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Glioz 100mg Capsule

Original price was: ₹7,534.00.Current price is: ₹2,600.00.

  Prescription Required

Salt : Temozolomide (100mg)

Manufacturer : Dr Reddy’s Laboratories Ltd

Packing : 5 Capsule(s) in Bottle

Description

1. Product Introduction

Glioz 100mg Capsule is an oral chemotherapy medicine containing Temozolomide, which belongs to the class of alkylating agents. It is primarily used to treat certain types of brain tumors, including glioblastoma multiforme and anaplastic astrocytoma. These are aggressive cancers of the central nervous system and require specialized treatment.

Temozolomide works by interfering with the DNA of cancer cells, preventing them from growing and multiplying. It can be used alone or in combination with other therapies like radiotherapy or other chemotherapeutic agents, depending on the stage and nature of the tumor.

Glioz provides a targeted approach with oral convenience, making it a preferred option for many patients and oncologists in managing high-grade brain tumors.


2. Uses of this Medicine

Glioz 100mg Capsule is prescribed for the treatment of:

  • Glioblastoma Multiforme (GBM) – the most common and aggressive form of primary brain cancer. Temozolomide is used both during radiotherapy and as maintenance therapy afterward.

  • Anaplastic Astrocytoma – a rare and malignant brain tumor where Glioz is often used after the failure of prior therapies.

  • Other high-grade gliomas, as determined by the oncologist.

In some cases, it may also be considered in clinical settings for other brain tumors, as per emerging evidence or trial protocols.


3. Benefits of this Medicine

  • Effective Brain Tumor Management: Glioz helps shrink brain tumors and control their growth, especially in aggressive cancers like glioblastoma.

  • Oral Convenience: Unlike many chemotherapy drugs that require intravenous infusion, Glioz can be taken by mouth, providing flexibility and ease of use.

  • Improves Survival Rates: When used as part of a standard treatment protocol, Glioz has been shown to extend both progression-free and overall survival in patients with GBM.

  • Synergistic with Radiotherapy: It enhances the effect of radiation therapy when used concurrently, increasing its effectiveness against tumor cells.

  • Less Invasive: Patients can often take this medicine from home, reducing hospital visits and allowing more independence during treatment.


4. Side Effects

Like all anti-cancer medications, Glioz 100mg Capsule may cause side effects. Most side effects are manageable and temporary, but some may require medical attention.

Common Side Effects:

  • Nausea and vomiting

  • Fatigue

  • Headache

  • Constipation

  • Loss of appetite

  • Hair thinning

  • Skin rash

Serious Side Effects:

  • Low white blood cell count (neutropenia) – leading to increased risk of infections

  • Thrombocytopenia (low platelet count) – which may cause easy bruising or bleeding

  • Anemia

  • Severe allergic reactions (rare)

  • Pneumonia (in patients with weakened immune systems)

Precautions:

  • Regular blood tests are essential to monitor blood cell counts during treatment.

  • Avoid people with infections as your immune system may be weakened.

  • Inform your doctor if you experience fever, unexplained bruising, or signs of bleeding.


5. Frequently Asked Questions (FAQ)

Q1. What is Glioz 100mg Capsule used for?
A: Glioz is used in the treatment of brain tumors such as glioblastoma multiforme and anaplastic astrocytoma, either alone or with radiation therapy.

Q2. How does Glioz work?
A: Glioz contains Temozolomide, which damages the DNA of cancer cells, stopping their ability to divide and grow. This leads to the death of tumor cells.

Q3. How should I take Glioz 100mg Capsule?
A: Take Glioz exactly as prescribed by your oncologist. It is usually taken once daily on an empty stomach (at least 1 hour before or 2 hours after meals). Swallow the capsule whole with water, without opening or crushing it.

Q4. Can Glioz be taken with food?
A: It is recommended to take Glioz on an empty stomach to maximize absorption and reduce the chance of nausea.

Q5. What happens if I miss a dose?
A: If you forget a dose, take it as soon as you remember on the same day. Do not take two doses the next day. Consult your doctor for further guidance.


References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1687.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1324-25.
  3. Temozolomide. Whitehouse Station, New Jersey: Merck & Co., Inc.; 1999 [revised Sep. 2015]. [Accecssed 25 Jan. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Temozolamide. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:External Link


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We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

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