

Arbitus 500mg Tablet
₹39,500.00 Original price was: ₹39,500.00.₹10,000.00Current price is: ₹10,000.00.
Prescription Required
Salt : Abiraterone Acetate
Manufacturer : Dr Reddy’s Laboratories Ltd
Packing : 120 Tablet(s) In A Bottle
1. Product Introduction
Arbitus 500mg Tablet is a prescription medication containing Abiraterone Acetate as its active ingredient. It belongs to a class of drugs known as androgen biosynthesis inhibitors, primarily used in the treatment of prostate cancer. Prostate cancer is one of the most common cancers in men, and its progression is often driven by male hormones called androgens, particularly testosterone. Arbitus works by reducing the production of these hormones, thereby helping to slow or stop the growth of cancer cells.
Manufactured under strict quality standards, Arbitus 500mg is commonly prescribed along with prednisone to help manage the body’s hormonal response and minimize potential side effects related to adrenal suppression. It is used in men whose prostate cancer has spread to other parts of the body (metastatic) and is no longer responding to surgical or medical treatments to lower testosterone levels.
This medicine is not suitable for use in women or children. It should only be taken under the guidance and supervision of a qualified healthcare provider, who will monitor your progress regularly through blood tests and clinical evaluation.
2. Uses of this Medicine
Arbitus 500mg Tablet is used for:
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Treatment of metastatic castration-resistant prostate cancer (mCRPC) – prostate cancer that continues to progress despite low testosterone levels.
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Treatment of metastatic high-risk castration-sensitive prostate cancer (mCSPC) in combination with other therapies.
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Often combined with prednisone or prednisolone to reduce the risk of side effects caused by steroid hormone suppression.
3. Benefits of this Medicine
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Slows cancer progression: By inhibiting androgen production, Arbitus effectively slows down or halts the growth and spread of prostate cancer cells.
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Improves survival rates: Clinical studies have shown that patients taking Abiraterone experience longer overall survival when used appropriately.
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Better quality of life: Reducing symptoms such as bone pain, fatigue, and urinary discomfort often helps patients live more comfortably.
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Non-invasive alternative: As an oral medication, it offers a convenient, non-surgical treatment option for advanced prostate cancer.
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Reduced testosterone production: It blocks an enzyme (CYP17) essential for testosterone production in the adrenal glands, testes, and prostate tumor tissue.
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Supports other therapies: Often used alongside hormonal therapies, Arbitus enhances treatment efficacy when used in combination regimens.
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Convenient dosing: Usually taken once daily on an empty stomach, simplifying patient adherence to therapy.
4. Side Effects
While Arbitus 500mg Tablet is generally well-tolerated, some patients may experience side effects. These can vary in intensity and duration. It’s important to report any persistent or severe symptoms to your healthcare provider.
Common side effects include:
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Fatigue or tiredness
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Joint swelling or discomfort
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Increased blood pressure (hypertension)
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Fluid retention (swelling in the legs or ankles)
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Low potassium levels (hypokalemia)
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Hot flashes
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Increased liver enzymes (may require dose adjustments)
Less common but serious side effects:
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Adrenal insufficiency (due to reduced steroid hormone levels)
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Liver toxicity
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Cardiac problems such as irregular heartbeat or chest pain
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Severe allergic reactions (rare)
Regular blood tests are usually required to monitor liver function, potassium levels, and other parameters during treatment. Taking the medicine exactly as prescribed and following up with your doctor can help manage side effects effectively.
5. Frequently Asked Questions (FAQ)
Q1. How should I take Arbitus 500mg Tablet?
A: Arbitus should be taken orally once daily on an empty stomach (at least 1 hour before or 2 hours after eating). It’s often taken with prednisone to help manage side effects. Always follow your doctor’s instructions.
Q2. Can women take Arbitus 500mg Tablet?
A: No. Arbitus is specifically indicated for use in men with prostate cancer. It is not recommended for use in women and should not be used during pregnancy or breastfeeding due to potential harm.
Q3. What if I miss a dose?
A: If you miss a dose, take it as soon as you remember, unless it’s close to the time for your next dose. Do not take a double dose to make up for the missed one. Consult your doctor for specific instructions.
Q4. Can Arbitus cure prostate cancer?
A: Arbitus is not a cure for prostate cancer but helps manage and slow the disease’s progression. It improves survival and quality of life, especially in advanced stages.
Q5. Are there any dietary restrictions while using this medicine?
A: Yes. It should be taken on an empty stomach. Avoid food intake at least 2 hours before and 1 hour after taking the medicine, as food increases the drug’s absorption and may increase side effects.
References
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Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
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CiplaMed. Abiraterone Acetate [Prescribing Information]. [Accessed 25 Jul. 2024] (online) Available from:
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