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Absun 250mg Tablet
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Xostiv 250mg Tablet

Original price was: ₹27,500.00.Current price is: ₹8,000.00.

  Prescription Required 

Salt : Abiraterone Acetate

Manufacturer : ABBOTT

Packing : 120 tablets in 1 bottle

Description

1. Product Introduction

Xostiv 250mg Tablet is a prescription medication that contains Abiraterone Acetate, a powerful anti-cancer drug used primarily in the treatment of prostate cancer. It belongs to a class of medicines known as androgen biosynthesis inhibitors, which help reduce the levels of androgens (male hormones) in the body. High levels of androgens, especially testosterone, can promote the growth of prostate cancer cells. By suppressing these hormones, Xostiv slows the progression of the disease and improves overall survival in patients.

This medicine is usually prescribed in combination with prednisone or prednisolone to manage hormone-related side effects and improve treatment outcomes. Xostiv 250mg is typically given to patients with metastatic castration-resistant prostate cancer (mCRPC) or metastatic high-risk castration-sensitive prostate cancer (mCSPC).

Xostiv is taken orally and must be used strictly under medical supervision. Regular monitoring of liver function, blood pressure, and electrolyte levels is essential during the course of treatment.


2. Uses of Xostiv 250mg Tablet

  • Metastatic Castration-Resistant Prostate Cancer (mCRPC):
    Used in adult men whose prostate cancer has spread beyond the prostate gland and no longer responds to surgical or medical treatments that lower testosterone.

  • Metastatic High-Risk Castration-Sensitive Prostate Cancer (mCSPC):
    Prescribed to patients whose prostate cancer is newly diagnosed, has spread to other parts of the body, and is sensitive to hormone therapy.


3. Benefits of Xostiv 250mg Tablet

  • Slows Cancer Progression:
    Xostiv effectively lowers testosterone levels, which are responsible for the growth of prostate cancer cells. This slows down or even stops tumor growth.

  • Improves Survival Rate:
    When used in combination with corticosteroids, Xostiv has shown to increase overall survival and progression-free survival in patients with advanced prostate cancer.

  • Non-Invasive Oral Therapy:
    Xostiv is administered orally, making it a more convenient option for patients compared to injectable cancer therapies.

  • Improves Quality of Life:
    By reducing symptoms such as bone pain, urinary difficulties, and fatigue associated with prostate cancer, Xostiv helps improve the patient’s daily functioning and well-being.

  • Delays Disease Complications:
    It helps in delaying the need for chemotherapy, radiation, or other more invasive treatments.


4. Side Effects

Like all medications, Xostiv 250mg Tablet can cause some side effects. While not everyone experiences them, it’s essential to be aware of potential adverse reactions:

Common Side Effects:

  • High blood pressure (hypertension)

  • Low potassium levels (hypokalemia)

  • Fluid retention or swelling in legs and feet

  • Liver function abnormalities

  • Fatigue or weakness

  • Joint swelling or muscle pain

  • Hot flushes

  • Urinary tract infections

Serious Side Effects (Seek immediate medical help):

  • Severe liver damage (yellowing of skin/eyes, dark urine, persistent nausea)

  • Heart-related issues (irregular heartbeat, chest pain, shortness of breath)

  • Signs of adrenal insufficiency (dizziness, fainting, low blood pressure)

Note: Side effects can be managed with supportive medications and lifestyle changes. Regular monitoring by a healthcare provider is crucial to ensure safety during treatment.


5. Frequently Asked Questions (FAQs)

Q1. How should I take Xostiv 250mg Tablet?
A: Xostiv should be taken on an empty stomach, at least one hour before or two hours after meals. Swallow the tablet whole with a glass of water. It is usually taken once daily, along with prednisone as prescribed.

Q2. Why is Xostiv prescribed with prednisone?
A: Abiraterone can cause the body to produce more mineralocorticoids, which may lead to side effects like high blood pressure or low potassium. Prednisone helps counteract these effects and ensures treatment efficacy.

Q3. Can I stop taking Xostiv once I feel better?
A: No. You should not stop taking Xostiv unless advised by your doctor. Stopping it suddenly may lead to the return or worsening of prostate cancer symptoms.

Q4. Is Xostiv a chemotherapy drug?
A: No. Xostiv is a hormonal therapy drug, not chemotherapy. It works by reducing the production of testosterone, which fuels prostate cancer growth.

Q5. Can Xostiv be used in women or children?
A: No, Xostiv is not recommended for use in women or children. It is specifically developed for adult males with prostate cancer.


References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
  2. Abiraterone acetate. High Wycombe, Buckinghamshire: Janssen-Cilag Ltd.; 2017. [Accessed 26 Mar. 2019] (online) Available from:External Link
  3. Abiraterone Acetate. Patheon Inc.: Mississauga, Canada; 2011 [revised May 2016]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
  5. Abiraterone acetate [Prescribing Information]. Toronto, Canada: Patheon Inc.; 2011. [Accessed 20 Feb. 2024] (online) Available from: External Link
  6. CiplaMed. Abiraterone Acetate [Prescribing Information]. [Accessed 25 Jul. 2024] (online) Available from: External Link


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