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Halaven 1mg Injection

Original price was: ₹31,885.00.Current price is: ₹17,500.00.

  Prescription Required

Salt : Eribulin Mesylate (1mg)

Manufacturer : Eisai Pharmaceuticals India Pvt Ltd

Packing : 2 ml in 1 vial

Description

1. Product Introduction

Halaven 1mg Injection is a prescription anticancer medication used for the treatment of certain types of advanced or metastatic cancers. It contains Eribulin Mesylate, a synthetic analog of halichondrin B (a natural substance derived from marine sponges), and works as a microtubule inhibitor. This action helps stop the growth and spread of cancer cells by interfering with the structure and function of microtubules, which are essential for cell division.

Halaven is particularly indicated for patients with metastatic breast cancer who have already received multiple rounds of chemotherapy. It is also used for advanced liposarcoma, a rare type of soft tissue cancer. It is administered by a healthcare professional through intravenous (IV) infusion under strict medical supervision.

As a late-line chemotherapy option, Halaven offers renewed hope for patients who have not responded well to previous treatments. It may be used alone or in combination with other therapies, depending on the cancer type and stage.


2. Uses of this medicine

Halaven 1mg Injection is used in the treatment of:

  • Metastatic Breast Cancer
    For women whose breast cancer has spread to other parts of the body and who have previously received at least two chemotherapeutic regimens (including an anthracycline and a taxane).

  • Advanced or Metastatic Liposarcoma
    For adult patients who have received prior anthracycline-containing therapy and require additional treatment options.

  • Other Solid Tumors (Off-label use under clinical supervision)
    May be used in rare cases where conventional treatments have failed and based on oncologist’s discretion.


3. Benefits of this medicine

  • Effective Against Drug-Resistant Cancer Cells
    Halaven works differently from conventional chemotherapy drugs, making it effective in patients who have developed resistance to other treatments.

  • Delays Disease Progression
    Clinical trials have shown that Halaven significantly prolongs progression-free survival and overall survival in patients with metastatic cancers.

  • Promotes Apoptosis (Cell Death)
    Apart from stopping cell division, Eribulin also promotes apoptosis, leading to the natural death of cancer cells.

  • Improves Quality of Life
    By reducing tumor burden and associated symptoms, Halaven helps patients regain some level of normalcy in daily life activities.

  • Minimal Cross-Resistance
    Since it has a unique mechanism, Halaven shows limited cross-resistance with other chemotherapeutic agents, making it suitable for late-stage treatment.

  • Hope for Advanced Cancers
    For patients with few remaining options, Halaven can be a life-extending therapy with manageable side effects under expert supervision.


4. Side Effects

As with all chemotherapy medications, Halaven 1mg Injection may cause side effects. It is important to be monitored by a healthcare provider throughout treatment to manage any adverse effects.

Common Side Effects:

  • Fatigue or weakness

  • Nausea or vomiting

  • Hair loss (alopecia)

  • Constipation

  • Loss of appetite

  • Peripheral neuropathy (numbness or tingling in hands and feet)

  • Low white blood cell count (neutropenia), which can increase infection risk

Serious Side Effects:

  • Severe neutropenia leading to fever/infection

  • Heart rhythm abnormalities (QT prolongation)

  • Liver function disturbances

  • Difficulty breathing or allergic reactions (rare)

Monitoring:
Your doctor may recommend regular blood tests to check blood counts, electrolyte levels, liver function, and heart rhythm (ECG) before and during treatment.

Always inform your doctor of any unusual symptoms, especially fever, chest pain, or numbness, while on Halaven.


5. Frequently Asked Questions (FAQ)

Q1. What is Halaven 1mg Injection used for?
A: Halaven is primarily used to treat metastatic breast cancer and advanced liposarcoma in adults, particularly after other treatments have failed.

Q2. How is Halaven administered?
A: It is given as an intravenous (IV) infusion over 2 to 5 minutes, usually once a week on days 1 and 8 of a 21-day cycle under a healthcare provider’s supervision.

Q3. Can Halaven cure cancer?
A: Halaven is not a cure, but it can help slow the progression of the disease, reduce tumor size, and improve survival rates in patients with advanced cancer.

Q4. How long can I take Halaven?
A: The duration depends on how well your body tolerates the medication and how the cancer responds. Your doctor will assess your condition before each cycle.

Q5. What precautions should I take during treatment?
A: Avoid infections, maintain hygiene, eat healthy, and attend all scheduled check-ups. Notify your doctor immediately if you develop fever, weakness, or unusual bleeding.

Q6. Can pregnant or breastfeeding women take Halaven?
A: No. Halaven should not be used during pregnancy or breastfeeding as it can harm the baby. Effective contraception should be used during and for some time after treatment.

Q7. Will Halaven affect my fertility?
A: Like many chemotherapy agents, Halaven may affect fertility. Speak to your doctor about fertility preservation options before starting treatment.

Q8. Can I drive or operate machinery after taking Halaven?
A: It may cause fatigue or dizziness. Avoid driving or operating machinery until you know how the medication affects you.

Q9. Are there any drug interactions with Halaven?
A: Yes. Inform your doctor about all medicines you are taking, especially those affecting liver enzymes or heart rhythm, including herbal supplements.

Q10. What if I miss a dose?
A: Since Halaven is administered in a clinical setting, missed doses are uncommon. If a dose is missed, your oncologist will reschedule it accordingly.


References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 489.
  2. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
  3. Eribulin Mesylate. Frankfurt am Main Germany: Eisai GmbH; 17 Mar. 2011 [revised Jan. 2019]. [Accessed 27 Mar. 2019] (online) Available from:External Link
  4. Cancer Research Uk. Eribulin Mesylate. [Accessed 27 Mar. 2019] (online) Available from:External Link


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