Tiloshil 250mg Capsule

1. Product Introduction

Tiloshil 250mg Capsule is an oral chemotherapy medication that contains the active ingredient Temozolomide. It belongs to a class of drugs known as alkylating agents, which are used to treat certain types of brain tumors. Temozolomide works by interfering with the growth and spread of cancer cells in the body, making it an essential part of cancer treatment regimens.

Tiloshil is commonly used as a first-line or adjunctive therapy in the treatment of malignant gliomas, including glioblastoma multiforme and anaplastic astrocytoma. It is available in capsule form and is usually taken once daily, preferably on an empty stomach or as directed by a healthcare provider.

This medicine is prescribed under the supervision of an oncologist and is often used in conjunction with radiotherapy or other chemotherapeutic agents to enhance its effectiveness.

2. Uses of This Medicine

Tiloshil 250mg Capsule (Temozolomide) is primarily used in the treatment of the following cancers:

• Glioblastoma Multiforme (GBM):

  • A fast-growing and aggressive type of brain tumor.

  • Used during the initial treatment phase in combination with radiation therapy and as maintenance therapy afterward.

• Anaplastic Astrocytoma:

  • A type of malignant brain tumor that originates from astrocytes.

  • Used in patients with recurrent or progressive tumors.

• Recurrent High-Grade Gliomas:

  • Administered to patients who have not responded adequately to other therapies.

• Off-label Uses (as determined by the oncologist):

  • Occasionally used in the treatment of other cancers such as metastatic melanoma or neuroendocrine tumors in clinical research settings.

3. Benefits of This Medicine

Tiloshil 250mg Capsule offers several important therapeutic benefits in the management of aggressive brain cancers:

• Improves Survival Rates:

  • When used with radiotherapy, Temozolomide has been shown to improve overall survival in patients with glioblastoma.

• Oral Administration:

  • Offers the convenience of at-home treatment without the need for intravenous infusion, making cancer care more manageable.

• Crosses the Blood-Brain Barrier:

  • One of the few chemotherapy drugs that can reach brain tumors effectively due to its ability to cross into the central nervous system.

• Synergistic with Radiation:

  • Enhances the effectiveness of radiotherapy, offering better tumor control during the initial phase of treatment.

• Well-Tolerated:

  • Has a relatively manageable side-effect profile compared to many other chemotherapy drugs.

• Maintenance Therapy Option:

  • Allows for long-term cancer control by suppressing tumor regrowth in the maintenance phase after radiotherapy.

4. Side Effects

Like all chemotherapy medications, Tiloshil 250mg Capsule may cause side effects. However, not everyone experiences them, and many side effects can be managed effectively under medical supervision.

Common Side Effects:

• Nausea and vomiting

• Fatigue or weakness

• Constipation

• Loss of appetite

• Headache

• Hair thinning or hair loss

Serious Side Effects:

• Low blood cell counts (anemia, leukopenia, thrombocytopenia)

• Increased risk of infections

• Liver toxicity (elevated liver enzymes)

• Severe skin reactions

• Allergic reactions (rash, itching, swelling, difficulty breathing)

• Seizures (rare but serious)

It is important to undergo regular blood tests while on Tiloshil to monitor blood cell counts and liver function. Report any signs of infection, unusual bleeding, or persistent side effects to your doctor immediately.

5. Frequently Asked Questions (FAQ)

Q1: What is Tiloshil 250mg Capsule used for?
A: It is primarily used to treat aggressive brain tumors such as glioblastoma multiforme and anaplastic astrocytoma, either alone or in combination with radiation therapy.

Q2: How should I take Tiloshil capsules?
A: Take the capsule exactly as prescribed by your doctor, usually once a day on an empty stomach. Do not chew or break the capsule. Swallow it whole with a glass of water.

Q3: Can I take this medicine at home?
A: Yes, Tiloshil is designed for oral use and can be taken at home. However, you must be under regular medical supervision to monitor blood counts and liver function.

Q4: What happens if I miss a dose?
A: If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and resume your schedule. Do not double the dose to make up for a missed one.

Q5: Are there any dietary restrictions while taking Tiloshil?
A: There are no strict dietary restrictions, but it is advisable to take the medicine on an empty stomach for best absorption. Avoid alcohol and discuss any supplements with your doctor.