Sovihep V Tablet

1. Product Introduction

Sovihep V Tablet is a fixed-dose combination of two powerful antiviral medicines—Sofosbuvir (400mg) and Velpatasvir (100mg)—used to treat chronic Hepatitis C Virus (HCV) infection. Manufactured by Zydus Heptiza, this medicine represents a modern, highly effective treatment that offers hope for complete cure in most HCV-infected patients.

Sofosbuvir is a nucleotide polymerase inhibitor and Velpatasvir is a NS5A inhibitor. Together, they directly attack the virus, stopping its ability to multiply and spread in the liver. This combination is known as a direct-acting antiviral (DAA) therapy and is effective against all six major genotypes of the Hepatitis C virus, making it a pan-genotypic treatment option.

Sovihep V Tablet is typically taken once a day for a course of 12 weeks, and may be extended or combined with other medicines depending on the severity of the infection or presence of liver cirrhosis. This oral medication is revolutionizing HCV treatment by offering a cure with minimal side effects and a high success rate.

2. Uses of Sovihep V Tablet

Sovihep V Tablet is used for the treatment of:

• Chronic Hepatitis C Virus (HCV) infection in adult patients

• Treatment of all HCV genotypes (1-6)

• HCV in patients with or without cirrhosis

• Often used as monotherapy, but in cases of decompensated cirrhosis, may be used with Ribavirin

This medication is also prescribed to treatment-naïve patients and those who have failed previous HCV treatments, depending on their genotype and liver health.

3. Benefits of Sovihep V Tablet

✅ Pan-Genotypic Coverage: Effective against all types of Hepatitis C virus, reducing the need for genotype testing before treatment.

✅ High Cure Rate: Offers a cure rate of over 95% when taken as directed, with sustained virologic response (SVR).

✅ Simple Once-Daily Dosing: Oral administration with a single daily tablet improves convenience and adherence.

✅ Short Treatment Duration: Most treatment courses are completed in just 12 weeks, faster than traditional methods.

✅ Minimal Side Effects: Compared to interferon-based regimens, Sovihep V is significantly better tolerated.

✅ Prevents Disease Progression: Early treatment can prevent complications such as liver cirrhosis, liver failure, and hepatocellular carcinoma.

✅ Improves Liver Health: Reduces viral load and liver inflammation, helping restore liver function over time.

4. Side Effects

Sovihep V Tablet is generally well-tolerated, but like all medications, it may cause some side effects in certain individuals.

Common Side Effects:

• Fatigue

• Headache

• Nausea

• Diarrhea

• Insomnia

• Weakness

Less Common Side Effects:

• Dizziness

• Anemia (especially if taken with Ribavirin)

• Irritability or mood changes

• Muscle pain

• Loss of appetite

Important: If you experience symptoms such as yellowing of the eyes or skin, chest pain, shortness of breath, swelling, or a severe allergic reaction, seek immediate medical attention.

Patients with co-infections (HIV or Hepatitis B) or liver cirrhosis should be carefully monitored by healthcare providers.

5. Frequently Asked Questions (FAQs)

Q1. How does Sovihep V Tablet work?
A: It combines Sofosbuvir and Velpatasvir, which block essential viral proteins needed for the replication of the Hepatitis C virus, thus reducing viral levels and eventually eliminating the virus from the body.

Q2. Can Sovihep V cure Hepatitis C?
A: Yes. When taken for the prescribed duration (usually 12 weeks), Sovihep V can cure Hepatitis C in more than 95% of patients by achieving a sustained virologic response (SVR), meaning the virus becomes undetectable.

Q3. How long should I take Sovihep V?
A: Most patients take it for 12 weeks. In certain cases, such as decompensated liver disease or prior treatment failure, the doctor may recommend 24 weeks of therapy or adding another antiviral (Ribavirin).

Q4. Can I take Sovihep V with other medications?
A: Some medicines, especially those that affect liver enzymes (like anticonvulsants, rifampin, or St. John’s Wort), may reduce its effectiveness. Always inform your doctor about all medications, herbal supplements, or OTC drugs you’re taking.

Q5. What should I do if I miss a dose?
A: Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not take a double dose to make up for the missed one.