Votrient 200mg Tablet

1. Product Introduction

Votrient 200mg Tablet is a targeted anti-cancer medication that contains the active ingredient Pazopanib, which belongs to a class of medicines called tyrosine kinase inhibitors (TKIs). It is designed to interfere with the growth of cancer cells by blocking specific enzymes known as tyrosine kinases that play a key role in the formation of blood vessels (angiogenesis) that tumors need to grow and spread.

Votrient is an oral tablet and offers a convenient and effective treatment option for certain types of cancers. It is generally prescribed by oncologists for advanced kidney cancer and specific soft tissue sarcomas. The medication works by restricting the supply of blood and nutrients to cancer cells, slowing their growth and preventing further spread.

2. Uses of Votrient 200mg Tablet

Votrient 200mg is primarily used in the treatment of the following conditions:

• Advanced Renal Cell Carcinoma (RCC):
  It is used in patients with advanced stages of kidney cancer, especially when the disease has spread beyond the kidney.

• Advanced Soft Tissue Sarcoma (STS):
  Votrient is prescribed for certain types of soft tissue sarcomas in adults who have previously received chemotherapy for metastatic disease.

• Off-label Uses:
  Sometimes, oncologists may use Votrient in other cancers where angiogenesis inhibition is beneficial, although these are considered off-label.

3. Benefits of Votrient 200mg Tablet

• Targeted Cancer Therapy:
  Votrient offers a more focused approach compared to traditional chemotherapy. It targets cancer growth pathways while minimizing damage to healthy cells.

• Inhibits Tumor Blood Supply:
  By blocking VEGF receptors, Votrient limits the tumor’s access to blood vessels, effectively slowing down or stopping the growth and spread of cancer cells.

• Prolongs Progression-Free Survival:
  Clinical studies have shown that Votrient can extend the time before cancer progresses in both renal and soft tissue cancers.

• Convenient Oral Dosing:
  Taken as a tablet once daily, Votrient provides a non-invasive, home-based treatment option without the need for hospital-based infusions.

• Improves Quality of Life:
  In many cases, Votrient has helped patients maintain independence and daily function while undergoing cancer treatment.

4. Side Effects

Like all cancer medications, Votrient 200mg Tablet may cause side effects. It’s important for patients to be closely monitored by their doctor during treatment.

Common Side Effects:

• Nausea or vomiting

• Diarrhea

• Loss of appetite

• Fatigue or tiredness

• Hair color changes (graying)

• High blood pressure

• Weight loss

• Headache

Serious Side Effects (Require Immediate Medical Attention):

• Liver toxicity (symptoms: yellowing of eyes/skin, dark urine, pain in the upper right abdomen)

• Heart problems (irregular heartbeat, chest pain)

• Bleeding (nosebleeds, blood in urine or stool)

• Blood clot formation (swelling in limbs, shortness of breath)

• Gastrointestinal perforation (severe stomach pain, vomiting blood)

• Slow wound healing

Precautions:

• Patients with pre-existing liver, heart, or kidney disease should use this medication under strict medical supervision.

• Regular monitoring of liver enzymes, blood pressure, and heart function is essential.

• Avoid grapefruit juice while on Votrient as it can increase the risk of side effects.

• Women who are pregnant or breastfeeding should not take this medication.

5. Frequently Asked Questions (FAQ)

Q1. How does Votrient 200mg Tablet work?
Votrient works by blocking certain proteins (tyrosine kinases) that tumors need to grow and form blood vessels. This reduces the supply of oxygen and nutrients to cancer cells, thereby slowing their growth.

Q2. How should I take Votrient?
Take Votrient exactly as prescribed by your doctor. It is usually taken once daily on an empty stomach, at least one hour before or two hours after a meal. Swallow the tablet whole with water.

Q3. Can Votrient cure cancer?
Votrient is not a cure, but it can significantly delay the progression of certain cancers and improve symptoms. It helps manage the disease and improve survival outcomes.

Q4. What should I do if I miss a dose?
If you miss a dose and it’s less than 12 hours since your scheduled time, take it as soon as you remember. If more than 12 hours have passed, skip the missed dose—do not double up.

Q5. Is Votrient safe in elderly patients?
Yes, but elderly patients may be more sensitive to side effects like fatigue, high blood pressure, or liver issues. Regular monitoring is advised.