

Dasatrue 70mg Tablet
₹9,350.00 Original price was: ₹9,350.00.₹3,800.00Current price is: ₹3,800.00.
 Prescription Required
Salt : Dasatinib (70mg)
Manufacturer : Cipla Ltd
Packing : 60Â tablets in 1 bottle
1. Product Introduction
Dasatrue 70mg Tablet is a targeted therapy used in the treatment of certain types of blood cancers. It contains the active ingredient Dasatinib (70mg), which belongs to a class of medications known as tyrosine kinase inhibitors (TKIs). Dasatinib works by blocking the action of abnormal proteins that signal cancer cells to grow. It is especially effective in treating leukemia where genetic mutations play a key role in disease progression.
Manufactured in high-quality pharmaceutical facilities, Dasatrue 70mg is a prescription medicine and must be taken under the strict guidance of an oncologist or hematologist. This tablet is formulated to be taken orally and is part of long-term treatment regimens aimed at controlling and potentially achieving remission in chronic blood cancers.
2. Uses of This Medicine
Dasatrue 70mg Tablet is used to treat specific forms of leukemia, a type of cancer that affects the blood and bone marrow. The key uses include:
🔹 Chronic Myeloid Leukemia (CML):
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Indicated for adults and children with Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia, especially in cases that are resistant or intolerant to prior therapy, including Imatinib.
🔹 Acute Lymphoblastic Leukemia (ALL):
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Used for Ph+ acute lymphoblastic leukemia, either as a standalone treatment or in combination with other chemotherapy drugs.
🔹 Accelerated and Blast Phase CML:
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Also effective in treating patients in the more advanced phases of chronic myeloid leukemia.
Dasatinib is often prescribed when other medications have failed or when a more potent response is needed to achieve remission and prevent disease progression.
3. Benefits of This Medicine
The benefits of Dasatrue 70mg Tablet lie in its ability to specifically target cancerous cells, making it an effective and preferred choice in treating certain blood cancers.
âś… Targeted Therapy:
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Dasatinib precisely blocks the BCR-ABL tyrosine kinase, the abnormal protein responsible for uncontrolled growth of white blood cells in leukemia.
âś… High Response Rate:
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Many patients achieve complete cytogenetic and molecular remission, especially those who start treatment early.
âś… Effective Against Resistant Leukemia:
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Works even in patients who have not responded well to first-line TKIs like Imatinib.
âś… Improves Survival:
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Significantly enhances progression-free survival and overall survival in CML and ALL patients.
âś… Convenient Oral Dosing:
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Taken as a once-daily oral tablet, it offers ease of administration without the need for hospital-based infusion.
âś… Pediatric Indication:
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Can be used safely in children with Ph+ leukemia under medical supervision, making it a valuable option across age groups.
4. Side Effects
Like all potent anti-cancer medicines, Dasatrue 70mg may cause some side effects. These can range from mild to serious and may require dose adjustment or supportive care.
Common Side Effects:
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Headache
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Fatigue
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Nausea or vomiting
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Diarrhea
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Abdominal pain
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Skin rash
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Muscle or joint pain
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Fluid retention (swelling in the hands, feet, or around eyes)
Serious Side Effects (Require Immediate Attention):
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Shortness of breath (due to pleural effusion or fluid in lungs)
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Low blood cell counts (anemia, low platelets, neutropenia)
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Bleeding or bruising easily
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Infections due to reduced immunity
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Irregular heartbeat or chest pain
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Liver dysfunction (elevated liver enzymes)
Patients are monitored closely during therapy through regular blood tests and imaging, and treatment is adjusted based on tolerance and response.
5. Frequently Asked Questions (FAQ)
Q1. What is Dasatrue 70mg Tablet used for?
A: Dasatrue is primarily used to treat Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) and acute lymphoblastic leukemia (Ph+ ALL) in both adults and children.
Q2. How does Dasatinib work?
A: Dasatinib blocks the BCR-ABL protein, which is produced by a specific genetic mutation (Philadelphia chromosome) in leukemia patients. Blocking this protein stops cancer cells from growing.
Q3. Can Dasatrue cure leukemia?
A: While not always a cure, Dasatrue can help achieve deep remission, meaning the cancer becomes undetectable in many patients. Some may continue long-term therapy, while others may eventually stop treatment under medical guidance.
Q4. How should I take this medicine?
A: Take Dasatrue 70mg Tablet as prescribed by your doctor. It is usually taken once daily with or without food, swallowed whole with water.
Q5. What if I miss a dose?
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your schedule. Do not double the dose.
References
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Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1732-34.
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Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 953.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 361-62.
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