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Renodapt 500mg Tablet

Original price was: ₹691.00.Current price is: ₹450.00.

  Prescription Required

Salt : Mycophenolate mofetil (500mg)

Manufacturer : Eris Lifesciences Ltd

Packing : 10 tablets in 1 strip

Description

1. Product Introduction

Renodapt 500mg Tablet contains the active ingredient Mycophenolate Mofetil (500mg), which is an immunosuppressant medication. It is commonly prescribed to patients who have undergone organ transplantation (such as kidney, heart, or liver transplants) to prevent the body from rejecting the transplanted organ. It works by weakening the immune system slightly so that it does not attack the newly transplanted organ.

Mycophenolate Mofetil is a prodrug, which means it becomes active once inside the body. It is converted into mycophenolic acid, which inhibits an enzyme crucial for the growth of T and B lymphocytes — cells that are part of the immune response. This targeted mechanism makes Renodapt an effective option in preventing graft rejection.

Renodapt 500mg Tablet is typically used along with other immunosuppressants like corticosteroids or calcineurin inhibitors (such as tacrolimus or cyclosporine) to provide a comprehensive approach to preventing organ rejection. It is taken orally under medical supervision and requires regular monitoring for potential side effects.


2. Uses of This Medicine

Renodapt 500mg Tablet is primarily used for:

  • Prevention of Organ Rejection:
    After organ transplantation (especially kidney, liver, or heart), the immune system may treat the new organ as a foreign object and try to reject it. Renodapt helps suppress this immune response.

  • Kidney Transplantation Support:
    Frequently used as part of a triple-drug regimen (with steroids and calcineurin inhibitors) in kidney transplant patients to reduce the risk of rejection.

  • Liver and Heart Transplant Rejection Prevention:
    Sometimes prescribed off-label or as an alternative to azathioprine in liver and heart transplant cases.

  • Autoimmune Diseases (off-label uses):
    In some cases, Mycophenolate Mofetil may be prescribed for conditions like lupus nephritis, rheumatoid arthritis, or autoimmune hepatitis under specialist supervision.


3. Benefits of This Medicine

  • Effective Rejection Prevention:
    Renodapt significantly reduces the risk of acute and chronic rejection episodes in organ transplant recipients.

  • Selective Immune Suppression:
    Targets only specific components of the immune system (T and B lymphocytes), reducing the likelihood of generalized immune suppression and associated infections.

  • Improves Graft Survival:
    Enhances the long-term success rate of kidney and other organ transplants.

  • Well-Tolerated Alternative:
    Provides an effective alternative to older immunosuppressants like azathioprine, with a more favorable side-effect profile in many patients.

  • Oral Convenience:
    Renodapt comes in tablet form, making it easier for patients to adhere to long-term immunosuppressive therapy.

For optimal results, Renodapt must be used exactly as prescribed and in conjunction with other medications as part of a full immunosuppressive regimen.


4. Side Effects

Like all medicines, Renodapt 500mg Tablet may cause side effects. While not everyone experiences them, being aware of potential adverse effects helps ensure early management.

Common Side Effects:

  • Nausea or vomiting

  • Diarrhea

  • Headache

  • High blood pressure

  • Anemia (low red blood cell count)

  • Increased susceptibility to infections

Serious Side Effects (seek medical help immediately):

  • Signs of infection (fever, chills, sore throat)

  • Signs of bleeding (easy bruising, unusual bleeding)

  • Abdominal pain with bloody stools

  • Trouble breathing or chest tightness

  • Skin rashes or blisters (especially if extensive)

Long-term Use Risks:

  • Increased risk of cancers, particularly skin cancer and lymphomas, due to long-term immune suppression.

  • Possible impact on fertility and fetal development (not safe in pregnancy).

Routine blood tests are necessary during treatment to monitor kidney function, white blood cell counts, and liver enzymes.


5. Frequently Asked Questions (FAQ)

Q1. What is Renodapt 500mg Tablet used for?
A: It is used to prevent rejection in organ transplant recipients, mainly kidney, heart, and liver transplants, by suppressing the body’s immune response.

Q2. How should I take Renodapt 500mg?
A: Take it exactly as prescribed by your doctor, usually twice daily. It should be taken on an empty stomach (1 hour before or 2 hours after meals), with a full glass of water.

Q3. Can I stop taking Renodapt once I feel fine?
A: No. Renodapt is a maintenance medication that prevents organ rejection. Stopping it without medical advice can lead to serious complications and organ failure.

Q4. Can Renodapt be taken during pregnancy?
A: No. Renodapt can cause birth defects or miscarriage. Women of childbearing potential must use effective contraception during treatment and for six weeks after stopping it.

Q5. What should I do if I miss a dose?
A: If you miss a dose, take it as soon as you remember. If it’s almost time for the next dose, skip the missed one. Do not double the dose.


References

  1. Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1014-15.
  2. Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 973.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 943-45.
  4. Mycophenolate mofetil. South San Francisco, California: Genentech USA, Inc.; 1995 [revised Feb. 2019]. [Accessed 17 Jun. 2019] (online) Available from:External Link
  5. Mycophenolate mofetil. Grenzach-Wyhlen, Germany: Roche Pharma AG; 2018. [Accessed 17 Jun. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation. Mycophenolate mofetil. [Accessed 25 Jul. 2023] (online) Available from:External Link
  7. Ensley RD, Bristow MR, Olsen SL, et al. The use of mycophenolate mofetil (RS-61443) in human heart transplant recipients. Transplantation. 1993 Jul;56(1):75-82. [Accessed 01 Aug. 2023] (online) Available from:External Link
  8. Mycophenolate mofetil. Basel, Switzerland: F. Hoffmann-La Roche Ltd.; 2021. [Accessed 25 Jul. 2023] (online) Available from:External Link
  9. Cell Cept. Mycophenolate mofetil. [Accessed 25 Jul. 2023] (online) Available from:External Link
  10. Mycophenolate mofetil [Prescribing Information]. Ahmedabad, India: Intas Pharmaceuticals Limited; 2023. [Accessed 25 Jul. 2023] (online) Available from:External Link


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We ship across India. Note – this is subject to change as per Company Wishes. Packages will be shipped in 24 working hours. we are closed on Sundays and will reach you in the next 2-4 days post shipping. We give the estimated time of delivery on the shipping page. However, these are indicative and depend on our shipping partner.

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