Resof Total 400mg/100mg Tablet

1. Product Introduction

Resof Total 400mg/100mg Tablet is a prescription medicine that combines two potent antiviral agents—Sofosbuvir (400mg) and Velpatasvir (100mg). This fixed-dose combination belongs to a class of drugs known as direct-acting antivirals (DAAs), specifically designed to treat chronic hepatitis C virus (HCV) infection in adults.

Hepatitis C is a viral infection that affects the liver, often leading to severe complications like liver cirrhosis, liver failure, or liver cancer if left untreated. Resof Total is highly effective in managing all six major genotypes of HCV, making it a pan-genotypic therapy. This oral tablet works by stopping the virus from multiplying and spreading in the body, leading to sustained virologic response (SVR), which is considered a functional cure in most patients.

The tablet is usually taken once daily for 12 weeks, with or without food, depending on the doctor’s instructions. This therapy has revolutionized the treatment of HCV, offering high cure rates, shorter treatment durations, and fewer side effects compared to traditional treatments.

2. Uses of Resof Total 400mg/100mg Tablet

Resof Total is primarily used for the treatment of:

• Chronic Hepatitis C Virus (HCV) infection in adults

• Effective against all major genotypes (1-6) of HCV

• Used in patients with or without cirrhosis (compensated or decompensated)

• May be prescribed in combination with Ribavirin for patients with more advanced liver disease

Note: The use and duration of therapy may vary based on the genotype, liver condition, and treatment history of the patient.

3. Benefits of Resof Total 400mg/100mg Tablet

• ✅ Pan-Genotypic Therapy: Effective for treating all genotypes of Hepatitis C virus, simplifying treatment decisions.

• ✅ High Cure Rate: Clinical studies show SVR (Sustained Virologic Response) rates of over 95% in most patients, which means the virus becomes undetectable after completion of therapy.

• ✅ Once-Daily Oral Dosage: Easy to administer, improving patient compliance.

• ✅ Short Treatment Duration: Most patients complete the course within 12 weeks.

• ✅ Minimal Side Effects: Generally well-tolerated compared to older interferon-based treatments.

• ✅ Improves Liver Health: Stops further liver damage and improves liver enzyme levels.

• ✅ Reduces Risk of Liver Complications: Lowers chances of liver cirrhosis, hepatocellular carcinoma, and liver failure.

4. Side Effects

Resof Total is generally safe and well-tolerated. However, like all medicines, it may cause some side effects in a few individuals. Common side effects include:

Common Side Effects:

• Fatigue

• Headache

• Nausea

• Insomnia (trouble sleeping)

• Diarrhea

• Irritability

Less Common but Serious Side Effects:

• Anemia (especially if taken with Ribavirin)

• Liver function abnormalities

• Allergic reactions (rash, itching, swelling)

• Depression or mood changes

Seek immediate medical attention if you experience signs of a severe allergic reaction such as difficulty breathing, swelling of the face or throat, or severe dizziness.

Note: Patients with co-infections (e.g., Hepatitis B or HIV) or liver/kidney problems should consult their doctor for tailored advice.

5. Frequently Asked Questions (FAQs)

Q1. How does Resof Total work?
A: Resof Total contains two antiviral agents—Sofosbuvir and Velpatasvir—that inhibit different proteins essential for the replication of the Hepatitis C virus. Together, they stop the virus from multiplying, ultimately clearing it from the body.

Q2. Can Resof Total cure Hepatitis C?
A: Yes, in most cases. When taken correctly for the full duration, Resof Total can achieve a sustained virologic response (SVR), meaning the virus becomes undetectable and stays that way even after treatment ends. This is considered a functional cure.

Q3. How long do I need to take this medicine?
A: The usual course is 12 weeks, but this may vary depending on your specific condition, liver function, and co-infections. Always follow your doctor’s prescribed duration.

Q4. Can Resof Total be used with other medications?
A: It may be used with other antiviral agents like Ribavirin in certain cases. However, it’s essential to inform your doctor about all other medications or supplements you’re taking to avoid harmful drug interactions.

Q5. Are there any food restrictions while using Resof Total?
A: No significant food restrictions. The tablet can be taken with or without food, but it’s best to take it at the same time daily for consistency.