Uniprost 250mg Tablet

1. Product Introduction

Uniprost 250mg Tablet is an oral anti-cancer medication containing Abiraterone Acetate as its active ingredient. It is widely used in the treatment of prostate cancer, specifically in patients with metastatic castration-resistant prostate cancer (mCRPC) and metastatic high-risk castration-sensitive prostate cancer (mCSPC). This condition occurs when prostate cancer spreads beyond the prostate gland and continues to grow even after the reduction of testosterone levels, which usually fuel cancer cell growth.

Abiraterone Acetate belongs to a class of drugs known as androgen biosynthesis inhibitors. It works by selectively inhibiting CYP17 enzyme, which plays a crucial role in androgen (male hormone) production in the body. Since androgens promote the growth of prostate cancer cells, reducing their levels helps slow or stop tumor progression.

Uniprost 250mg is typically administered along with a corticosteroid such as prednisone to help manage hormone levels and reduce potential side effects. It is taken orally, on an empty stomach, and under strict medical supervision, usually as part of a long-term cancer therapy regimen.

2. Uses of This Medicine

Uniprost 250mg Tablet is used for:

• Treatment of metastatic castration-resistant prostate cancer (mCRPC) – when cancer continues to grow despite hormone therapy or surgical removal of the testicles.

• Treatment of metastatic castration-sensitive prostate cancer (mCSPC) – where the cancer is sensitive to hormone therapy but has already spread.

• Often prescribed in combination with prednisone or prednisolone to enhance treatment response and control side effects.

3. Benefits of This Medicine

Uniprost 250mg Tablet offers several clinically significant benefits to patients suffering from advanced prostate cancer:

• Slows Cancer Progression: By suppressing androgen production, Uniprost helps halt the growth and spread of prostate cancer cells, especially in advanced stages.

• Improves Overall Survival: Clinical studies have shown that patients receiving Abiraterone Acetate enjoy improved survival rates compared to those receiving standard hormone therapy alone.

• Delays Need for Chemotherapy: In many cases, Uniprost can postpone the need for chemotherapy, giving patients more time with fewer side effects.

• Symptom Relief: It helps reduce symptoms such as pain, difficulty urinating, and bone complications associated with prostate cancer spread.

• Convenient Oral Dosing: Being a tablet, it is easy to take at home and does not require hospital visits like intravenous chemotherapy.

• Enhanced Quality of Life: By controlling disease progression and easing symptoms, Uniprost contributes to improved physical and emotional well-being.

4. Side Effects

Like all medications, Uniprost 250mg Tablet may cause side effects in some individuals. Most are manageable and can be minimized with regular monitoring.

Common Side Effects:

• High blood pressure (hypertension)

• Swelling in hands, ankles, or feet (fluid retention)

• Low potassium levels (hypokalemia)

• Fatigue or general weakness

• Joint or muscle pain

• Hot flashes

• Elevated liver enzymes

Serious Side Effects (Less Common):

• Irregular heartbeat

• Adrenal insufficiency (body cannot produce enough steroid hormones)

• Liver toxicity or liver failure (rare)

• Allergic reactions (rash, itching, difficulty breathing)

Monitoring Requirements:

• Regular liver function tests

• Blood pressure monitoring

• Potassium level checks

• Assessment of heart health, especially for those with cardiac history

Important Note: This medicine should always be taken with a corticosteroid (usually prednisone) as directed by your doctor to help balance hormones and reduce the risk of serious side effects.

5. Frequently Asked Questions (FAQ)

Q1. What is Uniprost 250mg Tablet used for?
A: Uniprost is used to treat advanced prostate cancer, especially when the disease continues to progress after hormone-reducing treatments (mCRPC) or in metastatic hormone-sensitive prostate cancer (mCSPC).

Q2. How should I take Uniprost 250mg Tablet?
A: Take the tablet on an empty stomach, either 1 hour before or 2 hours after meals. Swallow it whole with water. It is usually taken once daily along with prednisone.

Q3. Can this medicine be used with other cancer therapies?
A: Yes. Uniprost is often used in combination with steroids and may also be part of a treatment plan that includes chemotherapy or hormone therapy.

Q4. How long should I continue taking this medication?
A: Treatment duration varies depending on your cancer’s response and progression. Your oncologist will determine how long you should continue therapy based on regular assessments.

Q5. Can I take Uniprost if I have liver or kidney problems?
A: Caution is advised. Dose adjustments may be needed for patients with liver impairment. Inform your doctor of any existing conditions before starting treatment.

Q6. Are there any dietary restrictions with Uniprost?