Glenza 40mg Capsule (28)

1. Product Introduction

Glenza 40mg Capsule is an advanced oral medication that contains Enzalutamide, a next-generation androgen receptor inhibitor used in the treatment of prostate cancer. It is a hormonal therapy that works by blocking the effect of male hormones (androgens) like testosterone, which are known to stimulate the growth of prostate cancer cells.

This capsule is prescribed for adult male patients with metastatic castration-resistant prostate cancer (mCRPC) and non-metastatic castration-resistant prostate cancer (nmCRPC). Glenza helps in slowing down the growth and spread of the disease when traditional hormone therapies are no longer effective.

Enzalutamide is considered a major advancement in prostate cancer care due to its ability to target the cancer more precisely and improve survival outcomes without the need for chemotherapy.

2. Uses of This Medicine

Glenza 40mg Capsule is mainly used in the following clinical settings:

• Metastatic Castration-Resistant Prostate Cancer (mCRPC):
  For patients whose prostate cancer has spread to other parts of the body and continues to grow despite hormone therapy or surgical castration.

• Non-Metastatic Castration-Resistant Prostate Cancer (nmCRPC):
  For patients whose cancer has not yet spread but is no longer responding to treatments that lower testosterone levels.

• Combination with Other Treatments:
  Sometimes used along with luteinizing hormone-releasing hormone (LHRH) analogs or after surgical castration (orchiectomy) to maximize hormonal blockade.

3. Benefits of This Medicine

Glenza (Enzalutamide) offers several important benefits in managing prostate cancer effectively:

• Powerful Androgen Blockade:
  Enzalutamide blocks androgen receptors more effectively than older hormone therapies, preventing cancer cells from receiving growth signals.

• Improved Overall Survival:
  Clinical trials have shown that Glenza significantly extends survival in patients with advanced prostate cancer.

• Delays Disease Progression:
  Helps in delaying the need for chemotherapy and the worsening of cancer-related symptoms.

• Reduces PSA Levels:
  Enzalutamide lowers prostate-specific antigen (PSA) levels, an important marker of prostate cancer activity.

• Oral Administration:
  Being an oral capsule, Glenza offers convenience over intravenous therapies and can be taken at home under medical guidance.

• Better Quality of Life:
  By managing symptoms such as bone pain, fatigue, and urinary problems, it improves the patient’s comfort and quality of life.

4. Side Effects

Like all potent medications, Glenza 40mg Capsule may cause some side effects. While not everyone experiences them, it’s important to be aware and consult your doctor if they become severe or persistent.

Common Side Effects:

• Fatigue or tiredness

• Hot flashes

• Weakness

• Back pain or joint pain

• High blood pressure

• Constipation

• Headache

• Diarrhea

Serious Side Effects (Seek Immediate Medical Help):

• Seizures (although rare)

• Falls and fractures (due to muscle weakness or dizziness)

• Cognitive problems (such as memory issues, confusion)

• Increased risk of infections

• Heart-related complications (palpitations, chest pain)

Regular follow-ups and blood tests may be required to monitor your health during treatment with Enzalutamide.

5. Frequently Asked Questions (FAQ)

Q1. What is Glenza 40mg Capsule used for?
A: Glenza is used to treat advanced prostate cancer that is resistant to standard hormone-lowering therapies. It helps in slowing the progression of the disease and improving survival.

Q2. How does Enzalutamide work?
A: Enzalutamide is an androgen receptor inhibitor that blocks the action of male hormones (androgens) such as testosterone, which fuels the growth of prostate cancer cells.

Q3. How should I take Glenza?
A: Glenza should be taken once daily with or without food at the same time every day. Swallow the capsule whole with water. Do not crush or chew it.

Q4. Can Glenza be taken along with other medications?
A: Glenza may interact with certain medications, especially those affecting liver enzymes. Always inform your doctor about all other medicines or supplements you are taking.

Q5. What happens if I miss a dose?
A: If you miss a dose, take it as soon as you remember the same day. If it’s the next day, skip the missed dose—do not double dose to make up for it.

References

1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 474-75.
2. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
3. Enzalutamide. Netherlands: Astellas Pharma Europe B.V.; [Accessed on 27 Mar. 2019] (online) Available from:
4. PubChem. Enzalutamide. [Accessed 27 Mar. 2019] (online) Available from:

5. CiplaMed. Enzalutamide [Prescribing Information]. 2022. [Accessed 20 Feb. 2024] (online) Available from: 

   ---

   Disclaimer

   Online Medicos primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on  Online Medicos Our mission is to support, not replace, the doctor-patient relationship.