PACLIDIAN 100 Injection

1. Product Introduction

PACLIDIAN 100 Injection is a chemotherapy medication that contains Paclitaxel, a widely used anti-cancer agent belonging to the class of drugs known as taxanes. Derived from the bark of the Pacific yew tree, Paclitaxel has become a cornerstone in modern oncology for its ability to combat a variety of cancers.

PACLIDIAN works by inhibiting the division of cancer cells. It disrupts the microtubule structures within the cells, which are essential for cell division, thereby stopping the growth and spread of cancer.

This injection is administered intravenously by a healthcare professional in a hospital or clinical setting. It is used as monotherapy or in combination with other chemotherapy agents depending on the type and stage of cancer.

2. Uses of This Medicine

PACLIDIAN 100 Injection is prescribed for the treatment of multiple cancers, including:

• Breast Cancer: Used both in early-stage and metastatic cases.

• Ovarian Cancer: Effective in recurrent or advanced ovarian carcinoma.

• Non-Small Cell Lung Cancer (NSCLC): Often used with platinum-based chemotherapy.

• Pancreatic Cancer: Combined with gemcitabine for advanced or metastatic disease.

• AIDS-Related Kaposi’s Sarcoma: For patients who have not responded to other therapies.

The use of Paclitaxel depends on the individual cancer diagnosis, patient’s response to previous treatments, and other health conditions.

3. Benefits of This Medicine

The key benefits of PACLIDIAN 100 Injection include:

• Effective Cell Cycle Arrest: It disrupts cancer cell replication by stabilizing microtubules, stopping cell division.

• Broad Spectrum Activity: It is active against a wide variety of solid tumors.

• Tumor Shrinkage: Helps reduce tumor size, relieve pressure symptoms, and improve the patient’s quality of life.

• Combination Potential: Works effectively in combination with other drugs, enhancing the overall response rate.

• Proven Survival Benefit: In many cancers, especially breast and ovarian, it has significantly improved patient survival when used appropriately.

This medicine is highly valued in oncology for its versatility and robust therapeutic outcomes across multiple cancer types.

4. Side Effects

While PACLIDIAN 100 Injection is effective, it may cause some side effects. These can vary in intensity based on the dose, duration of treatment, and patient tolerance.

Common Side Effects:

• Hair loss (temporary)

• Nausea and vomiting

• Diarrhea or constipation

• Fatigue or weakness

• Loss of appetite

• Low blood counts (anemia, leukopenia, thrombocytopenia)

Serious Side Effects:

• Peripheral Neuropathy: Numbness, tingling, or pain in hands and feet.

• Severe Allergic Reactions: Chills, fever, breathing difficulty, rash. Premedication is often given to prevent this.

• Heart Issues: Irregular heartbeat or low blood pressure during infusion.

• Liver Enzyme Changes: May need liver function tests during treatment.

• Increased Risk of Infection: Due to suppressed immunity from low white blood cell counts.

Regular monitoring and supportive care can help manage these side effects. Always report any unusual symptoms to your doctor promptly.

5. Frequently Asked Questions (FAQ)

Q1. What is PACLIDIAN 100 Injection used for?
A: It is used to treat various types of cancer including breast, ovarian, lung, and pancreatic cancer, as well as AIDS-related Kaposi’s sarcoma.

Q2. How is PACLIDIAN 100 Injection administered?
A: It is given intravenously by a doctor or nurse, usually over 1–3 hours. Pre-medications may be given to prevent allergic reactions.

Q3. Can I take PACLIDIAN at home?
A: No, this injection must be administered in a clinical setting under the supervision of medical professionals due to potential side effects and the need for monitoring.

Q4. Will I lose my hair with PACLIDIAN 100 Injection?
A: Yes, temporary hair loss is a common side effect. However, your hair typically grows back once the treatment is completed.

Q5. What precautions should I take while on this treatment?
A: Avoid contact with sick individuals, maintain good hygiene, and follow your doctor’s advice on nutrition and hydration. Report any fever, sore throat, or unusual bleeding immediately.