Mytera 250mg Tablet

1. Product Introduction

Mytera 250mg Tablet is a prescription medication that contains Abiraterone Acetate as its active ingredient. It belongs to a class of drugs known as androgen biosynthesis inhibitors, which are primarily used in the treatment of prostate cancer. This medicine is especially used in combination with corticosteroids like prednisone or prednisolone to treat metastatic castration-resistant prostate cancer (mCRPC) and metastatic high-risk castration-sensitive prostate cancer (mCSPC).

Prostate cancer cells need androgens like testosterone to grow. Mytera works by inhibiting an enzyme called CYP17, which is involved in the production of testosterone. By reducing testosterone levels in the body, the growth of cancer cells can be slowed down or even stopped.

This medication is available in tablet form and is usually taken orally once daily, on an empty stomach, as food can increase the absorption and risk of side effects. The dosage and duration are determined by the healthcare provider based on the patient’s condition and response to treatment.

2. Uses of Mytera 250mg Tablet

Mytera 250mg Tablet is used in the treatment of:

• Metastatic Castration-Resistant Prostate Cancer (mCRPC): This is an advanced form of prostate cancer that continues to grow even when the testosterone levels are reduced to very low levels through surgery or medication.

• Metastatic High-Risk Castration-Sensitive Prostate Cancer (mCSPC): This refers to prostate cancer that has spread to other parts of the body and still responds to testosterone-lowering treatments.

Mytera is always used in combination with corticosteroids and often alongside other medications as part of a complete cancer treatment plan.

3. Benefits of Mytera 250mg Tablet

• Slows Cancer Progression: Mytera helps reduce testosterone levels, thereby limiting the fuel that prostate cancer cells need to grow and spread.

• Improved Survival Rates: Clinical studies have shown that Abiraterone Acetate improves overall survival and delays the progression of cancer in patients with advanced prostate cancer.

• Delays the Need for Chemotherapy: For many patients, Mytera helps in postponing the use of chemotherapy, thereby reducing exposure to harsh side effects.

• Better Quality of Life: By controlling the progression of prostate cancer, Mytera helps reduce symptoms like bone pain, fatigue, and urinary problems, offering a better quality of life.

• Oral Administration: The tablet form allows for convenient daily dosing at home, without the need for injections or hospital visits.

4. Side Effects

Like all medicines, Mytera 250mg Tablet may cause some side effects. However, not everyone experiences them. Some common and serious side effects include:

Common Side Effects:

• High blood pressure

• Low potassium levels

• Fluid retention and swelling (especially in feet or ankles)

• Fatigue and weakness

• Increased liver enzymes

• Joint pain or muscle discomfort

• Hot flashes

Serious Side Effects:

• Liver problems (symptoms include dark urine, yellowing of skin or eyes, severe fatigue)

• Adrenal gland problems

• Irregular heartbeats

• Shortness of breath or chest discomfort

If any of these side effects persist or worsen, it is important to contact your doctor immediately. Your healthcare provider may adjust your dosage or add additional medicines to manage these side effects.

5. Frequently Asked Questions (FAQs)

Q1. How should I take Mytera 250mg Tablet?
Take it on an empty stomach, at least 1 hour before or 2 hours after meals. Swallow the tablet whole with water. Do not crush or chew.

Q2. Can I take Mytera with food?
No, taking Mytera with food can increase the absorption of the drug, which may lead to more severe side effects. Always take it on an empty stomach.

Q3. Do I need to take any other medicine with Mytera?
Yes. Mytera is usually given with a corticosteroid like prednisone to help manage side effects such as increased blood pressure and fluid retention.

Q4. How long will I need to take this medicine?
Your doctor will determine the duration of treatment. It may continue for several months or even longer, depending on your response and tolerance.

Q5. What precautions should I take while on Mytera?

• Monitor blood pressure and liver function regularly.

• Avoid grapefruit or grapefruit juice, as it can interfere with the drug’s effectiveness.

• Inform your doctor if you are taking any other medicines or have a history of heart, liver, or adrenal disorders.

  ---

  References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
  2. Abiraterone acetate. High Wycombe, Buckinghamshire: Janssen-Cilag Ltd.; 2017. [Accessed 26 Mar. 2019] (online) Available from:
  3. Abiraterone Acetate. Patheon Inc.: Mississauga, Canada; 2011 [revised May 2016]. [Accessed 26 Mar. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
  5. Abiraterone acetate [Prescribing Information]. Toronto, Canada: Patheon Inc.; 2011. [Accessed 20 Feb. 2024] (online) Available from: 
  6. CiplaMed. Abiraterone Acetate [Prescribing Information]. [Accessed 25 Jul. 2024] (online) Available from:

     ---

     Disclaimer

     Online Medicos primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on  Online Medicos Our mission is to support, not replace, the doctor-patient relationship.