

Temotero 250mg Capsule
₹21,495.00 Original price was: ₹21,495.00.₹2,200.00Current price is: ₹2,200.00.
Prescription RequiredÂ
Salt : Temozolomide 250mg
Manufacturer : Cipla Ltd
Packing : 5 capsules in 1 strip
1. Product Introduction
Temotero 250mg Capsule is a prescription anti-cancer medication that contains Temozolomide 250mg as its active ingredient. It is a chemotherapy drug used in the treatment of certain aggressive types of brain tumors. Belonging to a class of drugs known as alkylating agents, Temozolomide works by damaging the DNA of cancer cells, thereby preventing them from multiplying and spreading.
Temotero is typically administered orally, offering convenience to patients compared to traditional intravenous chemotherapy treatments. It is widely used in combination with radiotherapy in the initial phase of treatment and also as a monotherapy during the maintenance phase.
This medicine is carefully prescribed by oncologists, and it is important to follow the prescribed dosage and schedule strictly to ensure the best outcomes and minimize side effects.
2. Uses of Temotero 250mg Capsule
Temotero 250mg is primarily indicated for the treatment of:
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Glioblastoma Multiforme (GBM):
A fast-growing and aggressive form of brain cancer. Temotero is often used in combination with radiation therapy for newly diagnosed patients and as monotherapy for recurrent cases. -
Anaplastic Astrocytoma:
A type of malignant brain tumor that arises from astrocytes. Temotero is used when the tumor recurs after initial treatments or when other treatments are not suitable. -
Other High-Grade Gliomas:
It may also be used off-label for other types of high-grade malignant gliomas, depending on the doctor’s assessment.
Temotero is usually administered in treatment cycles that include a period of medication followed by a rest period to allow the body to recover.
3. Benefits of Temotero 250mg Capsule
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Effective in Slowing Tumor Progression:
Temotero is highly effective in reducing the growth rate of aggressive brain tumors. It disrupts the DNA structure of rapidly dividing cancer cells, causing them to die or lose the ability to replicate. -
Oral Administration:
Unlike many other chemotherapy medications, Temotero is available in capsule form, which allows patients to take the medicine at home, thus reducing hospital visits. -
Improves Survival Rates:
Clinical studies have shown that combining Temotero with radiotherapy increases the overall survival rate in patients with glioblastoma multiforme. -
Better Quality of Life:
The convenience of oral dosing, fewer hospital stays, and manageable side effects contribute to a better quality of life during treatment. -
Used in Maintenance Therapy:
After initial intensive treatment, Temotero is used as a maintenance therapy to prevent recurrence and prolong survival.
4. Side Effects
Like all chemotherapy medications, Temotero 250mg Capsule may cause side effects. These vary from person to person and can be managed with appropriate care and support.
Common Side Effects:
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Nausea and vomiting
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Fatigue or general weakness
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Loss of appetite
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Headache
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Constipation
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Hair thinning or hair loss
Serious Side Effects (Require medical attention):
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Low blood cell counts (anemia, leukopenia, thrombocytopenia)
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Increased risk of infections
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Bleeding or bruising easily
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Severe allergic reactions like rash or swelling
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Liver function abnormalities
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Seizures or confusion (rare)
Precautions:
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Regular blood tests are necessary to monitor white and red blood cell counts as well as liver function.
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Avoid contact with people who are ill, due to decreased immunity.
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Contraceptive measures must be taken during treatment and for at least 6 months after the last dose.
5. Frequently Asked Questions (FAQ)
Q1. How should I take Temotero 250mg Capsule?
A: Take it exactly as prescribed by your doctor. Swallow the capsule whole with water, preferably on an empty stomach or at least 1 hour before or 2 hours after a meal. Do not open or crush the capsule.
Q2. Can Temotero cure brain cancer?
A: Temotero is not a cure, but it is effective in controlling tumor growth, delaying progression, and improving survival. Its success depends on the cancer type, stage, and overall patient health.
Q3. How long does Temotero treatment last?
A: The duration of treatment varies. For glioblastoma, it may be given during a 6-week radiotherapy phase, followed by 6 or more monthly cycles of maintenance therapy.
Q4. What should I do if I miss a dose?
A: If you miss a dose, contact your doctor immediately. Do not double up the next dose without medical advice. Timing and consistency are critical in chemotherapy.
Q5. Is it safe during pregnancy or breastfeeding?
A: No. Temotero can harm an unborn baby and should not be used during pregnancy or breastfeeding. Both male and female patients must use effective contraception during and after treatment.
References
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Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1687.
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1324-25.
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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Temozolamide. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
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