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Eltrog 25mg Tablet

Original price was: ₹800.00.Current price is: ₹700.00.

  Prescription Required

Salt : Eltrombopag

Manufacturer : GLENMARK PHARMACEUTICALS LTD

Packing : 7 Tablet(S) In A Strip

Description

1. Product Introduction

Eltrog 25mg Tablet is a prescription medication that contains the active ingredient Eltrombopag, which belongs to a class of drugs called thrombopoietin receptor agonists. It is used to increase platelet production in the blood, especially in patients with specific platelet-deficiency disorders.

Eltrombopag works by stimulating the bone marrow to produce more platelets, which are essential for blood clotting. Low platelet counts can lead to excessive bleeding or bruising and may be life-threatening if not treated. Eltrog is commonly used in conditions like chronic immune thrombocytopenia (ITP), hepatitis C-associated thrombocytopenia, and severe aplastic anemia.

This tablet is usually taken orally once daily on an empty stomach or as directed by the physician. Eltrog should be used under strict medical supervision due to its potential side effects and need for regular blood monitoring.


2. Uses of Eltrog 25mg Tablet

Eltrog 25mg is used in the treatment of the following conditions:

  • Chronic Immune Thrombocytopenic Purpura (ITP):
    In patients who have not responded adequately to other treatments such as corticosteroids or splenectomy, Eltrog helps increase platelet counts and reduce bleeding episodes.

  • Thrombocytopenia in Hepatitis C Patients:
    For patients receiving interferon-based therapy for chronic hepatitis C, Eltrog helps manage low platelet levels, enabling continuation of antiviral treatment.

  • Severe Aplastic Anemia (SAA):
    It is used in patients with acquired aplastic anemia who do not respond to immunosuppressive therapy. Eltrombopag stimulates blood cell production in such cases.

These indications make Eltrog an important therapy for patients at risk of severe bleeding due to low platelet counts, especially when other treatments have failed or are not suitable.


3. Benefits of Eltrog 25mg Tablet

  • Improves Platelet Counts:
    The primary benefit of Eltrog is its ability to safely increase platelet production, reducing the risk of spontaneous bleeding.

  • Enables Continuation of Hepatitis C Therapy:
    Thrombocytopenia is a common side effect of interferon treatment. Eltrog helps maintain platelet levels so patients can complete antiviral regimens.

  • Alternative for Non-Responders:
    It offers a valuable treatment option for patients unresponsive to steroids, immunoglobulin therapy, or surgery (splenectomy).

  • Reduces Bleeding Episodes:
    Patients with chronic ITP often suffer from nosebleeds, gum bleeding, and internal bleeding. Eltrog reduces these events significantly.

  • Supports Recovery in Aplastic Anemia:
    In SAA, it not only boosts platelets but may also enhance red and white blood cell counts, improving overall hematologic function.

  • Oral and Convenient:
    Being an oral tablet, Eltrog is easy to administer, especially when compared to injectable platelet-boosting agents.

Overall, Eltrog improves quality of life and safety for patients with low platelet disorders.


4. Side Effects

While Eltrog 25mg Tablet is generally effective and well-tolerated, some patients may experience side effects. Common and serious side effects include:

Common Side Effects:

  • Nausea

  • Diarrhea

  • Headache

  • Fatigue

  • Muscle pain

  • Upper respiratory tract infection

  • Increased liver enzyme levels

Serious Side Effects:

  • Liver toxicity: Elevation of liver enzymes (ALT, AST) or bilirubin may occur. Regular liver function tests are recommended.

  • Thromboembolic events: Eltrog can sometimes increase the risk of blood clots (e.g., DVT, pulmonary embolism).

  • Cataract formation: In rare cases, long-term use may increase the risk of cataracts.

  • Bone marrow fibrosis: Chronic use can lead to scarring in the bone marrow, which affects blood cell production.

Always inform your doctor if you notice symptoms like yellowing of the skin or eyes (jaundice), chest pain, leg swelling, vision changes, or unusual bruising/bleeding. Regular monitoring of blood counts and liver function is essential during treatment.


5. Frequently Asked Questions (FAQ)

Q1. What is Eltrog 25mg used for?
A: Eltrog is used to treat low platelet counts in patients with chronic ITP, hepatitis C-related thrombocytopenia, and severe aplastic anemia.

Q2. How does Eltrog work?
A: It works by stimulating the thrombopoietin receptor on bone marrow cells, encouraging them to produce more platelets and reduce bleeding risk.

Q3. When should I take Eltrog?
A: Eltrog should be taken at least 1–2 hours before or 4 hours after meals containing calcium or minerals, as these can interfere with absorption. Take it at the same time each day as prescribed.

Q4. Is Eltrog safe for long-term use?
A: It can be used long-term under supervision, but regular monitoring of liver function and blood cell counts is necessary to avoid complications.

Q5. Can I stop taking Eltrog once my platelets increase?
A: No, stopping the medication suddenly may cause platelet levels to drop. Your doctor will guide any dose adjustments or discontinuation based on your condition.


References

  1. Eltrombopag. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2008 [revised Nov. 2018]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  2. Eltrombopag. Research Triangle Park, NC: GlaxoSmithKline; 2014. [Accessed 07 Apr. 2019] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 07 Apr. 2019] (online) Available from:External Link


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