Xbira 500mg Tablet

1. Product Introduction

Xbira 500mg Tablet is an oral anti-cancer medication that contains Abiraterone Acetate, a potent androgen biosynthesis inhibitor. It is primarily prescribed for the treatment of prostate cancer in adult men. Prostate cancer cells typically depend on androgens like testosterone to grow and spread. Xbira works by inhibiting an enzyme called CYP17, which is essential in the production of androgens in the body.

By blocking this enzyme, Xbira effectively lowers androgen levels, slowing the growth of prostate cancer cells. It is used in combination with prednisolone to reduce the risk of side effects related to hormone suppression and improve the overall treatment outcome.

This medicine is used in patients with metastatic castration-resistant prostate cancer (mCRPC) or metastatic high-risk castration-sensitive prostate cancer (mCSPC). It is not chemotherapy, but rather a targeted hormonal therapy that addresses the root hormonal cause of cancer progression.

2. Uses of This Medicine

Xbira 500mg Tablet is used for the treatment of:

• Metastatic Castration-Resistant Prostate Cancer (mCRPC):
  For men whose prostate cancer has spread to other parts of the body and is no longer responding to standard hormonal therapy.

• Metastatic High-Risk Castration-Sensitive Prostate Cancer (mCSPC):
  Used alongside androgen deprivation therapy (ADT) in men whose cancer has spread but still responds to hormone suppression.

• May also be used in combination with prednisolone to manage hormone-related side effects.

3. Benefits of This Medicine

• Inhibits Cancer Growth:
  Xbira effectively blocks androgen production, which helps slow the progression of prostate cancer.

• Extends Survival:
  Clinical studies have shown that Abiraterone improves overall survival and delays disease progression in advanced prostate cancer cases.

• Delays Chemotherapy:
  It can be used in earlier stages of advanced prostate cancer, helping patients delay or avoid the need for chemotherapy.

• Oral Administration:
  Offers a convenient, non-invasive treatment option that can be taken at home.

• Well Tolerated:
  When combined with low-dose prednisolone, the side effects are generally manageable, making it suitable for long-term use.

• Improves Quality of Life:
  By slowing disease progression and reducing symptoms, Xbira helps improve patient comfort and well-being.

4. Side Effects

While Xbira 500mg is generally well tolerated, like any medication, it may cause side effects in some patients. Most side effects are mild to moderate and manageable under medical supervision.

Common Side Effects:

• Fatigue or weakness

• Joint or muscle pain

• High blood pressure (hypertension)

• Fluid retention (swelling in legs or feet)

• Low potassium levels

• Increased liver enzymes

• Hot flashes

Less Common or Serious Side Effects:

• Liver toxicity (rare but serious)

• Heart-related issues like irregular heartbeat

• Adrenal gland problems

• Increased cholesterol or blood sugar levels

• Urinary tract infections

Monitoring Recommendations:

Regular monitoring of blood pressure, liver function, potassium levels, and blood sugar is advised during treatment with Xbira. Always follow your doctor’s advice regarding follow-up and lab tests.

5. Frequently Asked Questions (FAQ)

Q1. What is Xbira 500mg Tablet used for?
Xbira is used to treat advanced prostate cancer in men, especially in cases where the cancer has spread and is resistant or sensitive to traditional hormone therapy.

Q2. How does Xbira work?
Xbira contains Abiraterone Acetate, which inhibits the CYP17 enzyme responsible for androgen production. Lowering androgen levels helps slow or stop the growth of prostate cancer cells.

Q3. How should I take Xbira 500mg?
Take Xbira on an empty stomach, usually one hour before or two hours after a meal, once daily as prescribed by your doctor. It is typically taken with prednisolone.

Q4. Why is prednisolone given with Xbira?
Prednisolone helps prevent side effects caused by low cortisol levels that may result from androgen suppression by Xbira. It also enhances treatment effectiveness.

Q5. Can I stop taking Xbira if I feel better?
No. Do not stop or alter the dosage without your doctor’s guidance, even if you feel better. Stopping treatment early may lead to cancer progression.