Revolade 25mg Tablet

1. Product Introduction

Revolade 25mg Tablet contains the active ingredient Eltrombopag, a medication primarily used to increase platelet counts in certain blood disorders. It belongs to a class of drugs known as thrombopoietin receptor agonists, which stimulate the production of platelets by acting on the bone marrow.

Eltrombopag is a breakthrough treatment option for patients suffering from chronic immune thrombocytopenia (ITP) and other platelet deficiency conditions. It is especially beneficial when other treatments such as corticosteroids or immunoglobulins have not worked well.

Revolade is administered orally and is carefully dosed depending on the patient’s platelet count and response to therapy. It is a long-term therapy in some patients and requires periodic monitoring of liver function and blood counts.

2. Uses of This Medicine

Revolade 25mg Tablet is prescribed for the following medical conditions:

• Chronic Immune Thrombocytopenia (ITP):
  Used in adults and children over 1 year with ITP who have not responded adequately to other treatments like steroids or splenectomy.

• Hepatitis C-Associated Thrombocytopenia:
  To increase platelet counts in patients with chronic hepatitis C to initiate or maintain interferon-based therapy.

• Severe Aplastic Anemia (SAA):
  In patients with SAA who have not responded to immunosuppressive therapy, or in combination with other medications to stimulate bone marrow.

Revolade is not intended for use in normal thrombocytopenia cases caused by chemotherapy or other medications unless prescribed by a specialist.

3. Benefits of This Medicine

✅ Boosts Platelet Production:
Eltrombopag directly stimulates the bone marrow to produce more platelets, reducing the risk of bleeding in patients with low platelet counts.

✅ Alternative to Invasive Treatments:
Revolade offers a non-invasive alternative for patients who are unresponsive to splenectomy or steroids, eliminating the need for surgical interventions.

✅ Improves Treatment Compliance in Hepatitis C:
By increasing platelets, Revolade helps patients maintain interferon-based therapy without dose interruptions or discontinuation due to low platelet counts.

✅ Oral Administration for Convenience:
Unlike some therapies that require injections or infusions, Revolade is taken as an oral tablet, improving ease of use and adherence.

✅ Reduces Bleeding Episodes:
Patients experience fewer bleeding episodes, bruising, and petechiae, which significantly enhances quality of life.

✅ Supports Bone Marrow Recovery in Aplastic Anemia:
In combination with other agents, Revolade can stimulate bone marrow activity in patients with severely suppressed marrow.

4. Side Effects

Although Revolade 25mg Tablet is generally well tolerated, it may cause side effects in some patients. Most side effects are manageable and temporary, especially when the medication is taken under proper medical supervision.

Common Side Effects:

• Nausea or vomiting

• Headache

• Fatigue

• Muscle or joint pain

• Diarrhea

• Upper respiratory tract infection

Serious Side Effects:

• Liver enzyme elevation or liver damage

• Cataract formation (with long-term use)

• Thrombosis (blood clots) in some patients with excessively high platelet counts

• Bone marrow fibrosis (rare)

• Increased risk of leukemia progression (in certain conditions like MDS)

Monitoring: Regular liver function tests (LFTs) and blood counts are essential during treatment. Your doctor may adjust the dose based on your platelet count and side effects.

5. Frequently Asked Questions (FAQ)

Q1. What is Revolade 25mg used for?
A: It is primarily used to treat low platelet counts in chronic immune thrombocytopenia (ITP), chronic hepatitis C-related thrombocytopenia, and severe aplastic anemia.

Q2. How does Eltrombopag work?
A: Eltrombopag is a thrombopoietin receptor agonist. It binds to receptors in the bone marrow, stimulating it to produce more platelets.

Q3. When will I see an improvement in my platelet count?
A: Most patients begin to see an increase in platelet counts within 1 to 2 weeks of starting Revolade. Full response may take longer depending on individual conditions.

Q4. Can Revolade cure ITP or aplastic anemia?
A: Revolade helps manage these conditions but is not a cure. It is often used as a long-term therapy to maintain safe platelet levels and prevent complications.

Q5. Are there any food or drug interactions?
A: Yes. Avoid taking Revolade with dairy products or supplements containing calcium, aluminum, magnesium, or iron, as they can reduce its absorption. Take the tablet on an empty stomach or as directed by your doctor.