Clexane 60mg Injection

1. Product Introduction

Clexane 60mg Injection is an anticoagulant (blood thinner) used to prevent and treat the formation of harmful blood clots. It contains Enoxaparin, a low molecular weight heparin (LMWH) that helps reduce the risk of life-threatening conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), and heart attacks in patients with angina or heart disease.

Clexane is administered as a subcutaneous injection (under the skin), usually in the abdomen. It is used in hospitals before and after surgeries, during prolonged hospital stays, or in patients at risk for clot formation due to reduced mobility or underlying health issues.

The formulation of Enoxaparin in Clexane offers predictable and effective anticoagulant action with a lower risk of complications compared to traditional heparin.

2. Uses of Clexane 60mg Injection

Clexane 60mg is commonly prescribed in the following medical scenarios:

• Prevention of deep vein thrombosis (DVT):
  In patients undergoing orthopedic (hip/knee) or abdominal surgery, or those confined to bed due to illness.

• Treatment of deep vein thrombosis and pulmonary embolism (PE):
  Helps dissolve existing blood clots in the legs or lungs.

• Unstable angina and non-ST segment elevation myocardial infarction (NSTEMI):
  Reduces the risk of heart attacks by preventing clot formation in coronary arteries.

• ST-segment elevation myocardial infarction (STEMI):
  Used with other medications during acute heart attacks.

• Preventing clot formation in patients on dialysis:
  Clexane is used in certain cases to prevent clotting in the dialysis machine during hemodialysis.

• During pregnancy in selected high-risk women:
  Sometimes used under medical guidance to reduce risk of miscarriage or clot formation in pregnant women with clotting disorders.

3. Benefits of Clexane 60mg Injection

• Effective clot prevention:
  Clexane helps reduce the formation of blood clots in veins and arteries, lowering the risk of conditions like DVT, PE, and strokes.

• Fast-acting and long-lasting:
  The medication begins working shortly after injection and has a long half-life, allowing for once or twice daily dosing.

• Lower risk of bleeding complications:
  Compared to unfractionated heparin, Enoxaparin has a more stable and predictable anticoagulant effect, which minimizes the need for frequent blood monitoring.

• Safe in high-risk surgical patients:
  Proven to be effective in preventing postoperative thromboembolic events in orthopedic and abdominal surgery.

• Convenient administration:
  It is administered subcutaneously, which can sometimes be done at home under medical advice, improving patient compliance.

• Fewer hospital readmissions:
  By preventing clot-related complications, Clexane reduces the risk of rehospitalization, improving overall patient outcomes.

4. Side Effects

Like all medications, Clexane 60mg Injection may cause side effects, although not everyone experiences them. The most common side effects are related to bleeding.

Common Side Effects:

• Injection site reactions (pain, bruising, redness)

• Mild bleeding (from nose or gums)

• Easy bruising

Serious Side Effects:

• Major bleeding (internal bleeding, gastrointestinal bleeding)

• Low platelet count (thrombocytopenia)

• Allergic reactions (rash, itching, swelling)

• Elevated liver enzymes

• Hematoma (blood pooling under the skin or around the spinal cord if administered with spinal anesthesia)

Patients should inform their healthcare provider if they notice unusual bleeding, blood in urine/stools, or signs of allergic reactions. Individuals with a history of bleeding disorders, recent surgeries, or peptic ulcers must use this medication with caution.

5. Frequently Asked Questions (FAQ)

Q1. What is Clexane 60mg Injection used for?
A: Clexane is used to prevent and treat blood clots, particularly in patients after surgery, during prolonged immobility, or with heart conditions like angina and heart attacks.

Q2. How is Clexane administered?
A: It is injected subcutaneously (under the skin), usually in the abdominal area. It should not be administered into a muscle (intramuscularly).

Q3. How long does it take for Clexane to work?
A: Clexane starts working within 1 to 2 hours of injection, and its effects can last up to 12–24 hours, depending on the dosage and condition being treated.

Q4. Can I use Clexane at home?
A: Yes, in some cases, doctors may advise home administration. You or a caregiver will be trained to give the injection safely.

Q5. Is monitoring required while using Clexane?
A: Routine blood monitoring is generally not required with Enoxaparin unless the patient has kidney issues, is pregnant, or is at a high risk of bleeding.