Esentra 120 Injection

Product Introduction

Esentra 120 Injection is a prescription-based medication that contains Denosumab (120mg) as its active ingredient. It belongs to a class of drugs known as monoclonal antibodies, which are designed to target specific proteins in the body. Denosumab works by inhibiting the activity of osteoclasts, the cells responsible for breaking down bone tissue. This makes Esentra 120 Injection an effective treatment for conditions related to bone loss and skeletal health.

Esentra 120 Injection is primarily used to treat osteoporosis in postmenopausal women at high risk of fractures, bone loss due to hormone ablation in men with prostate cancer, and giant cell tumor of bone. It is administered as a subcutaneous injection (under the skin) by a healthcare professional. The medication is available in a pre-filled syringe, ensuring ease of use and accurate dosing.

Uses of Esentra 120 Injection

Esentra 120 Injection is prescribed for the following conditions:

• Postmenopausal Osteoporosis: It helps strengthen bones and reduce the risk of fractures in women who have undergone menopause and are at high risk of bone loss.
• Bone Loss in Men with Prostate Cancer: Men undergoing hormone therapy for prostate cancer often experience bone loss. Esentra 120 Injection helps prevent this bone loss and reduces the risk of fractures.
• Giant Cell Tumor of Bone: This rare, non-cancerous tumor can weaken bones. Esentra 120 Injection helps inhibit the growth of these tumors and prevents bone destruction.
• Hypercalcemia of Malignancy: In some cancer patients, high calcium levels in the blood (hypercalcemia) can occur due to bone breakdown. Esentra 120 Injection helps manage this condition by reducing bone resorption.

Benefits of Esentra 120 Injection

Esentra 120 Injection offers several benefits for patients with bone-related conditions:

• Reduces Fracture Risk: By increasing bone density, Esentra 120 Injection significantly lowers the risk of fractures, particularly in postmenopausal women and cancer patients.
• Improves Bone Strength: The medication helps maintain bone integrity, making bones stronger and less prone to damage.
• Convenient Dosage: Esentra 120 Injection is administered as a single subcutaneous injection every six months, making it a convenient treatment option compared to daily medications.
• Effective for Cancer Patients: It helps manage bone loss and hypercalcemia in patients undergoing cancer treatment, improving their quality of life.
• Non-Hormonal Treatment: Unlike some osteoporosis treatments, Esentra 120 Injection does not contain hormones, making it suitable for patients who cannot take hormone-based therapies.

Side Effects of Esentra 120 Injection

While Esentra 120 Injection is effective, it may cause some side effects. These side effects can vary from mild to severe and may include:

Common Side Effects:

• Pain, swelling, or redness at the injection site
• Fatigue or weakness
• Back pain
• Joint or muscle pain
• Nausea or diarrhea
• Cold-like symptoms (e.g., runny nose, sore throat)

Serious Side Effects:

• Hypocalcemia (low calcium levels): Symptoms include muscle cramps, numbness, tingling, or seizures. Calcium and vitamin D supplements are often prescribed to prevent this.
• Osteonecrosis of the Jaw (ONJ): A rare but serious condition where the jawbone fails to heal properly, leading to bone damage. Good oral hygiene and regular dental check-ups can help reduce this risk.
• Atypical Femur Fractures: Long-term use of Esentra 120 Injection may increase the risk of unusual fractures in the thigh bone.
• Infections: There is a slight risk of serious infections due to the immune-suppressing effects of Denosumab.

If you experience any severe side effects, contact your healthcare provider immediately. It is essential to discuss your medical history and any ongoing medications with your doctor before starting Esentra 120 Injection to minimize the risk of adverse effects.

Frequently Asked Questions (FAQ)

Q1. How is Esentra 120 Injection administered?

Esentra 120 Injection is given as a subcutaneous injection, usually in the upper arm, thigh, or abdomen. It is administered by a healthcare professional every six months.

Q2. Can I take Esentra 120 Injection during pregnancy?

No, Esentra 120 Injection is not recommended during pregnancy as it may harm the developing fetus. Inform your doctor if you are pregnant or planning to become pregnant.

Q3. What should I do if I miss a dose?

If you miss a scheduled dose, contact your healthcare provider as soon as possible to reschedule. Do not double the dose to make up for the missed one.

Q4. Can I take calcium and vitamin D supplements with Esentra 120 Injection?

Yes, your doctor may recommend calcium and vitamin D supplements to prevent hypocalcemia (low calcium levels) while on Esentra 120 Injection.

Q5. How long does it take for Esentra 120 Injection to show results?

Improvement in bone density can be observed within a few months of starting treatment. However, the full benefits may take up to a year or more, depending on the individual.