Viatran 1.5 gm Injection

1. Product Introduction

Viatran 1.5 gm Injection is a powerful combination antibiotic containing two active ingredients—Cefoperazone and Sulbactam. It belongs to the class of beta-lactam antibiotics and is widely used to treat a broad range of bacterial infections. Cefoperazone is a third-generation cephalosporin antibiotic that kills bacteria by interfering with their cell wall formation. Sulbactam, on the other hand, is a beta-lactamase inhibitor that enhances the activity of Cefoperazone by preventing bacterial resistance.

This dual-action formula ensures more effective treatment, especially for multi-drug resistant infections in critically ill patients. Viatran is generally administered in hospitals under the supervision of healthcare professionals. It is given via intravenous (IV) or intramuscular (IM) injection.

Viatran is known for its broad-spectrum antibacterial activity and is often used in serious infections where first-line antibiotics may not be effective. It plays a crucial role in treating infections of the respiratory tract, urinary tract, abdominal cavity, skin, and more.

2. Uses of Viatran 1.5 gm Injection

Viatran 1.5 gm Injection is prescribed for the treatment of various bacterial infections, including:

• Respiratory tract infections (e.g., pneumonia, bronchitis)

• Urinary tract infections (UTIs)

• Intra-abdominal infections (e.g., peritonitis)

• Skin and soft tissue infections

• Bone and joint infections

• Septicemia (blood infection)

• Gynecological infections (e.g., endometritis, pelvic inflammatory disease)

• Post-surgical infections

• Biliary tract infections

• Meningitis (in selected cases, with proper medical advice)

This antibiotic combination is especially valuable in hospital settings where bacterial resistance is a growing concern.

3. Benefits of Viatran 1.5 gm Injection

Viatran Injection offers a wide range of clinical advantages due to its dual-action composition:

• Broad-spectrum activity: Effective against both Gram-positive and Gram-negative bacteria.

• Enhanced effectiveness: Sulbactam boosts the action of Cefoperazone by inhibiting enzymes that cause resistance.

• Rapid symptom relief: Provides quick relief from infection-related symptoms like fever, swelling, and pain.

• Effective against resistant infections: Useful when standard antibiotics fail due to resistance.

• Safe in serious infections: Commonly used in hospitalized patients for severe or life-threatening infections.

• Reduced recurrence risk: Proper use ensures complete eradication of the infection, lowering the chance of recurrence.

• Trusted antibiotic: Widely used in both adult and pediatric populations in critical care settings.

4. Side Effects

While Viatran 1.5 gm Injection is generally well-tolerated, it may cause some side effects in certain individuals. These include:

Common Side Effects:

• Pain, redness, or swelling at the injection site

• Nausea or vomiting

• Diarrhea

• Rash or mild skin irritation

• Elevated liver enzymes (seen in blood tests)

Serious Side Effects (Seek immediate medical help):

• Allergic reactions (rash, itching, swelling, difficulty breathing)

• Severe diarrhea or abdominal cramps (may indicate Clostridium difficile infection)

• Jaundice (yellowing of eyes or skin)

• Irregular heartbeat or dizziness

• Seizures (very rare, usually in patients with kidney problems or on high doses)

Note: Inform your doctor about any existing allergies, especially to penicillins or cephalosporins, before using Viatran.

5. Frequently Asked Questions (FAQs)

Q1. What is Viatran 1.5 gm Injection used for?
Viatran is used to treat various bacterial infections, including respiratory, urinary, abdominal, and skin infections. It is effective against many drug-resistant bacteria.

Q2. How is Viatran administered?
Viatran is administered either through intravenous (IV) infusion or intramuscular (IM) injection, depending on the severity of the infection and the patient’s condition.

Q3. Can I take Viatran at home?
This injection should only be administered by a healthcare professional, usually in a hospital or clinical setting. Home administration is not recommended unless advised and supervised by a doctor.

Q4. Is Viatran safe during pregnancy or breastfeeding?
Viatran should be used during pregnancy or breastfeeding only if clearly prescribed by your doctor. Its safety profile is relatively acceptable but requires professional judgment.

Q5. How long does it take for Viatran to work?
Most patients start to notice improvement in symptoms within 2–3 days. However, the full course of treatment must be completed to avoid relapse or resistance.

REFERENCES

1. Conan MacDougall. Penicillins, Cephalosporins, and Other Beta-Lactam Antibiotics. Goodman & Gilman’s: The Pharmacological Basics of Therapeutics. 13th Edition. New York McGraw Hill Medical, 2018. Page – 1023-1038.

2. Lan, Shao-Huan, Shen-Peng Chang, Chih-Cheng Lai, Li-Chin Lu, and Hung-Jen Tang. Efficacy and safety of cefoperazone-sulbactam in empiric therapy for febrile neutropenia: A systemic review and meta-analysis. National Library of Medicine. February 2020. [Accessed on 23rd July 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034635/

3. Chiang, Tsung-Ta, Hung-Jen Tang, Cheng-Hsun Chiu, Te-Li Chen, Mao-Wang Ho, Chen-Hsiang Lee, Wang-Huei Sheng, and Ya-Sung Yang. Antimicrobial activities of cefoperazone-sulbactam in comparison to cefoperazone against clinical organisms from medical centers in Taiwan. Journal of Medical Sciences. December 2016. [Accessed on 23rd July 2024] https://www.jmedscindmc.com/article.asp?issn=1011-4564;year=2016;volume=36;issue=6;spage=229;epage=233;aulast=Chiang;aid=JMedSci_2016_36_6_229_196365

4. Pfizer Limited. Electronic Medicines Compendium (EMC). [Revised in April 2020] [Accessed on 23rd July 2024] https://labeling.pfizer.com/ShowLabeling.aspx?id=14800#:~:text=mEq)%20per%20gram.-,Sulbactam%20is%20an%20off%2Dwhite%20crystalline%20powder%20which%20is%20highly,(1.5%20mEq)%20per%20gram.

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