Lenshil 4mg Capsule

1. Product Introduction

Lenshil 4mg Capsule contains Lenvatinib, a powerful anti-cancer medication used in the treatment of various types of cancers. It belongs to a class of medicines called tyrosine kinase inhibitors (TKIs), which work by blocking the activity of specific enzymes responsible for the growth and spread of cancer cells.

Lenvatinib is a targeted therapy, which means it specifically attacks cancer cells while minimizing harm to healthy cells. Lenshil 4mg is manufactured in a capsule form for oral administration and is typically prescribed either alone or in combination with other cancer therapies depending on the type and stage of cancer.

This medicine is prescribed under strict medical supervision and requires routine monitoring during the treatment course. It plays a crucial role in managing advanced and difficult-to-treat cancers where other therapies may not be effective.

2. Uses of This Medicine

Lenshil 4mg Capsule (Lenvatinib 4mg) is primarily used in the treatment of various advanced-stage or metastatic cancers, especially when the disease is not amenable to surgical removal or has recurred. Its main indications include:

• Thyroid Cancer: Specifically, for differentiated thyroid cancer (DTC) that is radioactive iodine-refractory.

• Liver Cancer (Hepatocellular Carcinoma): As a first-line treatment in patients who are not eligible for surgical or locoregional therapies.

• Kidney Cancer (Renal Cell Carcinoma): Often used in combination with everolimus or pembrolizumab for advanced renal cell carcinoma.

• Endometrial Cancer: In combination with pembrolizumab for patients with advanced or recurrent disease.

Your oncologist will determine the correct dosage and whether Lenshil 4mg is to be used alone or alongside other treatments depending on your specific diagnosis and overall health status.

3. Benefits of This Medicine

Lenshil 4mg Capsule provides significant therapeutic advantages in the management of complex cancers. Some of its key benefits include:

• Targeted Action: Lenvatinib targets multiple pathways (VEGFR, FGFR, PDGFR, RET, and KIT), which are crucial for tumor growth and angiogenesis (formation of new blood vessels that supply the tumor).

• Effective in Resistant Cases: Especially beneficial in patients whose cancers are resistant to conventional therapies such as chemotherapy or radioactive iodine.

• Delays Disease Progression: Clinical trials have shown that Lenvatinib can significantly delay tumor growth, improve progression-free survival, and enhance quality of life in patients with advanced cancers.

• Convenient Oral Dosage Form: Being available as an oral capsule allows patients to take the treatment at home under medical guidance, reducing hospital visits.

• Combination Therapy Potential: Shows enhanced anti-tumor activity when combined with other agents like immune checkpoint inhibitors (e.g., pembrolizumab).

Due to its targeted nature, Lenshil 4mg often provides better outcomes compared to traditional chemotherapy, especially when used in the correct patient population.

4. Side Effects

As with most cancer treatments, Lenshil 4mg Capsule may cause certain side effects. Most side effects are manageable and reduce with supportive care or dose adjustment.

Common Side Effects:

• Fatigue or weakness

• High blood pressure (hypertension)

• Diarrhea

• Loss of appetite

• Weight loss

• Nausea and vomiting

• Mouth sores

• Muscle or joint pain

• Hand-foot syndrome (redness or pain in hands/feet)

Serious Side Effects (Rare but Require Immediate Attention):

• Liver problems (yellowing of eyes/skin, dark urine)

• Kidney dysfunction

• Protein in urine

• Blood clots or bleeding

• Heart rhythm abnormalities

• Severe headache or confusion (signs of brain swelling or bleeding)

Monitoring:
Regular monitoring of blood pressure, liver function tests, kidney function, and ECG may be required during treatment. Inform your doctor of any persistent or severe symptoms.

5. Frequently Asked Questions (FAQ)

Q1. What is Lenshil 4mg Capsule used for?
A: Lenshil 4mg is used to treat several types of advanced or metastatic cancers, such as thyroid, liver, kidney, and endometrial cancers, especially when the cancer is not responding to other treatments.

Q2. How should I take this medicine?
A: Take Lenshil 4mg exactly as prescribed by your doctor. It should be swallowed whole with water, preferably at the same time each day, with or without food.

Q3. Can I stop taking Lenshil if I feel better?
A: No. Even if you feel better, do not stop the medicine without consulting your oncologist. Stopping it suddenly can affect treatment outcomes.

Q4. What precautions should I take while on this medicine?
A: Monitor your blood pressure regularly, stay well-hydrated, avoid grapefruit or grapefruit juice (may increase side effects), and inform your doctor about any other medications or supplements you are taking.

Q5. Is it safe to take Lenshil 4mg during pregnancy or breastfeeding?
A: No, this medicine can harm an unborn baby. It should not be taken during pregnancy or while breastfeeding. Women of childbearing potential should use effective contraception during treatment and for at least one month after stopping.