Geftin 250mg Tablet

1. Product Introduction

Geftin 250mg Tablet contains Gefitinib, a targeted cancer therapy belonging to the class of drugs known as tyrosine kinase inhibitors (TKIs). Gefitinib is specially designed to block certain proteins (specifically, the epidermal growth factor receptor or EGFR) that signal cancer cells to grow and divide. By blocking this receptor, Gefitinib helps slow down or stop the spread of cancer cells.

Manufactured for oral use, Geftin 250mg provides a convenient alternative to intravenous chemotherapy. It is mainly prescribed for patients with non-small cell lung cancer (NSCLC), particularly those whose tumors have specific mutations in the EGFR gene. Its precision in targeting cancer cells makes it a significant advancement over traditional chemotherapy, often resulting in fewer side effects and better patient outcomes.

2. Uses of Geftin 250mg Tablet

Geftin 250mg Tablet is primarily indicated for:

• Non-Small Cell Lung Cancer (NSCLC):
  It is prescribed for the treatment of locally advanced or metastatic NSCLC, especially for patients whose tumors show EGFR mutations.
  It can be used:

  • As a first-line treatment.

  • After failure of chemotherapy.

  • In maintenance therapy to prevent disease progression.

• Off-label uses (under specialist advice):
  Gefitinib may also be considered in other types of cancers that show overexpression of EGFR, although its primary and approved use remains in NSCLC.

Patients are usually required to undergo a specific genetic test to check for EGFR mutations before starting therapy with Gefitinib.

3. Benefits of Geftin 250mg Tablet

• Targeted Action:
  Gefitinib acts specifically on cancer cells with EGFR mutations, minimizing damage to healthy cells compared to traditional chemotherapy.

• Improved Survival Rates:
  Clinical studies show that patients with EGFR mutations respond better and have longer progression-free survival with Gefitinib compared to standard chemotherapy.

• Convenient Oral Administration:
  Being a tablet, it can be taken at home, reducing the need for hospital visits for intravenous chemotherapy sessions.

• Fewer Severe Side Effects:
  Compared to conventional chemotherapy, Gefitinib tends to cause less severe nausea, vomiting, and hair loss.

• Better Quality of Life:
  Due to its milder side effect profile, patients on Geftin 250mg often maintain a better quality of life during treatment.

• Rapid Symptom Relief:
  Many patients experience a quick reduction in symptoms like cough, breathing difficulties, and chest pain after starting Gefitinib.

• Use in Maintenance Therapy:
  It helps in controlling cancer and delaying progression after the initial success of chemotherapy.

4. Side Effects of Geftin 250mg Tablet

While Geftin 250mg is usually well-tolerated, some patients may experience side effects. It is important to discuss and manage them with the treating oncologist.

Common Side Effects:

• Skin rash

• Diarrhea

• Dry skin

• Nausea

• Vomiting

• Loss of appetite

• Weakness and fatigue

• Mouth sores

Serious Side Effects (Less Common):

• Interstitial lung disease (rare but serious lung inflammation)

• Liver dysfunction (abnormal liver function tests)

• Severe diarrhea leading to dehydration

• Eye problems like conjunctivitis or dry eyes

Important Points:

• Routine liver function tests are recommended during treatment.

• Notify the doctor immediately if experiencing breathing difficulties, persistent diarrhea, severe skin rash, or yellowing of the skin/eyes (jaundice).

• Dosage adjustments or temporary stoppage may be needed if serious side effects occur.

Precautions:

• Not recommended during pregnancy or breastfeeding.

• Effective contraception should be used during and for some time after treatment.

• Patients with a history of lung disease should be monitored closely.

5. Frequently Asked Questions (FAQ)

Q1. How should I take Geftin 250mg Tablet?
Take one tablet once daily, with or without food, at the same time each day. Swallow the tablet whole with water, and do not crush or chew it.

Q2. How long will I need to take Geftin 250mg?
Treatment duration depends on how well you respond to the medication and how you tolerate it. Some patients continue therapy for months or even years under regular monitoring.

Q3. Can Geftin 250mg cure lung cancer?
Geftinib is not considered a cure. However, it can significantly control disease progression, shrink tumors, and extend survival, especially in patients with EGFR-mutated lung cancer.

Q4. What if I miss a dose?
If you miss a dose, take it as soon as you remember. If it is close to the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q5. Will my hair fall out with Geftin 250mg?
Hair loss is not a common side effect with Geftin 250mg, unlike with traditional chemotherapy. Some patients may experience minor hair thinning.