Abiratas 500mg Tablet

1. Product Introduction

Abiratas 500mg Tablet is an advanced oral medication used in the treatment of prostate cancer. It contains Abiraterone Acetate, a powerful androgen biosynthesis inhibitor that plays a crucial role in hormone-related cancer therapy. This formulation is especially beneficial for patients diagnosed with metastatic castration-resistant prostate cancer (mCRPC) and metastatic castration-sensitive prostate cancer (mCSPC).

Abiraterone Acetate works by blocking the action of an enzyme called CYP17, which is essential for androgen (male hormone) production. Since prostate cancer cells rely on androgens to grow and survive, lowering these hormone levels slows the progression of the disease and helps reduce cancer-related symptoms.

The 500mg strength offers convenience by reducing the number of tablets needed per dose compared to 250mg variants, leading to better patient compliance and ease of use during long-term treatment. It is usually prescribed in combination with a corticosteroid such as prednisone, which helps reduce the side effects associated with hormone suppression.

2. Uses of This Medicine

Treatment of metastatic castration-resistant prostate cancer (mCRPC)

• Treatment of metastatic high-risk castration-sensitive prostate cancer (mCSPC)

• Prescribed in combination with corticosteroids like prednisone

• Helps in hormone suppression by blocking androgen production

• Effective in managing advanced stages of prostate cancer

3. Benefits of This Medicine

✔ Highly Effective Hormonal Control
Abiratas 500mg Tablet significantly reduces the levels of testosterone and other androgens, depriving prostate cancer cells of the hormones they need to grow. This slows the spread of cancer and alleviates related symptoms.

✔ Enhanced Dosage Convenience
With the higher strength of 500mg, patients often require fewer tablets daily compared to the 250mg dose, simplifying the medication schedule and improving adherence.

✔ Delays Progression of Prostate Cancer
By blocking androgen production, Abiratas helps delay disease progression in men with advanced prostate cancer, even when the cancer no longer responds to other hormonal treatments.

✔ Improves Quality of Life
Abiratas reduces symptoms such as bone pain, urinary problems, and fatigue. It also helps improve energy levels and daily functioning in patients battling late-stage cancer.

✔ Non-Invasive Oral Therapy
Abiratas is taken orally, making it a less invasive alternative to injectable therapies. This enhances comfort and convenience, especially for elderly patients or those on long-term cancer management plans.

✔ Proven Clinical Benefits
Clinical trials and real-world data show that Abiraterone-based treatments can extend survival and reduce cancer-related complications when used early in metastatic prostate cancer.

4. Side Effects

Like any medication, Abiratas 500mg Tablet may cause side effects. Not all patients experience them, and most side effects are manageable with proper monitoring.

Common Side Effects:

• High blood pressure (hypertension)

• Low blood potassium levels (hypokalemia)

• Swelling in hands, feet, or ankles (fluid retention)

• Increased liver enzymes

• Muscle and joint pain

• Fatigue

• Indigestion or upset stomach

• Hot flushes

Serious Side Effects (Seek medical help immediately):

• Liver damage (signs: yellowing of eyes/skin, dark urine, abdominal pain)

• Irregular heartbeat

• Severe dizziness or fainting

• Shortness of breath

• Signs of adrenal insufficiency (weakness, nausea, confusion)

• Allergic reactions (rash, itching, swelling of face or throat)

Important Note:
Routine blood pressure monitoring, liver function tests, and electrolyte checks (especially potassium) are strongly advised during the course of this treatment. Always follow your doctor’s advice and report unusual symptoms.

5. Frequently Asked Questions (FAQ)

Q1. What is Abiratas 500mg Tablet used for?
A: It is used in the treatment of advanced prostate cancer, particularly when the disease has spread beyond the prostate and is either resistant or sensitive to hormonal therapy.

Q2. How does Abiratas 500mg work?
A: It inhibits an enzyme called CYP17, which is involved in the production of testosterone. By reducing testosterone levels, it slows or stops the growth of prostate cancer cells.

Q3. Can I take Abiratas with food?
A: No. It should be taken on an empty stomach, at least one hour before or two hours after eating, as food can increase the absorption of the drug and lead to side effects.

Q4. Why is Abiratas given with prednisone?
A: Abiratas reduces the body’s natural corticosteroid levels. Prednisone is prescribed alongside to help prevent hormonal imbalances and side effects like adrenal insufficiency and high blood pressure.

Q5. How long should I take Abiratas 500mg?
A: The treatment duration varies depending on your response to therapy. Some patients may take it for several months or longer under medical supervision.