Mabtas 500mg Injection

Product Introduction

Mabtas 500mg Injection contains Rituximab (500mg), a monoclonal antibody used to treat various types of blood cancers and autoimmune diseases. It works by targeting and destroying specific cells in the immune system, making it an effective therapy for conditions like non-Hodgkin’s lymphoma (NHL), chronic lymphocytic leukemia (CLL), and rheumatoid arthritis.

This medication is administered as an intravenous (IV) infusion under the supervision of a qualified healthcare professional. Mabtas 500mg is known for its precision in targeting abnormal B-cells while minimizing damage to healthy tissues. The treatment is often used in combination with other chemotherapy drugs to enhance its effectiveness.

Due to the complexity of Rituximab therapy, it is crucial for patients to undergo pre-treatment screening and continuous monitoring to prevent severe reactions. Doctors may prescribe pre-medications, such as antihistamines and corticosteroids, to minimize infusion-related side effects.

Uses of Mabtas 500mg Injection

• Non-Hodgkin’s Lymphoma (NHL): Used as a primary or adjunct therapy to destroy cancerous B-cells in lymphomas.

• Chronic Lymphocytic Leukemia (CLL): Helps control abnormal growth of white blood cells in leukemia.

• Rheumatoid Arthritis (RA): Suppresses overactive immune responses to reduce joint inflammation and pain.

• Granulomatosis with Polyangiitis & Microscopic Polyangiitis: Helps control inflammation in these autoimmune disorders.

• Pemphigus Vulgaris: Used in severe cases to manage this rare skin condition by suppressing autoimmune activity.

Benefits of Mabtas 500mg Injection

1. Effective Targeted Therapy:

   • Specifically targets CD20-positive B cells, making it a precise treatment for lymphoma and leukemia.

2. Slows Disease Progression:

   • Helps delay the advancement of cancer and autoimmune diseases, improving survival rates and quality of life.

3. Enhances Chemotherapy Effectiveness:

   • Often combined with chemotherapy to improve the overall treatment response and reduce relapse rates.

4. Reduces Joint Damage in Rheumatoid Arthritis:

   • Helps lower joint inflammation, pain, and stiffness in RA patients who do not respond to standard treatments.

5. Long-Lasting Effects:

   • Provides prolonged remission in cancer patients, reducing the need for frequent treatments.

6. Minimal Impact on Healthy Cells:

   • Unlike conventional chemotherapy, Rituximab primarily affects B-cells, leaving other immune cells mostly intact.

7. Improves Symptoms in Autoimmune Disorders:

   • Helps regulate immune overactivity, providing relief from severe inflammation and organ damage.

Side Effects of Mabtas 500mg Injection

While Mabtas 500mg is effective, it can cause certain side effects, ranging from mild to severe. Patients are advised to undergo medical supervision during and after infusion.

Common Side Effects:

• Fever and chills

• Nausea or vomiting

• Headache

• Fatigue

• Weakness

• Skin rash or itching

• Muscle pain

Serious Side Effects (Require Immediate Medical Attention):

• Infusion-related reactions – Shortness of breath, dizziness, rapid heartbeat, or low blood pressure during or after infusion

• Increased risk of infections – As Rituximab suppresses immune function, it may increase the likelihood of bacterial, viral, or fungal infections

• Severe allergic reactions – Swelling of face, lips, or throat, leading to breathing difficulties

• Hepatitis B reactivation – Patients with a history of hepatitis B virus (HBV) must be monitored closely

• Progressive Multifocal Leukoencephalopathy (PML) – A rare but serious brain infection caused by the JC virus, leading to neurological symptoms like vision problems and difficulty speaking

Important Precaution:
Before starting Mabtas 500mg, your doctor may conduct tests to check for infections and liver health to prevent complications.

Frequently Asked Questions (FAQ)

1. How does Mabtas 500mg work?

Mabtas 500mg (Rituximab) is a monoclonal antibody that binds to CD20 proteins on B-cells, marking them for destruction. This helps treat cancers like NHL and CLL, as well as autoimmune diseases like RA and Pemphigus Vulgaris.

2. How is Mabtas 500mg Injection administered?

This injection is given intravenously (IV) in a hospital setting. The infusion process can take several hours, and patients are closely monitored for any reactions.

3. How long does Mabtas 500mg take to show results?

The response time varies based on the disease being treated.

• For cancer patients, improvement is usually observed after a few treatment cycles.

• In RA and autoimmune disorders, symptom relief can take several weeks.

4. Can I take Mabtas 500mg if I have an infection?

No, Rituximab weakens the immune system, making infections worse. Inform your doctor if you have any ongoing or recent infections before starting treatment.

5. What should I do if I miss a dose?

Since Mabtas 500mg is given in a hospital under a doctor’s supervision, missing a dose is rare. However, if a session is delayed, consult your doctor for rescheduling the infusion.