Gliotem 100mg Capsule

1. Product Introduction

Gliotem 100mg Capsule contains Temozolomide as its active ingredient. It belongs to a class of medicines called alkylating agents, which are primarily used in cancer treatment. Temozolomide works by damaging the DNA of cancer cells, preventing their growth and eventually leading to their death. It is an oral chemotherapy medication specifically designed for the treatment of certain types of brain tumors.

Gliotem is usually prescribed in combination with other treatments like surgery or radiation therapy, or sometimes used alone based on the patient’s condition. Since it is taken by mouth, it offers a convenient alternative to injectable chemotherapy options. Gliotem must be used under the supervision of an oncologist with regular monitoring of blood counts and organ functions to ensure safe and effective treatment.

2. Uses of Gliotem 100mg Capsule

Gliotem 100mg Capsule is mainly used in the treatment of brain cancers, specifically:

• Newly Diagnosed Glioblastoma Multiforme (GBM):
  Used alongside radiotherapy and then as maintenance therapy afterward to prolong survival.

• Recurrent Anaplastic Astrocytoma:
  For patients whose brain tumor has returned after initial treatment with other therapies.

• Other High-Grade Brain Tumors:
  Sometimes prescribed off-label for other aggressive brain cancers as determined by the oncologist.

Gliotem works by slowing down or stopping the growth of cancerous cells in the brain, offering a crucial option in managing aggressive brain tumors.

3. Benefits of Gliotem 100mg Capsule

• Convenient Oral Chemotherapy:
  Gliotem is available as a capsule, allowing patients to take it at home without the need for hospital-based chemotherapy infusions.

• Effective Against Aggressive Brain Tumors:
  It plays a significant role in prolonging survival and delaying the progression of high-grade brain cancers.

• Can Cross the Blood-Brain Barrier:
  Unlike many chemotherapies, Temozolomide is specially designed to cross the blood-brain barrier, making it particularly effective against brain tumors.

• Combination Treatment Advantage:
  When used alongside radiotherapy, Gliotem has shown better outcomes compared to radiotherapy alone.

• Flexibility in Treatment Plans:
  Oncologists can adjust the dosing schedules based on patient tolerance and response, allowing for personalized treatment approaches.

• Improves Quality of Life:
  By managing tumor growth and symptoms, Gliotem helps patients maintain a better quality of life during treatment.

4. Side Effects of Gliotem 100mg Capsule

While Gliotem is an effective medication, it can cause side effects, just like any cancer therapy. Some are mild, while others may require medical attention.

Common Side Effects:

• Nausea and vomiting

• Loss of appetite

• Fatigue and weakness

• Hair loss (usually mild)

• Constipation

• Headache

Serious Side Effects:

• Low blood cell counts (anemia, neutropenia, thrombocytopenia)
  → May lead to increased risk of infections, bleeding, and fatigue.

• Liver function abnormalities

• Severe skin reactions

• Pneumonitis (lung inflammation)

• Rare risk of secondary cancers like leukemia

Important Monitoring:

• Frequent blood tests to monitor blood cell counts and liver function are necessary during Gliotem therapy.

• Your doctor may adjust the dose or temporarily stop treatment depending on your body’s response.

Precautions:

• Inform your doctor if you have a history of liver problems, infections, or weakened immunity.

• Use effective contraception during and for several months after treatment, as Temozolomide can harm an unborn baby.

5. Frequently Asked Questions (FAQ)

Q1. How should I take Gliotem 100mg Capsule?
Take Gliotem exactly as prescribed by your oncologist. It is usually taken once daily on an empty stomach or as directed. Swallow the capsule whole with a glass of water—do not crush, chew, or open it.

Q2. How long will I have to take Gliotem?
The duration of treatment depends on your type of tumor, response to therapy, and your tolerance to the medicine. Your doctor will guide you on the specific treatment plan, often starting with a few cycles followed by reassessment.

Q3. What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember, unless it is almost time for the next dose. Do not double up doses. Inform your doctor about any missed doses for proper advice.

Q4. Can Gliotem cause infertility?
Yes, Gliotem may affect fertility in both men and women. It is important to discuss fertility preservation options with your doctor before starting treatment if you are planning to have children in the future.

Q5. What foods should I avoid while taking Gliotem?
There are no specific foods you must avoid, but since Gliotem can cause nausea, eating small, frequent meals and avoiding greasy or spicy foods may help. Also, maintain proper hydration.