

Decintas 30mg Injection
₹3,918.00 Original price was: ₹3,918.00.₹2,550.00Current price is: ₹2,550.00.
 Prescription Required
Salt : Decitabine (30mg)
Manufacturer : Intas Pharmaceuticals Ltd
Packing : 1 Injection in 1 vial
1. Product Introduction
Decintas 30mg Injection contains Decitabine, a powerful anticancer medication used in the treatment of specific blood cancers. Decitabine belongs to a class of drugs called hypomethylating agents, which help in reactivating genes that have been silenced in cancer cells, thereby slowing or stopping the growth of the cancer.
This injection is administered intravenously by a healthcare professional, usually in a hospital or specialized clinic setting. It works at the cellular level by altering DNA, leading to changes in how cancer cells grow and divide. The treatment is often part of a chemotherapy regimen and is used in cycles, with rest periods in between.
Decintas 30mg Injection is considered an important treatment option for myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) in adults who are not candidates for standard intensive chemotherapy.
2. Uses of This Medicine
Decintas 30mg Injection is used primarily for the treatment of hematological (blood-related) cancers. The key medical uses include:
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Myelodysplastic Syndromes (MDS): A group of disorders caused by poorly formed or dysfunctional blood cells, which can evolve into leukemia.
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Acute Myeloid Leukemia (AML): A fast-growing cancer of the blood and bone marrow that requires immediate treatment.
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Chronic Myelomonocytic Leukemia (CMML): A rare type of leukemia that combines features of MDS and myeloproliferative disorders.
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Other related bone marrow disorders: Based on physician evaluation and patient response.
It is typically used in older adults or patients who cannot tolerate more aggressive treatments, providing a less intensive but effective therapeutic alternative.
3. Benefits of This Medicine
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Effective Cancer Control: Decitabine works at the genetic level to help slow down or stop the uncontrolled growth of abnormal blood cells in cancers like MDS and AML.
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Improves Bone Marrow Function: By helping the bone marrow produce healthy blood cells, it can reduce symptoms such as anemia, infections, and bleeding tendencies.
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Disease Stabilization: In some patients, Decintas helps control disease progression and improve quality of life, especially when used early in disease.
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Alternative to Intensive Chemotherapy: Suitable for patients who are elderly or unfit for aggressive chemotherapy regimens.
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Potential to Delay Disease Progression: Helps delay the need for blood transfusions and disease-related complications.
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Well-Studied and FDA Approved: The active ingredient, Decitabine, has undergone extensive clinical trials and is approved for medical use in multiple countries.
4. Side Effects
Like all chemotherapy drugs, Decintas 30mg Injection can cause side effects. These can vary depending on the patient’s health status, dosage, and individual response to the medicine.
Common Side Effects:
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Low blood cell counts (anemia, neutropenia, thrombocytopenia)
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Fatigue or weakness
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Fever and infections
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Nausea and vomiting
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Loss of appetite
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Constipation or diarrhea
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Cough and breathing difficulty
Serious Side Effects:
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Severe infections (due to reduced immunity)
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Bleeding or bruising (from low platelet counts)
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Liver function changes
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Allergic reactions (rash, itching, swelling, difficulty breathing)
Patients on Decintas require frequent blood tests to monitor blood cell counts and liver/kidney functions. Supportive care such as antibiotics, antifungals, or blood transfusions may be necessary during treatment.
If severe side effects or unusual symptoms occur, it is essential to seek medical help immediately.
5. Frequently Asked Questions (FAQ)
Q1. What is Decintas 30mg Injection used for?
A: It is used to treat myelodysplastic syndromes (MDS), acute myeloid leukemia (AML), and other blood-related cancers, especially in adults who are not suitable for high-dose chemotherapy.
Q2. How is this medicine given?
A: Decintas is administered through an intravenous (IV) infusion by a trained healthcare professional in a clinical setting. It is given in cycles, which may include several days of treatment followed by rest periods.
Q3. Can I take this injection at home?
A: No. This injection should only be administered under the supervision of a doctor or a chemotherapy nurse in a hospital or clinic, due to the risk of side effects and the need for close monitoring.
Q4. Is it safe during pregnancy or breastfeeding?
A: No. Decitabine can harm the unborn baby and is not recommended during pregnancy or breastfeeding. Women of childbearing potential should use effective contraception during and after treatment.
Q5. How long will I need to take this medicine?
A: The number of treatment cycles depends on how well your body responds to the medicine. Your doctor will determine the exact duration based on your medical condition and progress.
References
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 364.
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Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
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