Versavo 100mg Injection

1. Product Introduction

Versavo 100mg Injection contains Bevacizumab, a recombinant monoclonal antibody that is used to treat various types of cancers. Bevacizumab works by targeting and inhibiting a protein known as vascular endothelial growth factor (VEGF). This protein plays a vital role in the formation of blood vessels (angiogenesis) that feed tumors. By blocking VEGF, Versavo helps cut off the blood supply that cancer cells need to grow and spread.

This medicine is given by slow intravenous infusion under strict medical supervision, usually in a hospital or chemotherapy center. It is often prescribed as part of a combination therapy with other chemotherapy agents.

Versavo is a biosimilar to Avastin (Bevacizumab) and offers a cost-effective and clinically equivalent alternative in cancer therapy.

2. Uses of Versavo 100mg Injection

Versavo is indicated for the treatment of several types of advanced or metastatic cancers. Common approved uses include:

• Colorectal Cancer (Metastatic): Often used in combination with 5-FU-based chemotherapy regimens.

• Non-Small Cell Lung Cancer (NSCLC): Especially for non-squamous, non-small cell types in combination with platinum-based chemotherapy.

• Glioblastoma (a type of brain tumor): Used in cases of recurrence.

• Metastatic Renal Cell Carcinoma (Kidney cancer): Often in combination with interferon.

• Cervical Cancer: As part of a combination chemotherapy regimen.

• Ovarian and Fallopian Tube Cancers: In both frontline and recurrence settings.

• Hepatocellular Carcinoma (Liver Cancer): In combination with atezolizumab in some protocols.

Versavo is not a standalone cure but significantly contributes to prolonging survival and slowing disease progression.

3. Benefits of Versavo 100mg Injection

• Inhibits tumor growth: By stopping the development of new blood vessels that feed cancer cells, Versavo helps control tumor size and spread.

• Enhances chemotherapy effectiveness: Improves delivery of other anti-cancer drugs to the tumor site when used in combination.

• Extended progression-free survival: Clinical studies have shown that patients receiving Bevacizumab tend to have longer disease control periods.

• Reduces tumor vascularization: Slows down metastasis by suppressing angiogenesis.

• Applicable across multiple cancers: Offers a treatment option for various solid tumors, especially in advanced stages.

• Biosimilar advantage: Versavo is more affordable while maintaining the same efficacy and safety profile as branded Bevacizumab (Avastin).

4. Side Effects

Like all powerful medications, Versavo 100mg Injection may cause side effects. It’s essential to be monitored regularly during treatment to ensure safety and effectiveness.

Common Side Effects:

• High blood pressure (hypertension)

• Nosebleeds or minor bleeding

• Headache

• Fatigue or weakness

• Protein in the urine

• Diarrhea or constipation

• Mouth sores

Serious Side Effects (Less Common):

• Blood clots (deep vein thrombosis or pulmonary embolism)

• Gastrointestinal perforations (rare but serious)

• Delayed wound healing

• Hemorrhages (bleeding in the lungs, brain, or GI tract)

• Kidney problems (nephrotic syndrome)

• Infections

• Heart problems (especially in patients with prior cardiac conditions)

Precautions:

• Not recommended during recent or upcoming surgeries.

• Caution in patients with heart, kidney, or bleeding disorders.

• Avoid in pregnancy or breastfeeding unless absolutely necessary.

Regular blood pressure monitoring, urine tests, and organ function tests are recommended during treatment with Versavo.

5. Frequently Asked Questions (FAQ)

Q1. What is Versavo 100mg Injection used for?
A: Versavo is used in the treatment of various advanced cancers including colorectal, lung, kidney, ovarian, brain, and cervical cancers. It is administered along with other chemotherapy drugs.

Q2. How does Bevacizumab work in cancer treatment?
A: Bevacizumab blocks a protein called VEGF that promotes blood vessel formation in tumors. This reduces the supply of nutrients to the tumor, slowing its growth.

Q3. How is Versavo administered?
A: It is given as an intravenous infusion over a set period. The dosage and frequency depend on the cancer type and the patient’s response to treatment.

Q4. Can Versavo be used alone?
A: While it has some standalone activity, Versavo is most effective when used in combination with other chemotherapy agents.

Q5. Are there any dietary restrictions during treatment?
A: There are no specific dietary restrictions, but a healthy, well-balanced diet is recommended. Always consult a doctor or dietician.