

Dapmicin 350mg Injection
₹5,890.00 Original price was: ₹5,890.00.₹3,200.00Current price is: ₹3,200.00.
 Prescription Required
 Cold chain
Salt : Daptomycin (350mg)
Manufacturer : Glenmark Pharmaceuticals Ltd.
Packing : 1 Injection in 1 vial
Prepaid Only, Non-Returnab
1. Product Introduction
Dapmicin 350mg Injection is a powerful antibiotic medicine that contains the active ingredient Daptomycin (350mg). It belongs to the class of antibiotics known as lipopeptides and is primarily used to treat serious bacterial infections, especially those caused by gram-positive bacteria that are resistant to standard antibiotics.
This injection is administered intravenously (into a vein) under medical supervision, often in a hospital or clinical setting. Daptomycin works by disrupting the cell membrane of bacteria, causing them to die. It is highly effective against multi-drug resistant bacteria like Methicillin-Resistant Staphylococcus Aureus (MRSA) and Vancomycin-Resistant Enterococci (VRE).
Dapmicin 350mg is usually prescribed when other antibiotics are not effective or when a patient cannot tolerate other treatments. It is not effective for treating viral infections like the common cold or flu.
2. Uses of This Medicine
Dapmicin 350mg Injection is indicated for the treatment of the following serious bacterial infections:
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Complicated Skin and Skin Structure Infections (cSSSI): Includes infections such as cellulitis, abscesses, and wound infections caused by gram-positive bacteria.
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Bacteremia (Bloodstream Infections): Especially infections caused by Staphylococcus aureus, including MRSA strains.
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Right-Sided Infective Endocarditis: A heart infection often seen in intravenous drug users or patients with prosthetic valves, particularly caused by Staphylococcus aureus.
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Osteomyelitis (Bone Infections): Though not officially approved in all countries, Daptomycin is sometimes used off-label for deep-seated infections like bone infections.
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Septicemia: Life-threatening infections where bacteria enter the bloodstream and spread throughout the body.
3. Benefits of This Medicine
Dapmicin 350mg Injection offers several significant advantages in the treatment of life-threatening bacterial infections:
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Highly Effective Against Resistant Bacteria: It works well against bacteria that no longer respond to traditional antibiotics like methicillin or vancomycin.
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Rapid Bacterial Killing Action: Daptomycin kills bacteria by disrupting their cell membranes, leading to a faster resolution of infection.
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Once-Daily Dosing: Its long half-life allows for convenient once-daily administration, reducing hospital visits or inpatient time.
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Tissue Penetration: It reaches effective concentrations in skin, blood, and even heart tissues, making it suitable for complex infections.
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Safe Alternative in Case of Allergies: Dapmicin is often used when patients are allergic to beta-lactam antibiotics such as penicillins or cephalosporins.
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Lower Risk of Clostridioides difficile Infection: Compared to other broad-spectrum antibiotics, it has a relatively lower risk of causing secondary infections like C. difficile colitis.
4. Side Effects
Like all medicines, Dapmicin 350mg Injection may cause some side effects. Most are mild and manageable, but some may require medical attention.
Common Side Effects:
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Nausea or vomiting
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Headache
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Constipation or diarrhea
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Injection site reactions (pain, redness, or swelling)
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Muscle pain or weakness
Serious but Rare Side Effects:
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Myopathy (muscle damage): Symptoms include muscle pain, tenderness, or weakness. Regular monitoring of creatine phosphokinase (CPK) levels is advised.
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Eosinophilic Pneumonia: A rare lung condition presenting with cough, fever, and difficulty breathing. Immediate medical attention is required.
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Allergic Reactions: Rash, itching, swelling, dizziness, or trouble breathing (anaphylaxis).
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Peripheral Neuropathy: Tingling or numbness, particularly in hands and feet.
If any side effects become severe or persistent, patients should contact their healthcare provider immediately.
5. Frequently Asked Questions (FAQ)
Q1. What is Dapmicin 350mg Injection used for?
A: Dapmicin is used to treat serious bacterial infections like complicated skin infections, blood infections, and right-sided infective endocarditis caused by resistant bacteria.
Q2. How is this injection administered?
A: It is given as an intravenous (IV) infusion by a healthcare professional, usually once daily.
Q3. Can I take Dapmicin Injection at home?
A: In some cases, if you are stable and trained, you may receive Dapmicin through outpatient services or home healthcare, under close supervision. Do not attempt to self-administer unless advised by a doctor.
Q4. How long does it take for Dapmicin to work?
A: Some symptoms may start to improve within a few days, but full recovery can take several days to weeks depending on the severity of the infection. It is important to complete the full course as prescribed.
Q5. Is Dapmicin safe during pregnancy or breastfeeding?
A: The safety of Dapmicin in pregnancy and breastfeeding has not been fully established. It should only be used if clearly needed and prescribed by your doctor.
References
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MacDougall C, Chambers HF. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1543-44.
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Chambers HF, Deck DH. Beta-Lactam and Other Cell Wall- & Membrane-Active Antibiotics. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 787-88.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 357-58.
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Drugs.com. Daptomycin. [Accessed 28 Mar. 2019] (online) Available from:
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