Enoxarin 40mg Injection
Enoxarin 40mg Injection Original price was: ₹474.00.Current price is: ₹270.00.
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LMWX 40 Injection
LMWX 40 Injection Original price was: ₹470.27.Current price is: ₹180.00.

Lonopin 40mg Injection

Original price was: ₹470.27.Current price is: ₹250.00.

  Prescription Required

Salt : Enoxaparin

Manufacturer : Bharat Serums And Vaccines Ltd.

Packing : 1 Prefilled Syringe(S) Of 0.4ml

Description

1. Product Introduction

Lonopin 40mg Injection is a prescription anticoagulant medicine that contains Enoxaparin, a low molecular weight heparin (LMWH). It is primarily used to prevent and treat blood clots, particularly in patients undergoing surgeries or those at high risk of clot-related complications. Enoxaparin works by inhibiting certain clotting factors in the blood, especially Factor Xa, thereby reducing the risk of clot formation.

This injection is typically administered subcutaneously (under the skin) in the hospital or can be prescribed for home use under medical guidance. It is well-recognized for its predictable action, ease of dosing, and lower risk of severe side effects compared to traditional anticoagulants like unfractionated heparin.

Lonopin 40mg is widely used across surgical, cardiac, and critical care settings.


2. Uses of This Medicine

Lonopin 40mg Injection is used for the treatment and prevention of various thromboembolic disorders, including:

  • Prevention of Deep Vein Thrombosis (DVT):
    After orthopedic (hip/knee) or abdominal surgeries, when patients are immobile and at high risk of clot formation.

  • Treatment of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE):
    It helps in dissolving existing clots and prevents their migration to vital organs like the lungs.

  • Prevention of Thromboembolic Complications in Immobilized Patients:
    Especially useful in patients who are on prolonged bed rest due to illness or hospitalization.

  • Management of Unstable Angina and Non-ST Elevation Myocardial Infarction (NSTEMI):
    Helps reduce the risk of clot formation in heart arteries, lowering chances of a heart attack.

  • Prevention of Clot Formation in Hemodialysis Circuits:
    Ensures smooth blood flow during dialysis procedures.


3. Benefits of This Medicine

Lonopin 40mg Injection offers multiple clinical and practical benefits:

  • Highly Effective Anticoagulant:
    Proven efficacy in preventing and treating blood clots.

  • Rapid Onset of Action:
    Starts working within hours, making it suitable for emergency and acute care.

  • Lower Risk of Bleeding Compared to Heparin:
    Offers more targeted action with a reduced risk of heparin-induced thrombocytopenia (HIT).

  • No Routine Monitoring Required:
    Unlike warfarin or traditional heparin, Enoxaparin generally does not require frequent blood tests to monitor clotting levels.

  • Safe for Use in Pregnancy:
    Preferred anticoagulant for pregnant women with clotting disorders or thrombophilia.

  • Convenient Dosing:
    Fixed-dose injections based on body weight, easy to administer at home if needed.

  • Improved Recovery Post-Surgery:
    Reduces complications such as pulmonary embolism and DVT after major surgeries.


4. Side Effects

Like all medications, Lonopin 40mg Injection may cause side effects. Most are mild and temporary, but some may require medical attention.

Common Side Effects:

  • Pain, redness, or bruising at the injection site

  • Minor bleeding (nosebleeds, bleeding gums, easy bruising)

  • Headache

  • Nausea or vomiting

  • Mild swelling or irritation at the site of injection

Serious Side Effects (Seek Immediate Medical Help):

  • Excessive or prolonged bleeding

  • Blood in urine or stool

  • Low platelet count (thrombocytopenia)

  • Severe headache or vision changes (possible internal bleeding)

  • Spinal hematoma (especially if spinal anesthesia or puncture is used)

  • Allergic reactions – rash, itching, difficulty breathing, swelling

Precautions:

  • Patients with kidney disease, bleeding disorders, or history of ulcers should use this with caution.

  • Avoid concurrent use with other blood thinners unless prescribed.

  • Regular follow-up is recommended for long-term users or those with additional risk factors.


5. Frequently Asked Questions (FAQ)

Q1. How is Lonopin 40mg Injection administered?
A: It is given as a subcutaneous injection, usually in the abdominal area. It can be administered by a healthcare provider or self-injected after proper training.

Q2. Can I self-inject Lonopin at home?
A: Yes, your doctor or nurse can teach you how to self-administer it. Follow the dosage and technique strictly as prescribed.

Q3. What should I do if I miss a dose?
A: If you miss a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed one—never double the dose. Inform your doctor if multiple doses are missed.

Q4. Is Lonopin safe during pregnancy?
A: Yes, Enoxaparin is considered safe during pregnancy and is often used to treat or prevent clots in pregnant women. However, use only under the guidance of your obstetrician.

Q5. What are the signs of overdose or serious side effects?
A: Signs include unusual bleeding, black or bloody stools, severe headaches, or dizziness. In such cases, seek emergency medical attention.


References

  1. Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 373-74.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 471.
  3. Enoxaparin sodium. Guildford, Surrey: SANOFI; 1997 [revised 08 Apr. 2018]. [Accessed 18 Mar. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Enoxaparin. [Updated 2020 Jan 20]. [Accessed 19 Feb. 2020] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). Enoxaparin. [Accessed 18 Mar. 2019] (online) Available from:External Link
  6. Enoxaparin [Dosage and Administration Guide]. [Accessed 20 June 2023]. (online) Available from:External Link
  7. Enoxaparin [Prescribing Information]. Rancho Cucamonga, CA: Amphastar Pharmaceuticals, Inc.; 2023. [Accessed 20 June 2023]. (online) Available from:External Link


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