

Temolon 100mg Capsule
₹7,350.00 Original price was: ₹7,350.00.₹1,600.00Current price is: ₹1,600.00.
 Prescription Required
Salt : Temozolomide
Manufacturer : CELON LABORATORIES LTD
Packing : 5Â capsules in 1 strip
1. Product Introduction
Temolon 100mg Capsule is an oral chemotherapy medicine that contains Temozolomide, a powerful anti-cancer agent used to treat certain types of brain tumors. It is classified as an alkylating agent, which works by damaging the DNA of cancer cells and preventing their growth and division. This leads to the eventual destruction of the malignant cells.
Temolon 100mg is commonly used in the treatment of aggressive brain tumors like glioblastoma multiforme and anaplastic astrocytoma, especially when other treatments have not been effective or as part of a comprehensive cancer treatment plan including radiotherapy. It is administered under the guidance of a medical oncologist and may be used as both initial and maintenance therapy depending on the condition.
2. Uses of This Medicine
Temolon 100mg Capsule is primarily used to treat:
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Glioblastoma Multiforme (GBM): A highly aggressive and fast-growing type of brain cancer. Temozolomide is used in conjunction with radiotherapy during the initial phase and later as monotherapy in the maintenance phase.
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Anaplastic Astrocytoma: A rare and malignant brain tumor that may occur when other treatments have failed. Temozolomide helps control tumor growth and progression.
Other potential off-label uses may include certain types of metastatic melanoma or other tumors where alkylating agents have shown clinical benefits.
3. Benefits of This Medicine
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Targeted Cancer Treatment: Temozolomide specifically targets cancer cells by interrupting their DNA, reducing damage to normal cells.
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Oral Administration: Unlike many chemotherapies that require intravenous infusions, Temolon 100mg can be taken orally, offering convenience and allowing patients to maintain a more comfortable routine.
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Effective with Radiotherapy: When used alongside radiation therapy, it can significantly enhance treatment effectiveness, especially in newly diagnosed glioblastoma cases.
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Prolongs Survival: Clinical trials have shown that Temozolomide increases survival rates and reduces the rate of cancer recurrence.
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Well Tolerated: Compared to some traditional chemotherapy options, Temozolomide tends to have a more tolerable side effect profile for many patients.
4. Side Effects
Like all chemotherapy drugs, Temolon 100mg Capsule may cause side effects, though not everyone experiences them. It is important to monitor and report any adverse reactions to the doctor for appropriate management.
Common Side Effects:
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Nausea and vomiting
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Fatigue or weakness
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Headache
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Loss of appetite
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Constipation
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Hair thinning or hair loss
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Trouble sleeping
Serious Side Effects:
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Low Blood Cell Counts: Including anemia, leukopenia, and thrombocytopenia, which can lead to increased risk of infections, fatigue, or bleeding.
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Liver Problems: Elevated liver enzymes, jaundice.
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Seizures: Especially in patients with brain tumors.
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Infections: Due to a weakened immune system.
Rare Side Effects:
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Allergic reactions such as rash, itching, or swelling
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Respiratory infections or pneumonia
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Mood changes or confusion
Precautions:
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Regular blood tests are necessary to monitor liver function and blood cell counts.
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Not recommended during pregnancy or breastfeeding.
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Use effective contraception during treatment and for at least 6 months after the last dose.
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Inform the doctor about any other medications being taken to avoid interactions.
5. Frequently Asked Questions (FAQ)
Q1. What is Temolon 100mg used for?
A: It is used to treat certain types of brain cancers, particularly glioblastoma multiforme and anaplastic astrocytoma, often in combination with radiation therapy.
Q2. How should I take Temolon 100mg Capsule?
A: It should be taken once daily on an empty stomach, usually at the same time each day, as directed by your doctor. Swallow the capsule whole with water.
Q3. Can I take this medicine with food?
A: It is best taken on an empty stomach, at least one hour before or two hours after a meal, to improve absorption and effectiveness.
Q4. What should I do if I miss a dose?
A: If you miss a dose, take it as soon as you remember. If it’s close to your next scheduled dose, skip the missed dose. Do not double the dose.
Q5. Is Temolon 100mg safe during pregnancy?
A: No, it is not safe during pregnancy as it can harm the unborn baby. Effective contraception must be used by both men and women during and after treatment.
References
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Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1687.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1324-25.
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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Temozolamide. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
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