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Intaxel 30mg Injection

Original price was: ₹1,154.00.Current price is: ₹480.00.

  Prescription Required

Salt : Paclitaxel

Manufacturer : FRESENIUS KABI INDIA PVT LTD

Packing : 5 ml in 1 vial

Description

1. Product Introduction

Intaxel 30mg Injection is a chemotherapy medication used in the treatment of various types of cancers. It contains the active substance Paclitaxel, which belongs to a class of drugs known as taxanes. Taxanes work by inhibiting the normal breakdown of microtubules during cell division, effectively stopping the growth and spread of cancer cells.

Manufactured with stringent quality controls, Intaxel 30mg is administered under the supervision of healthcare professionals in a clinical or hospital setting. It is given via intravenous infusion, and the dosage is determined based on the type of cancer, the patient’s weight, medical condition, and response to previous treatments.

This injection is a crucial component of combination chemotherapy regimens and is widely used due to its efficacy and ability to treat a wide range of malignancies.


2. Uses of Intaxel 30mg Injection

Intaxel 30mg Injection is used to treat various types of cancers, including:

  • Ovarian Cancer: Often used as first-line and subsequent therapy.

  • Breast Cancer: Particularly in cases that are resistant to anthracycline-based treatments.

  • Non-Small Cell Lung Cancer (NSCLC): Administered in combination with other agents like cisplatin.

  • Kaposi’s Sarcoma: Especially in patients with AIDS-related Kaposi’s sarcoma.

  • Pancreatic Cancer: Sometimes used in combination with other chemotherapy drugs.

  • Head and Neck Cancers: Occasionally part of multimodal cancer management.

It may be used as a monotherapy or in combination with other chemotherapeutic agents depending on the specific clinical requirement.


3. Benefits of Intaxel 30mg Injection

  • Broad-Spectrum Activity: Effective against a wide range of cancers, especially those that are difficult to treat with conventional therapies.

  • Prevents Cancer Cell Multiplication: Paclitaxel stabilizes microtubules, preventing cancer cells from dividing, which slows or stops tumor growth.

  • Enhances Survival Rates: When used as part of a combination therapy, it significantly improves survival outcomes in patients with advanced-stage cancers.

  • Reduces Recurrence Risk: Helps in reducing the risk of cancer recurrence, especially when used as adjuvant therapy.

  • Improves Quality of Life: Despite being a potent chemotherapeutic, many patients report better symptom control and an improved sense of well-being when the cancer burden is reduced.


4. Side Effects

Like all chemotherapy medications, Intaxel 30mg Injection may cause side effects. However, not all patients experience them, and many can be managed effectively.

Common Side Effects:

  • Nausea and Vomiting

  • Hair Loss (Alopecia)

  • Fatigue or Weakness

  • Decreased White Blood Cell Count (Neutropenia)

  • Peripheral Neuropathy (Tingling or Numbness in Hands and Feet)

  • Mouth Sores

  • Muscle or Joint Pain

Serious Side Effects (require immediate medical attention):

  • Severe Allergic Reactions (swelling, breathing difficulty, rash)

  • Heart Rhythm Problems

  • Liver Dysfunction (elevated liver enzymes)

  • Infections due to Low Immunity

  • Bleeding or Bruising Easily

Patients are usually pre-medicated with corticosteroids and antihistamines to reduce the risk of allergic reactions. Regular monitoring of blood counts and liver function is advised during treatment.


5. Frequently Asked Questions (FAQs)

Q1. How is Intaxel 30mg Injection administered?
A: Intaxel is administered through an intravenous (IV) infusion, typically over a period of 1 to 3 hours. It is given by a trained medical professional in a hospital or cancer care center.

Q2. How often will I need to receive this injection?
A: The dosing schedule depends on the type and stage of cancer, treatment goals, and patient response. It can be administered once every 1 to 3 weeks. Your oncologist will decide the most appropriate regimen.

Q3. Can I take Intaxel 30mg at home?
A: No, this medication must be administered in a controlled clinical setting under professional supervision due to the risk of severe allergic reactions and the need for monitoring.

Q4. Will I lose my hair during treatment with Intaxel?
A: Hair loss is a common side effect of Paclitaxel. Hair typically grows back after the treatment is completed, although the texture and color may change temporarily.

Q5. Is there anything I can do to reduce side effects?
A: Eating a healthy diet, staying hydrated, resting adequately, and promptly reporting any symptoms to your doctor can help manage side effects. Your doctor may prescribe medications to reduce nausea, manage pain, or prevent infections.


References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1707-709.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 949.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1044-46.
  4. Paclitaxel. Hurley, Maidenhead: Hospira UK Ltd.; 2005 [revised Dec. 2016]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  5. Paclitaxel. Summit, New Jersey: Celgene Corporation; 2005 [revised Oct. 2012]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  6. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Paclitaxel. [Updated 2020 Jan 20]. [Accessed 18 Feb. 2020] (online) Available from:External Link


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