given in cycles with rest periods in between.
Q5. What precautions should be taken during treatment?
A: Regular blood tests, hydration, and monitoring for signs of infection or nerve damage are essential. Patients should avoid alcohol, stay well-hydrated, and report any side effects to their doctor promptly.
References
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Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1742-43.
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Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 958.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 153-54.
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Bortezomib [Prescribing Information]. Cambridge, MA: Millennium Pharmaceuticals, Inc.; 2008. [Accessed 25 Jul. 2024] (online) Available from:Â
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