Celzar 1000mg Injection
Original price was: ₹5,168.00.₹2,800.00Current price is: ₹2,800.00.
 Prescription Required
Salt : Gemcitabine (1000mg)
Manufacturer : Celon Laboratories Ltd
Packing : vial of 1 injection
1. Product Introduction:
Celzar 1000mg Injection contains Gemcitabine, a chemotherapy medication used to treat various types of cancers. It belongs to the class of drugs known as antimetabolites, which work by interfering with the DNA replication process in cancer cells, thereby inhibiting their growth and multiplication.
Administered intravenously under the supervision of a healthcare professional, Celzar is usually given in cycles, allowing the body to recover between doses. It is widely used as a monotherapy or in combination with other chemotherapy agents, depending on the type and stage of cancer.
This injection is a cornerstone in modern oncology, particularly for patients with aggressive or advanced cancers, as it helps to shrink tumors, relieve symptoms, and extend survival time.
2. Uses of This Medicine:
Celzar 1000mg Injection is indicated for the treatment of various cancers, including but not limited to:
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Pancreatic Cancer
Used as a first-line treatment, especially for advanced or metastatic pancreatic cancer. -
Non-Small Cell Lung Cancer (NSCLC)
Either alone or in combination with other chemotherapeutic agents like cisplatin. -
Bladder Cancer
Often used in combination regimens to treat advanced or metastatic cases. -
Breast Cancer
Used when other treatments have failed or as part of a combination therapy. -
Ovarian Cancer
Administered in relapsed cases, usually alongside carboplatin. -
Biliary Tract Cancer
Sometimes used in treating cancers of the gallbladder or bile ducts.
Its usage may vary based on cancer stage, patient health, and treatment goals (curative vs. palliative).
3. Benefits of This Medicine:
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Effective Against Multiple Cancers:
Gemcitabine is approved and widely used to treat a broad range of solid tumors. -
Improves Survival Rates:
Clinical studies show increased survival in patients treated with Gemcitabine, especially in lung and pancreatic cancer. -
Combination Therapy Advantage:
Can be combined with other chemotherapy agents to enhance cancer-fighting effectiveness. -
Symptom Relief:
Helps reduce tumor size, relieving symptoms like pain, obstruction, and breathlessness in certain cancers. -
Flexible Dosing Schedules:
Allows adjustment in dosing cycles based on patient condition and response. -
Proven Safety Profile:
Although side effects exist, it is generally well-tolerated with manageable adverse effects under medical supervision.
4. Side Effects:
Like all chemotherapy medications, Celzar 1000mg Injection can cause side effects. These may vary depending on the dose, treatment duration, and the individual’s health condition.
Common Side Effects:
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Nausea and vomiting
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Fatigue or weakness
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Low blood cell counts (anemia, neutropenia, thrombocytopenia)
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Fever or chills
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Hair loss (temporary)
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Mild skin rash
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Loss of appetite
Serious Side Effects:
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Severe bone marrow suppression
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Liver function abnormalities (elevated liver enzymes)
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Kidney toxicity
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Pulmonary toxicity (shortness of breath, cough, or lung inflammation)
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Allergic reactions (swelling, difficulty breathing)
Regular monitoring through blood tests is essential during treatment to detect and manage these effects promptly. Always consult your oncologist if any unusual or severe symptoms appear.
5. Frequently Asked Questions (FAQ):
Q1. What is Celzar 1000mg Injection used for?
A: It is used to treat various types of cancers including pancreatic, lung, bladder, breast, ovarian, and biliary tract cancers.
Q2. How is Celzar Injection administered?
A: Celzar is administered intravenously by a healthcare professional in a hospital or clinic setting. The infusion is usually given over 30 minutes to an hour.
Q3. Can this medication be taken at home?
A: No, it must be given under medical supervision in a clinical setting due to the risk of side effects and the need for close monitoring.
Q4. Is Celzar a curative treatment?
A: It may not cure all types of cancers but can significantly slow disease progression, shrink tumors, relieve symptoms, and improve quality of life.
Q5. How long is the treatment cycle with Celzar?
A: It depends on the type and stage of cancer. Typically, it is given on specific days in a 21- or 28-day cycle. Your doctor will determine the exact schedule.
References
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Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1700-701.
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Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 947-48.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 617-18.
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Drug.com. Gemcitabine Pregnancy and Breastfeeding Warnings. [Accessed 27 Mar. 2019] (online) Available from:
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Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
1. Product Introduction:
Vorier 200mg Tablet contains Voriconazole, a potent antifungal medication belonging to the triazole class of antifungals. It is primarily used to treat a variety of serious fungal infections that are unresponsive to other treatments. This medication works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, thus killing the fungi or stopping their growth.
Voriconazole is especially effective against invasive fungal infections, particularly in immunocompromised patients, such as those undergoing chemotherapy, organ transplants, or with HIV/AIDS. Vorier 200mg Tablet is administered under strict medical supervision, and dosage is usually tailored based on the patient’s medical history, liver function, and other concurrent treatments.
2. Uses of This Medicine:
Vorier 200mg Tablet is used in the treatment and prevention of serious fungal infections. The primary indications include:
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Invasive Aspergillosis:
A life-threatening infection caused by Aspergillus species, often seen in patients with weakened immune systems. -
Candidemia (Bloodstream Infections):
Caused by Candida species in non-neutropenic patients. -
Esophageal Candidiasis:
Fungal infection of the esophagus. -
Fungal Infections in the Skin, Lungs, and Other Organs:
Especially when the infection is resistant to other antifungal agents. -
Scedosporiosis and Fusariosis:
Rare but serious fungal infections. -
Prophylaxis in High-Risk Patients:
Voriconazole is often used to prevent fungal infections in patients undergoing organ transplantation or intensive chemotherapy.
3. Benefits of This Medicine:
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Broad-Spectrum Antifungal Coverage:
Effective against a wide range of fungi, including resistant strains of Candida and Aspergillus. -
Life-Saving in Immunocompromised Patients:
Essential for patients with severely weakened immune systems, helping prevent and treat deadly fungal infections. -
High Tissue Penetration:
Voriconazole penetrates well into tissues, including the brain, making it effective in treating central nervous system fungal infections. -
Oral and IV Availability:
Allows flexible dosing, switching between oral and intravenous forms based on patient condition. -
Well-Studied and Recommended:
Voriconazole is the first-line treatment for invasive aspergillosis and is supported by multiple clinical guidelines.
4. Side Effects:
While Vorier 200mg Tablet is highly effective, it may cause side effects in some patients. These range from mild to severe, and monitoring during treatment is important.
Common Side Effects:
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Nausea or vomiting
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Headache
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Visual disturbances (blurred vision, color perception changes)
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Rash
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Fever
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Diarrhea
Serious Side Effects:
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Liver Dysfunction:
Elevated liver enzymes or jaundice. Liver function tests are usually monitored during therapy. -
Skin Reactions:
Severe skin rashes, photosensitivity, or Stevens-Johnson syndrome (rare but serious). -
Neurological Effects:
Hallucinations, confusion, or seizures in some cases. -
Heart Rhythm Disorders:
Can cause QT interval prolongation, especially when taken with other interacting medications.
Always consult your doctor immediately if any unusual symptoms develop during treatment with Vorier 200mg.
5. Frequently Asked Questions (FAQ):
Q1. What is Vorier 200mg Tablet used for?
A: Vorier is used to treat serious fungal infections like invasive aspergillosis, candidemia, and infections caused by Scedosporium and Fusarium species, especially in immunocompromised individuals.Q2. How should I take Vorier 200mg Tablet?
A: Take the tablet at least one hour before or one hour after meals to ensure proper absorption. Follow the prescribed schedule and dosage as directed by your physician.Q3. Can Vorier be taken with food?
A: It is recommended to take Vorier on an empty stomach for better absorption. Food can reduce its effectiveness.Q4. Are there any precautions I should follow while on Vorier?
A: Yes. Avoid direct sunlight or tanning beds as Voriconazole can cause photosensitivity. Use sunscreen and protective clothing outdoors. Regular blood tests may be required to monitor liver function.Q5. Can I consume alcohol while taking Vorier?
A: It is best to avoid alcohol as both alcohol and Voriconazole can affect liver function.
References
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Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1580-81.
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Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 841.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1498-99.
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Voriconazole. Petersfield, Hampshire: Aspire Pharma Ltd.; 2015 [revised 27 Feb. 2019]. [Accessed 29 Mar. 2019] (online) Available from:
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Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:
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Voriconazole [Prescribing Information]. New York, NY: Pfizer; 2022. [Accessed 07 Aug. 2023]. (online) Available from:
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CiplaMed. Voriconazole [Prescribing Information]. [Last Updated: Oct. 2013] [Accessed 07 Aug. 2023]. (online) Available from:
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Shipping Policy
We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.
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