Thromplat 50mg Tablet

1. Product Introduction

Thromplat 50mg Tablet contains Eltrombopag, a thrombopoietin receptor agonist used to treat patients with low platelet counts due to specific blood disorders. It stimulates the production of platelets (blood-clotting cells) in the bone marrow, thus reducing the risk of bleeding complications in patients who are prone to thrombocytopenia (low platelet count).

Eltrombopag works by binding to and activating the thrombopoietin receptor, which leads to increased platelet production. It is especially beneficial for patients who cannot be treated effectively with standard therapies or require regular blood transfusions. Thromplat is typically prescribed when other options are insufficient or ineffective.

This medication is taken orally and is usually prescribed and monitored by a hematologist or oncologist based on the patient’s condition, platelet levels, and response to treatment.

2. Uses of Thromplat 50mg Tablet

Thromplat 50mg is prescribed for the following medical conditions:

• Chronic Immune Thrombocytopenia (ITP):
  For adults and children (over 1 year old) with ITP who have had an inadequate response to other treatments such as corticosteroids, immunoglobulins, or splenectomy.

• Chronic Hepatitis C-Associated Thrombocytopenia:
  To allow the initiation and maintenance of interferon-based therapy in patients with low platelet counts due to hepatitis C infection.

• Severe Aplastic Anemia (SAA):
  For patients with SAA who are unresponsive to immunosuppressive therapy or those who are ineligible for bone marrow transplantation.

3. Benefits of Thromplat 50mg Tablet

• Increases Platelet Count:
  Thromplat boosts the production of platelets in the bone marrow, helping to prevent bleeding episodes caused by low platelet levels.

• Reduces Dependence on Transfusions:
  For many patients, regular blood or platelet transfusions are required to manage their conditions. Thromplat can significantly reduce or eliminate the need for transfusions.

• Enables Antiviral Therapy in Hepatitis C:
  In patients with hepatitis C, low platelet counts may delay or prevent treatment. Eltrombopag allows for safe initiation and continuation of antiviral therapies.

• Improves Quality of Life:
  By reducing bleeding episodes, fatigue, and hospitalization, Thromplat improves patients’ daily life and overall health status.

• Effective in Refractory Cases:
  It is particularly beneficial for patients who do not respond to first-line treatments, offering an alternative that can achieve meaningful clinical outcomes.

• Oral Administration:
  Being an oral tablet, Thromplat is convenient to take at home without the need for injections or hospital visits.

4. Side Effects

While Thromplat is generally well-tolerated, it may cause some side effects. These effects can range from mild to severe, and not all patients will experience them.

Common Side Effects:

• Headache

• Nausea

• Diarrhea

• Fatigue

• Loss of appetite

• Upper respiratory tract infections

• Muscle aches or pain

Serious Side Effects:

• Liver problems: Elevated liver enzymes and liver toxicity may occur. Regular liver function monitoring is essential.

• Blood clots: There is a risk of thromboembolic events (e.g., deep vein thrombosis, pulmonary embolism) if platelet counts become too high.

• Cataracts: Long-term use may increase the risk of cataracts; regular eye examinations are advised.

• Bone marrow fibrosis: Prolonged use can lead to abnormal bone marrow changes.

Precautions:

• Regular monitoring of platelet count, liver enzymes, and eye exams is recommended.

• Do not take antacids or dairy products close to the time of taking this medicine, as it may reduce absorption.

• Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

5. Frequently Asked Questions (FAQ)

Q1. What is Thromplat 50mg Tablet used for?
A: It is used to treat low platelet counts in conditions like chronic immune thrombocytopenia (ITP), chronic hepatitis C-associated thrombocytopenia, and severe aplastic anemia.

Q2. How does Eltrombopag work?
A: Eltrombopag stimulates the thrombopoietin receptor on bone marrow cells, encouraging the production of new platelets and improving clotting ability.

Q3. When should I take Thromplat?
A: It should be taken on an empty stomach, either 1 hour before or 2 hours after meals, and not close to dairy or supplements containing calcium, magnesium, or iron.

Q4. How long does it take to show results?
A: Platelet counts usually start improving within 1 to 2 weeks. However, response time may vary depending on the individual and their condition.

Q5. Can Thromplat cure my condition?
A: Thromplat is not a cure but helps manage low platelet counts effectively. It can improve symptoms and reduce the need for other interventions.