

Lenangio 5mg Capsule
₹632.00 Original price was: ₹632.00.₹480.00Current price is: ₹480.00.
Prescription Required
Salt : Lenalidomide (5mg)
Manufacturer : Dr Reddy’s Laboratories Ltd
Packing : 10 capsules in 1 strip
1. Product Introduction
Lenangio 5mg Capsule is a prescription medicine that contains Lenalidomide (5mg) as its active ingredient. It belongs to a class of drugs known as immunomodulatory agents, and it is primarily used in the treatment of specific types of cancers and blood disorders. This medicine is structurally related to thalidomide but has improved safety and efficacy profiles.
Lenangio works by enhancing the immune system’s ability to fight cancer, inhibiting the growth of cancerous cells, and reducing the formation of blood vessels that tumors need to grow. It has both anti-inflammatory and anti-cancer properties, making it a critical part of many cancer treatment regimens.
This medicine is usually taken once a day in treatment cycles, which vary based on the type of cancer being treated. It must be taken exactly as prescribed by a healthcare provider. Due to its potential risks, especially in pregnancy, this drug is dispensed under strict safety guidelines.
2. Uses of Lenangio 5mg Capsule
Lenangio 5mg Capsule is used to treat several hematologic (blood-related) cancers and disorders. Its main uses include:
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Multiple Myeloma: A cancer of plasma cells in the bone marrow. Lenangio is usually used in combination with dexamethasone and/or other agents.
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Myelodysplastic Syndromes (MDS): A group of disorders caused by poorly formed or dysfunctional blood cells. Lenangio is especially effective in MDS patients with a specific chromosomal abnormality called deletion 5q.
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Mantle Cell Lymphoma (MCL): A rare and aggressive type of non-Hodgkin lymphoma. Lenangio is used when other treatments have failed or in relapsed cases.
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Follicular and Diffuse Large B-Cell Lymphomas: In certain cases, Lenangio is used off-label or in clinical settings as part of combination therapy.
3. Benefits of Lenangio 5mg Capsule
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Slows Cancer Progression: Lenangio helps delay the growth and spread of cancer cells, significantly improving survival rates in multiple myeloma and MDS patients.
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Stimulates Immune Response: It boosts the immune system to detect and destroy abnormal cells, acting as a targeted immune-based therapy.
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Oral Convenience: It is taken orally, which makes it less invasive compared to intravenous chemotherapy.
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Improves Quality of Life: Lenangio can reduce the need for blood transfusions in MDS patients and decrease bone pain and fatigue in multiple myeloma patients.
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Prolonged Remission: When used in maintenance therapy for multiple myeloma, it has been shown to extend the duration of remission and delay disease recurrence.
4. Side Effects of Lenangio 5mg Capsule
As with all anti-cancer medications, Lenangio 5mg Capsule can cause side effects. Some are common and manageable, while others may require medical attention.
Common Side Effects:
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Fatigue or tiredness
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Nausea or vomiting
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Diarrhea or constipation
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Skin rash or itching
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Dizziness or headache
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Back pain or muscle cramps
Serious Side Effects (Seek medical help):
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Low Blood Cell Counts: Can lead to anemia, infections, or bleeding. Regular blood tests are essential.
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Blood Clots: Increased risk of deep vein thrombosis (DVT) and pulmonary embolism. Preventive measures like blood thinners may be prescribed.
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Liver or Kidney Dysfunction: Monitoring of liver and kidney function is required during treatment.
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Birth Defects: Lenalidomide can cause severe birth defects if taken during pregnancy. Strict pregnancy prevention programs are followed.
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Severe Allergic Reactions: Including swelling of the face, lips, throat, or difficulty breathing.
Precautions:
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Do not take this medicine if you are pregnant or planning to become pregnant.
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Men taking Lenangio should also use contraception, as the drug can be present in semen.
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Do not donate blood or sperm during treatment and for a period after stopping it.
5. Frequently Asked Questions (FAQs)
Q1. What is Lenangio 5mg Capsule used for?
A1. Lenangio is used to treat multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, and other related blood cancers. It works by modifying the immune response and targeting cancer cells.
Q2. How should I take Lenangio 5mg Capsule?
A2. Take it exactly as prescribed by your doctor, usually once daily with or without food. Swallow the capsule whole with water, and do not crush or open it.
Q3. Can women take Lenangio during pregnancy?
A3. No. Lenangio is highly unsafe during pregnancy and can cause life-threatening birth defects. Women of childbearing age must use two forms of contraception and undergo regular pregnancy testing.
Q4. What happens if I miss a dose?
A4. If you miss a dose and less than 12 hours have passed, take it as soon as you remember. If more than 12 hours have passed, skip the missed dose and resume your regular schedule. Do not double up doses.
Q5. How long do I need to take Lenangio?
A5. The duration of treatment depends on your medical condition and your response to therapy. It may be taken in cycles for several months or as long-term maintenance in multiple myeloma.
References
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Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1742.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 784-85.
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Lenalidomide [Prescribing Information]. Nantou City, Taiwan: Lotus Pharmaceutical Co., Ltd.; 2022. [Accessed 08 Jul. 2023]. (online) Available from:
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