Vorifend 200mg Tablet

1. Product Introduction

Vorifend 200mg Tablet is an antifungal medicine that contains the active ingredient Voriconazole. It belongs to the class of drugs known as triazole antifungals. This medication is widely prescribed for the treatment of serious and potentially life-threatening fungal infections, particularly in patients with weakened immune systems.

Voriconazole works by inhibiting an enzyme that fungi need to build their cell membranes, effectively stopping the fungus from growing and spreading. Due to its broad-spectrum antifungal activity, it is highly effective against infections caused by Aspergillus, Candida, Fusarium, and Scedosporium species.

Vorifend 200mg Tablet is typically used when other antifungals are ineffective or not well-tolerated. It is taken orally, usually one hour before or after meals, and treatment duration depends on the type and severity of infection.

2. Uses of Vorifend 200mg Tablet

Vorifend 200mg Tablet is used to treat various serious fungal infections, particularly in immunocompromised patients (e.g., those undergoing chemotherapy, bone marrow transplant, or HIV/AIDS). The main indications include:

• Invasive Aspergillosis – A severe fungal infection affecting the lungs and other organs.

• Candidemia – Bloodstream infections caused by Candida species.

• Esophageal Candidiasis – A fungal infection of the esophagus.

• Fungal Infections in the Skin, Brain, and Eyes – Including rare or resistant fungal strains.

• Fusariosis and Scedosporiosis – Uncommon but life-threatening fungal infections.

• Empiric Therapy for Febrile Neutropenic Patients – Patients with low white blood cell counts and fever.

3. Benefits of Vorifend 200mg Tablet

• Broad-Spectrum Antifungal Action: Voriconazole is effective against a wide range of fungal pathogens, including strains that are resistant to other antifungal agents.

• High Oral Bioavailability: The tablet form ensures effective absorption, making it convenient for both in-hospital and outpatient care.

• Tissue Penetration: Voriconazole has excellent tissue distribution, including the lungs, kidneys, liver, brain, and eyes, making it ideal for deep or systemic fungal infections.

• Alternative for Resistant Cases: It is often prescribed when patients fail to respond to other antifungals like Amphotericin B or fluconazole.

• Life-Saving Therapy: In many cases, Vorifend helps to rapidly reduce the fungal load, minimize symptoms, and improve survival in critically ill patients.

4. Side Effects

While Vorifend 200mg Tablet is generally well-tolerated, like all medications, it may cause side effects. Most are mild and reversible, but some can be serious and require medical attention.

Common Side Effects:

• Headache

• Nausea or vomiting

• Diarrhea

• Skin rash

• Visual disturbances (blurry vision, color perception changes)

• Elevated liver enzymes

Serious Side Effects:

• Liver toxicity: Regular liver function tests are recommended during treatment.

• Severe skin reactions: Including Stevens-Johnson syndrome or photosensitivity.

• Hallucinations or confusion

• QT prolongation: A heart rhythm disturbance, especially when combined with other medications.

• Allergic reactions: Including swelling, itching, or breathing difficulty.

If any of these symptoms become severe or unusual, consult a healthcare provider immediately.

5. Frequently Asked Questions (FAQ)

Q1. What is Vorifend 200mg Tablet used for?
A: Vorifend is used to treat serious fungal infections like invasive aspergillosis, candidemia, and other systemic fungal infections, especially in patients with weakened immune systems.

Q2. How should I take this medicine?
A: Take Vorifend 200mg Tablet on an empty stomach, at least one hour before or after a meal. Follow your doctor’s dosage instructions carefully, and don’t stop treatment prematurely.

Q3. Can I take Vorifend if I have liver issues?
A: If you have liver disease, inform your doctor before starting the medication. Liver function should be monitored regularly during the course of treatment.

Q4. Is it safe to take this medicine during pregnancy?
A: No, Voriconazole is not recommended during pregnancy as it may harm the fetus. Women of childbearing age should use effective contraception during treatment.

Q5. Are there any food or drug interactions I should know about?
A: Avoid grapefruit juice and herbal supplements. Inform your doctor about all medications you’re taking, as Voriconazole interacts with drugs like rifampin, phenytoin, and certain anti-HIV medicines.