

Zyceva 100mg Tablet
₹3,145.00 Original price was: ₹3,145.00.₹1,750.00Current price is: ₹1,750.00.
 Prescription Required
Salt : Erlotinib (100mg)
Manufacturer : Zydus Cadila
Packing : 30 Tablet(s) In A Bottle
1. Product Introduction
Zyceva 100mg Tablet is an oral prescription medicine that contains Erlotinib (100mg) as its active ingredient. It belongs to a class of medications known as tyrosine kinase inhibitors (TKIs) and is primarily used in the treatment of certain types of cancer, particularly non-small cell lung cancer (NSCLC) and pancreatic cancer. Erlotinib works by blocking the activity of a protein called epidermal growth factor receptor (EGFR), which plays a key role in the growth and spread of cancer cells.
Manufactured by Natco Pharma Ltd., Zyceva is a targeted therapy designed to slow down or stop the growth of cancer cells. It is available in tablet form and is usually taken orally, once daily on an empty stomach or as directed by the treating oncologist.
Zyceva is a significant advancement in the treatment of cancers with EGFR mutations, providing a more tailored and effective approach for eligible patients. Regular monitoring and follow-up are essential while using this medication to assess response and manage any side effects.
2. Uses of Zyceva 100mg Tablet
Zyceva 100mg Tablet is mainly prescribed for the following conditions:
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Non-Small Cell Lung Cancer (NSCLC):
Zyceva is used in patients with locally advanced or metastatic NSCLC who have specific EGFR mutations. It may be given as a first-line treatment or after failure of at least one prior chemotherapy regimen. -
Pancreatic Cancer:
In combination with gemcitabine, Zyceva is also used for treating patients with locally advanced, unresectable, or metastatic pancreatic cancer. -
Maintenance Therapy:
It may also be used as maintenance therapy in patients with NSCLC who have not progressed after 4 cycles of platinum-based chemotherapy.
3. Benefits of Zyceva 100mg Tablet
Zyceva 100mg Tablet offers several advantages for eligible cancer patients:
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Targeted Action:
Unlike conventional chemotherapy that affects all rapidly dividing cells, Zyceva specifically targets cancer cells with EGFR mutations, leading to fewer side effects and better efficacy. -
Improved Progression-Free Survival:
In patients with EGFR-mutated NSCLC, Zyceva has shown to significantly delay the progression of the disease compared to traditional chemotherapy. -
Oral Administration:
Being an oral tablet, Zyceva is more convenient than intravenous chemotherapy, allowing patients to take it from the comfort of their homes. -
Combination Use:
When used with other anticancer drugs like gemcitabine in pancreatic cancer, Zyceva can enhance the overall effectiveness of the treatment regimen. -
Personalized Medicine:
Zyceva represents a step forward in personalized cancer treatment, offering better results for patients whose tumors express EGFR mutations.
4. Side Effects of Zyceva 100mg Tablet
Like all cancer medications, Zyceva can cause side effects. Not everyone will experience them, and some may be mild or manageable. Common side effects include:
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Skin Reactions:
Rash, dryness, acne-like eruptions, and itching are common. These usually occur within the first few weeks of therapy. -
Diarrhea:
Often mild to moderate but can become severe in some cases. -
Fatigue:
Feeling unusually tired or weak is a common complaint among patients. -
Loss of Appetite and Weight Loss
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Nausea and Vomiting
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Mouth Sores and Dry Mouth
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Liver Function Changes:
Elevated liver enzymes may be seen in blood tests. -
Eye Irritation or Inflammation (Conjunctivitis)
Serious but rare side effects include:
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Interstitial lung disease
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Gastrointestinal perforation
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Severe liver damage
Patients should promptly report any signs of shortness of breath, severe abdominal pain, yellowing of eyes/skin, or persistent vomiting to their doctor.
5. Frequently Asked Questions (FAQs)
Q1. What is Zyceva 100mg Tablet used for?
Zyceva is primarily used to treat non-small cell lung cancer and pancreatic cancer in patients with EGFR mutations.
Q2. How should I take Zyceva 100mg Tablet?
Take it exactly as prescribed by your doctor, usually once daily on an empty stomach, at least 1 hour before or 2 hours after meals.
Q3. Can I take Zyceva with other medications?
Some medications and supplements can interact with Erlotinib. Inform your doctor about all other medicines you are taking before starting Zyceva.
Q4. Is Zyceva a form of chemotherapy?
Zyceva is not traditional chemotherapy. It is a targeted therapy that blocks EGFR, a protein involved in cancer cell growth.
Q5. How long do I need to take Zyceva?
The duration depends on your response to the treatment and your oncologist’s guidance. It may be taken for several months or longer if beneficial.
References
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines, 12th edition, 2011, 1735-1737.
- Mylan, Electronic medicines compendium (emc), [ Revised on Jan 2020] [ Accessed on 14th April 2021], https://www.medicines.org.uk/emc/files/pil.11264.pdf
- Genentech, US Food and Drug Administration, [ Revised on April 2010] [ Accessed on 14th April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021743s14s16lbl.pdf
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