Xbira 250mg Tablet

1. Product Introduction

Xbira 250mg Tablet is a potent oral medication used in the treatment of prostate cancer. It contains Abiraterone Acetate (250mg) as its active ingredient, which is a hormonal therapy classified under androgen biosynthesis inhibitors. Xbira is manufactured to help reduce androgen (male hormone) production in the body, particularly testosterone, which is known to fuel the growth of prostate cancer cells.

Unlike traditional chemotherapy drugs, Xbira targets the hormonal pathway involved in cancer cell survival and progression. It is generally prescribed in combination with prednisone or prednisolone to manage potential side effects and improve the treatment’s effectiveness. Xbira is commonly used in advanced or metastatic stages of prostate cancer, especially in patients who have not responded well to other therapies.

This medicine is only available by prescription and should be taken under the supervision of a qualified oncologist or cancer specialist.

2. Uses of This Medicine

Xbira 250mg Tablet is primarily used for:

• Metastatic Castration-Resistant Prostate Cancer (mCRPC):
  This refers to prostate cancer that has spread beyond the prostate gland and continues to grow despite low levels of testosterone achieved by surgical or medical castration.

• Metastatic High-Risk Castration-Sensitive Prostate Cancer (mCSPC):
  Used in combination with androgen deprivation therapy (ADT) in patients with newly diagnosed metastatic prostate cancer who still respond to hormone therapy.

• Patients who previously underwent chemotherapy with docetaxel:
  Xbira is also beneficial for men whose cancer has progressed following chemotherapy.

It is a long-term therapy and part of a broader treatment plan involving other hormonal agents and supportive care.

3. Benefits of This Medicine

• Inhibits Cancer Progression:
  Xbira effectively reduces androgen production from the adrenal glands, testes, and tumor tissues, which significantly slows the growth of prostate cancer cells.

• Improves Survival Rates:
  Clinical trials have demonstrated that Abiraterone Acetate significantly prolongs overall survival and progression-free survival in men with advanced prostate cancer.

• Oral Convenience:
  Being an oral tablet, Xbira can be taken at home, reducing the need for hospital visits and intravenous treatments.

• Delays Need for Chemotherapy:
  For some patients, Xbira helps delay the requirement for more aggressive chemotherapy, thereby improving quality of life.

• Reduced Tumor Burden and Pain:
  Xbira can lead to a reduction in tumor size, alleviate cancer-related pain, and improve urinary symptoms associated with prostate cancer.

4. Side Effects

Like any potent medication, Xbira 250mg Tablet may cause side effects. While not everyone experiences them, it is important to be aware of the possible adverse reactions and report any unusual symptoms to your doctor.

Common Side Effects:

• Fatigue or weakness

• Joint pain or swelling

• Fluid retention (swelling in legs or ankles)

• High blood pressure

• Hot flashes

• Diarrhea

• Nausea or vomiting

Serious Side Effects:

• Hypokalemia (low potassium levels)

• Hepatotoxicity (liver function problems)

• Adrenal insufficiency

• Heart rhythm problems

• Shortness of breath or chest pain (rare)

Precautions:

• Liver function tests should be done regularly.

• Blood pressure and potassium levels must be monitored.

• Not suitable for women or children.

• Contraception should be used by men with partners of childbearing potential.

5. Frequently Asked Questions (FAQ)

Q1. How should I take Xbira 250mg Tablet?
A: Take the tablet on an empty stomach, preferably one hour before or two hours after eating. Swallow it whole with water. Do not crush, chew, or split the tablet. Follow your doctor’s instructions carefully.

Q2. Why is prednisone or prednisolone given along with Xbira?
A: Abiraterone can increase certain hormone levels in the body, leading to side effects like fluid retention, high blood pressure, and low potassium. Prednisone helps prevent or reduce these effects and improves treatment safety.

Q3. Can women take Xbira 250mg?
A: No, Xbira is not for use in women, especially not during pregnancy or breastfeeding. Exposure to the drug may cause harm to an unborn child.

Q4. What should I do if I miss a dose?
A: If you miss a dose, take it as soon as you remember. If it’s nearly time for your next dose, skip the missed one. Do not take two doses at once. Inform your doctor if multiple doses are missed.

Q5. How long will I need to take Xbira?
A: The duration varies depending on your response to treatment and disease progression. Your doctor will determine the treatment course based on periodic evaluations and test results.